Capillaria philippinensis (C. philippinensis) is a rare food-borne nematodiasis that has appeared in more than 12 regions or countries worldwide ...SkiptomaincontentAdvertisementSearchallBMCarticlesSearchDownloadPDFCaseReportOpenAccessPublished:05October2012SeriousdiarrheawithweightlosscausedbyCapillariaphilippinensisacquiredinChina:acasereportZhigangFan1,YongdongHuang2,ShiyunQian1,GangLv1,YiyaoChen2,BoYang2,SaifengZhong1,GuifenLin1&GuogangYan3 BMCResearchNotesvolume 5,Article number: 554(2012)Citethisarticle5843Accesses6CitationsMetricsdetailsAbstractBackgroundDiarrheacausedbyCapillariaphilippinensis(C.philippinensis)hasnotbeenreportedinanyareaswiththeexceptionofTaiwanprovinceinChina.WehereinreportthemisdiagnosisandsubsequentmanagementofapatientwithdiarrheacausedbyC.philippinensis.CasepresentationA33-year-oldwomanfromtheoutskirtsofDanzhoucity,Hainanprovince,China,hadan11-monthhistoryofchronicdiarrheawithabdominalpain,edema,hypoalbuminemia,andsevereweightloss.Thepatientwasmisdiagnosedatanoutpatientclinicandonehospital.ShewasfinallycorrectlydiagnosedwithC.philippinensisbystoolexamination.Thepatientwasgivena30-dayscourseofalbendazole(400mg/day)andhadanuneventfulandstablerecovery.ConclusionDoctorscannotlosesightofpatients’dietaryhistories,mustquerystoolexaminationresults,andneedtoexpandtheirknowledgeofcertainnonlocalandglobaldiseases,especiallythosedescribedinnewcasereports.Somediagnosticexaminationsmustbeperformedrepeatedly.HainanprovincemaybetheepidemicfocusofC.philippinensis.BackgroundParasitesarerarelysuspectedascausesfordiarrhealepisodesbecauseoftheirdecreasinginfestationratesandendemiczones.Capillariaphilippinensis(C.philippinensis)isararefood-bornenematodiasisthathasappearedinmorethan12regionsorcountriesworldwide,includingthePhilippines[1],Indonesia[2],Thailand[3],LaoPeople’sDemocraticRepublic[4],India[5],Iran[6],Korea[7],andJapan[8].Morethan2000casesinvolvingalmost200deathshavebeendocumentedworldwide.However,nocaseshavebeenreportedinChinawiththeexceptionofTaiwa

 history&epidemiology C.philippinensisisalsoknownas‘Pudocworm’inthePhilippines,whereitisendemic.Thisaliasisbasedonthenameofthelocationwherethediseaseandtheassociatedwormwerefirstdiscoveredin1963. Figure3:endemicregion discoveryofdiseaseIn1962,ahealthyyoungmanfromLuzon,Philippinesrapidlyfellill,sufferingfromthekeyclinicalsymptomsthatwenowrecognizeasindicativeofparasiticCapillariainfection. PostmortemexaminationrevealedalargenumberofC.Philippinensiswormsinthelargeandsmallintestines. Hewasthefirstdocumentedcasualtyofhumanintestinalcapillariasis.historyofepidemicsDuringtheyears1967-1968,anepidemicinthePhilippinesinvolvedatleast1300infectedindividuals,90ofwhomdied.Anotherbriefepidemic,beginninginlate1978andendinginearly1979,involvedabout50infectedindividuals,alsotookplace.SporadiccaseshavecontinuedtoappearinnorthernLuzonaswellasinotherareaswhereepidemicshaveoccurred. geographyofinfectionsCapillariaspp.aremostcommonlyfoundinthePhilippinesbutcaseshavealsobeendocumentedinThailand,Iran,Japan,Egypt,SouthofTaiwan(Kaoh-Siung),Korea,Italy,Spain,andColombia.epidemiologyHumanintestinalcapillariasisisrare. TheCDCreportsonly1500documentedcasesofintestinalcapillariasissince1963,witha10%case-fatalityrate.Hepaticandpulmonarycapillariasisinhumansareextremelyrare,withamaximumof50casesdocumentedworldwide.Humanscontracttheseinfectionsbyingestingsoilthathasbeeninfectedbytheinfectedfecesofanimalsharboringtheparasite.Thediseaseismostcommoninchildrenhavingahistoryofpica.introduction   biologicalagent   lifecycle&transmission  clinicalpresentation   diagnosis   treatment&prevention 

SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkDPDx-LaboratoryIdentificationofParasitesofPublicHealthConcernSectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateIntestinalCapillariasisMinusRelatedPages[Capillariaphilippinensis]ParasiteBiologyImageGalleryLaboratoryDiagnosticResourcesCausalAgentThenematode(roundworm)Capillaria(=Paracapillaria)philippinensiscauseshumanintestinalcapillariasis.UnlikeC.hepatica,humansaremostlikelythemaindefinitivehost.Transmissionoccursprimarilythrougheatingundercookedfish.LifeCycleViewLargerTypically,unembryonated,thick-shelledeggsarepassedinthehumanstoolandbecomeembryonatedintheexternalenvironmentin5—10days;afteringestionbyfreshwaterfish,larvaehatch,penetratetheintestine,andmigratetothetissues.Ingestionofraworundercookedfishresultsininfectionofthehumanhost.TheadultsofCapillariaphilippinensisareverysmall(males:2.3to3.2mm;females:2.5to4.3mm)andresideinthehumansmallintestine,wheretheyburrowinthemucosa.Inadditiontotheunembryonated,shelledeggswhichpassintotheenvironment,thefemalescanalsoproduceeggslackingshells(possessingonlyavitellinemembrane),whichbecomeembryonatedwithinthefemale’suterusorintheintestine.Thereleasedlarvaecanre-invadetheintestinalmucosaandcauseinternalautoinfection.Thisprocessmayleadtohyperinfection(amassivenumberofadultworms).HostsWhilepiscivorousbirdshavebeensuggestedasawildlifereservoirofC.philippinensis,thishasnotbeenwellsubstantiatedbasedonfieldobservations.Experimentaltrialshaveestablishedheavypatentinfectionsinseveralbirdspecies(particularlyherons,egrets,andbitterns),butextensivesurveysofwildbirdsinendemicareashavelargelyfailedtodetectinfection. Manyspeciesoffreshwaterfishappearsusceptibletoinfectionandactasintermediatehosts.GeographicDistributionAsthenamesuggests,CapillariaphilippinensisisendemicinthePhilippinesandepidemicshaveoccurredintheNorthernLuzonregion.TheparasiteisalsoendemicinThailand,andsporadiccaseshavebeenreportedfromotherEastandSoutheastAsiancountries. Morerecently,anumberofcas

SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkParasites-Capillariasis(alsoknownasCapillariaInfection)SectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateCapillariasisFAQsMinusRelatedPages OnThisPageWhatiscapillariasis?Howdoesonebecomeinfected?Whereisitfound?Howisitdiagnosed?Canthisbetransmittedhumantohuman?Whatarethesignsandsymptoms?HowcanIpreventcapillariasis?WhatshouldIdoifIthinkIhavecapillariasis?Whatisthetreatment?Whatiscapillariasis?Capillariasisisaparasiticinfectioncausebytwospeciesofnematodes,Capillariahepatica,whichcauseshepaticcapillariasis,andCapillariaphilippinensis,whichcausesintestinalcapillariasis.Therearemedicationsandtreatmentoptionsavailabletocurebothformsofcapillariasis,but,withouttreatment,capillariasiscanleadtodeath.Howdoesonebecomeinfected?C.hepaticaisoftenfoundintheliverofanimalssuchassmallrodents,monkeys,andprairiedogsandcancausecirrhosisintheseanimalhosts.Whentheseanimalsareeatenbylargercarnivores,capillarideggsareingestedandpassedthroughthefecalmatterofthecarnivore.Whenthisfecalmatterisdepositedinthesoil,theseeggsbecomeinfectiveinabout30daysandcaninfectotheranimals,includinghumans.Onceaccidentallyingestedbyahuman,theeggsmigratetotheliverandmaturetoadultworms.Anotherrouteoftransmissionisthroughthedecompositionofinfectedanimalsviaeggsintheliverbeingreleasedintothesoil.C.philippinensisisoftenfoundinthetissuesofsmall,freshwaterfish.Whenhumansingesttheseraworundercookedinfectedfish,larvaemigratetotheintestineandmaturetoadultworms.Femalewormsdepositeggsintheintestine,whicharereleasedinfecalmatter.Wheninfectedhumanfecalmatterreachesfreshwater,fishcanbecomeinfectedandthecyclecontinues.Someeggshatchwithinthehumanintestinecausinghyperinfection(amassivenumberofadultworms).Whereisitfound?InfectionwithC.hepaticaisrarebuthasbeenreportedworldwide.InfectionwithC.philippinensisisfrequentlyfoundinthePhilippinesandThailand.SomecaseshavebeenfoundinotherAsiancountries,theMiddleEast,andColombia.Howisitdiagnosed?C.hepaticacanbediagnose

