The JAK2 V617F somatic mutation, mortality and cancer risk in ... | JAK2 V617F mutation

NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutJournalListHaematologicav.96(3);2011MarPMC3046277Haematologica.2011Mar;96(3):450–453.Publishedonline2010Dec15.doi: 10.3324/haematol.2010.033191PMCID:PMC3046277PMID:21160067TheJAK2V617Fsomaticmutation,mortalityandcancerriskinthegeneralpopulationCamillaNielsen,1HenrikS.Birgens,2BørgeG.Nordestgaard,1,3LasseKjær,2andStigE.Bojesen1,3CamillaNielsen1DepartmentofClinicalBiochemistryandFindarticlesbyCamillaNielsenHenrikS.Birgens2DepartmentofHematology,HerlevHospital,CopenhagenUniversityHospitalFindarticlesbyHenrikS.BirgensBørgeG.Nordestgaard1DepartmentofClinicalBiochemistryand3TheCopenhagenCityHeartStudy,BispebjergHospital,CopenhagenUniversityHospitalandFindarticlesbyBørgeG.NordestgaardLasseKjær2DepartmentofHematology,HerlevHospital,CopenhagenUniversityHospitalFindarticlesbyLasseKjærStigE.Bojesen1DepartmentofClinicalBiochemistryand3TheCopenhagenCityHeartStudy,BispebjergHospital,CopenhagenUniversityHospitalandFindarticlesbyStigE.BojesenAuthorinformationArticlenotesCopyrightandLicenseinformationDisclaimer1–3FacultyofHealthSciences,UniversityofCopenhagen,Denmark1DepartmentofClinicalBiochemistryand2DepartmentofHematology,HerlevHospital,CopenhagenUniversityHospital3TheCopenhagenCityHeartStudy,BispebjergHospital,CopenhagenUniversityHospitalandCorrespondence:StigE.Bojesen,DepartmentofClinicalBiochemistry,54M1,HerlevHospital,CopenhagenUniversityHospital,HerlevRingvej75,2730Herlev,Denmark.Phone:international+45.44883843.Fax:international+45.44883311.E-mail:kd.hnoiger.heh@obetsCNandHSBcontributedequallytothismanuscript.Received2010Sep17;Revised2010Nov24;Accepted2010Dec13.Copyright©FerrataStortiFoundationThisarticlehasbeencitedbyotherarticlesinPMC.JAK2V617Fispresentinthemajorityofpatientswithmyeloproliferativecancer;however,itsprevalenceandclinicalsignificanceinthegeneralpopulationisunknown.Wescreenedforpresenceofthemutationin10,507participantsfromtheCopenhagenCityHeartStudywithupto17.6yearso

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