全書63章,由80多位著名專家共同完成，是最前沿、全面的以胃腸病學和肝臟病學為主題的專業書，全書包括常見疾病的臨床表現、患者的評估、消化系統紊亂、消化系統感染、肝膽疾病、肝移植、胰腺疾病、消化系統腫瘤、營養、肥胖和飲食失調等內容，涵蓋了遺傳學、細胞生物學、病理生理學及治療的最新進展。

本書以簡潔、全彩為特色，提供本領域全新的具有科學嚴謹性和權威性的知識，非常適合教師、診所和病房醫生使用，也是醫學生認證考試的必備書。
 

Dennis L.Kasper博士是威廉埃勒裡強尼的醫學教授；任哈佛醫學院微生物學與免疫生物學系免疫分部微生物學和免疫生物學教授；同時在麻塞諸塞州的波士頓布萊根婦女醫院任職。
 

Contributors. . ix
Preface. . xiii
SECTION I
CARDINAL MANIFESTATIONS OF GASTROINTESTINAL DISEASE
1 Abdominal Pain. . 2
Danny O. Jacobs, William Silen
2 Oral Manifestations of Disease. . .. . 9
Samuel C. Durso
3 Atlas of Oral Manifestations of Disease. . .. 21
Samuel C. Durso, Janet A. Yellowitz
4 Dysphagia. . .. 27
Ikuo Hirano, Peter J. Kahrilas
5 Nausea, Vomiting, and Indigestion. . 32
William L. Hasler
6 Diarrhea and Constipation. . 41
Michael Camilleri, Joseph A. Murray
7 Gastrointestinal Bleeding. . .. 57
Loren Laine
8 Jaundice. . 62
Savio John, Daniel S. Pratt
9 Abdominal Swelling and Ascites. . 70
Kathleen E. Corey, Lawrence S. Friedman
10 Involuntary Weight Loss. . 75
Russell G. Robertson, J. Larry Jameson
SECTION II
EVALUATION OF THE PATIENT WITH ALIMENTARY TRACT SYNDROMES
11 Approach to the Patient with Gastrointestinal Disease. . 80
William L. Hasler, Chung Owyang
12 Gastrointestinal Endoscopy. . .. 89
Louis Michel Wong Kee Song, Mark Topazian
13 Video Atlas of Gastrointestinal Endoscopy. . 116
Louis Michel Wong Kee Song, Mark Topazian
SECTION III
DISORDERS OF THE ALIMENTARY TRACT
14 Diseases of the Esophagus. . .. . 118
Peter J. Kahrilas, Ikuo Hirano
15 Peptic Ulcer Disease and Related Disorders. . .. 134
John Del Valle
16 Disorders of Absorption. . 165
Henry J. Binder
17 The Schilling Test. . 186
Henry J. Binder
18 Inflammatory Bowel Disease. . .. 188
Sonia Friedman, Richard S. Blumberg
19 Irritable Bowel Syndrome. . 215
Chung Owyang
20 Diverticular Disease and Common
Anorectal Disorders. . 224
Rizwan Ahmed, Susan L. Gearhart
21 Mesenteric Vascular Insufficiency. . 236
Rizwan Ahmed, Mahmoud Malas
22 Acute Intestinal Obstruction. . .. 240
Danny O. Jacobs
23 Acute Appendicitis and Peritonitis. . 247
Danny O. Jacobs
SECTION IV
INFECTIONS OF THE ALIMENTARY TRACT
24 Acute Infectious Diarrheal Diseases
and Bacterial Food Poisoning. . 254
Regina C. LaRocque, Edward T. Ryan,
Stephen B. Calderwood
25 Clostridium difficile Infection, Including Pseudomembranous Colitis. 263
Dale N. Gerding, Stuart Johnson
26 Intraabdominal Infections and Abscesses. . 269
Miriam Baron Barshak, Dennis L. Kasper
27 Helicobacter pylori Infections. 279
John C. Atherton, Martin J. Blaser
CONTENTS
Gastroenterology_
28 Salmonellosis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286
David A. Pegues, Samuel I. Miller
29 Shigellosis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .296
Philippe J. Sansonetti, Jean Bergounioux
30 Infections Due to Campylobacter and
Related Organisms. 302
Martin J. Blaser
31 Cholera and Other Vibrioses. . . . . . . . . . . . . . . . . 307
Matthew K. Waldor, Edward T. Ryan
32 Viral Gastroenteritis. . . . . . . . . . . . . . . . . . . . . . . . . 315
Umesh D. Parashar, Roger I. Glass
33 Amebiasis and Infection with Free-Living
Amebas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322
Rosa M. Andrade, Sharon L. Reed
34 Protozoal Intestinal Infections and
Trichomoniasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . .330
Peter F. Weller
35 Intestinal Nematode Infections. . . . . . . . . . . . . . . 338
Peter F. Weller, Thomas B. Nutman
SECTION V
EVALUATION OF THE PATIENT
WITH LIVER DISEASE
36 Approach to the Patient with Liver Disease. . . . .346
Marc G. Ghany, Jay H. Hoofnagle
37 Evaluation of Liver Function. . . . . . . . . . . . . . . . . . 356
Daniel S. Pratt
SECTION VI
DISORDERS OF THE LIVER AND
BILIARY TREE
38 The Hyperbilirubinemias. . . . . . . . . . . . . . . . . . . . . 364
Allan W. Wolkoff
39 Acute Viral Hepatitis. . . . . . . . . . . . . . . . . . . . . . . .373
Jules L. Dienstag
40 Toxic and Drug-Induced Hepatitis . . . . . . . . . . . .402
William M. Lee, Jules L. Dienstag
41 Chronic Hepatitis. . . . . . . . . . . . . . . . . . . . . . . . . . .414
Jules L. Dienstag
42 Alcoholic Liver Disease. . . . . . . . . . . . . . . . . . . . . .446
Mark E. Mailliard, Michael F. Sorrell
43 Nonalcoholic Fatty Liver Diseases and
Nonalcoholic Steatohepatitis. . . . . . . . . . . . . . . . . . 450
Manal F. Abdelmalek, Anna Mae Diehl
44 Cirrhosis and Its Complications. . . . . . . . . . . . . . . 456
Bruce R. Bacon
45 Atlas of Liver Biopsies . . . . . . . . . . . . . . . . . . . . . . .471
Jules L. Dienstag, Atul K. Bhan
46 Genetic, Metabolic, and Infiltrative
Diseases Affecting the Liver. . . . . . . . . . . . . . . . . . . 477
Bruce R. Bacon
47 Diseases of the Gallbladder and Bile Ducts. . . . . . 482
Norton J. Greenberger, Gustav Paumgartner
SECTION VII
LIVER TRANSPLANTATION
48 Liver Transplantation. . . . . . . . . . . . . . . . . . . . . . . . 500
Raymond T. Chung, Jules L. Dienstag
SECTION VIII
DISORDERS OF THE PANCREAS
49 Approach to the Patient with Pancreatic
Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .514
Darwin L. Conwell, Norton J. Greenberger,
Peter A. Banks
50 Acute and Chronic Pancreatitis. . . . . . . . . . . . . . .520
Darwin L. Conwell, Peter A. Banks,
Norton J. Greenberger
SECTION IX
NEOPLASTIC DISEASES OF THE
GASTROINTESTINAL
SYSTEM
51 Upper Gastrointestinal Tract Cancers. . . . . . . . . . 540
Robert J. Mayer
52 Lower Gastrointestinal Cancers. . . . . . . . . . . . . . .549
Robert J. Mayer
53 Tumors of the Liver and Biliary Tree. . . . . . . . . . . 559
Brian I. Carr
54 Pancreatic Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . .574
Elizabeth Smyth, David Cunningham
55 Endocrine Tumors of the Gastrointestinal
Tract and Pancreas. . . . . . . . . . . . . . . . . . . . . . . . . .580
Robert T. Jensen
Gastroenterology
SECTION X
NUTRITION
56 Nutrient Requirements and Dietary
Assessment. . .. 608
Johanna Dwyer
57 Vitamin and Trace Mineral Deficiency
and Excess. . 619
Robert M. Russell, Paolo M. Suter
58 Malnutrition and Nutritional
Assessment. . .. 635
Douglas C. Heimburger
59 Enteral and Parenteral Nutrition
Therapy. . .. 644
Bruce R. Bistrian, L. John Hoffer,
David F. Driscoll
SECTION XI
OBESITY AND EATING DISORDERS
60 Biology of Obesity. . .. 660
Jeffrey S. Flier, Eleftheria Maratos-Flier
61 Evaluation and Management of Obesity. . 670
Robert F. Kushner
62 Eating Disorders. . 680
Victor I. Reus
63 The Metabolic Syndrome. . .. 682
Robert H. Eckel
Review and Self-Assessment. . 691
Charles M. Wiener, Cynthia D. Brown,
Brian Houston
Index. . 741