Capillaria philippinensis is a parasitic nematode which causes intestinal capillariasis. This sometimes fatal disease was first discovered in Northern Luzon ...CapillariaphilippinensisFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchSpeciesofroundwormCapillariaphilippinensisScientificclassificationKingdom:AnimaliaPhylum:NematodaClass:EnopleaOrder:EnoplidaFamily:CapillariidaeGenus:CapillariaSpecies:C. philippinensisBinomialnameCapillariaphilippinensisVelasquez,ChitwoodandSalazar,1968Capillariaphilippinensisisaparasiticnematodewhichcausesintestinalcapillariasis.ThissometimesfataldiseasewasfirstdiscoveredinNorthernLuzon,Philippinesin1964.CaseshavealsobeenreportedfromChina,Egypt,Indonesia,Iran,Japan,Korea,LaoPDR,TaiwanandThailand.[1]CasesdiagnosedinItalyandSpainwerebelievedtobeacquiredabroad,withonecasepossiblycontractedinColombia.[2]ThenaturallifecycleofC.philippinensisisbelievedtoinvolvefishasintermediatehosts,andfish-eatingbirdsasdefinitivehosts.HumansacquireC.philippinensisbyeatingsmallspeciesofinfestedfishwholeandraw.Contents1Discoveryandnomenclature2Hostsandlifecycle3Pathology4Diagnosis5Treatment6ReferencesDiscoveryandnomenclature[edit]Capillariaphilippinensisegg.Betweenthefirstcasereportedin1964andtheendof1967,morethan1000casesweredocumentedinandaroundNorthernLuzonparticularlyatTagudin,IlocosSur,including77deaths.Witchdoctorswerehiredbythelocalstoexorcisethecurseplacedonthembytherivergod,whichtheybelievedwasresponsibleforthissuddendisaster.[3]In1968,thecausewasidentifiedasCapillariaphilippinensis.[4]AdultC.philippinensisareverysmall,withmalesmeasuring1.5-3.9 mmlongand23-28 µmmaximumwidth,whileadultfemalesare2.3-5.3 mmlongand29-47 µmmaximumwidth.Eggsmeasure36-45 µmlongand20 µmwide,andaredescribedaspeanut-shapedwithastriatedshell.ThisspecieshasbeentransferredtothegenusAonchotheca,asAonchothecaphilippinensis,[5]andtothegenusParacapillaria,asParacapillariaphilippinensis.[6]However,thisspeciesisalmostuniversallyreferredtoasCapillariaphilippinensisinthecurr

Capillariasis is a parasitic disease in humans caused by two different species of capillarids: Capillaria hepatica and Capillaria philippinensis.SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkParasites-Capillariasis(alsoknownasCapillariaInfection)SectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateParasites-Capillariasis(alsoknownasCapillariaInfection)MinusRelatedPagesCapillariasisisaparasiticdiseaseinhumanscausedbytwodifferentspeciesofcapillarids:CapillariahepaticaandCapillariaphilippinensis.C.hepaticaistransferredthroughthefecalmatterofinfectedanimalsandcanleadtohepatitis.C.philippinensisistransferredthroughingestinginfectedsmallfreshwaterfishandcanleadtodiarrheaandemaciation.Images:Left:LongitudinalsectionofanadultofC.philippinensisfromanintestinalbiopsyspecimenstainedwithhematoxylinandeosin(H&E)Middle:EggofC.philippinensisinstool.Right:Across-sectionthrougheggsofC.hepaticainlivertissue.(Credit:DPDx)clipboardiconAboutCapillariasisMostcommonquestionsanswered...labiconBiologyStagesofparasitedevelopment...bookiconPublicationsRelatedarticlesandjournalentries…medicaliconResourcesforHealthProfessionalsWhatyouneedtoknow...Pagelastreviewed:September22,2020Contentsource:GlobalHealth,DivisionofParasiticDiseasesandMalariahomeCapillariasisFrequentlyAskedQuestions(FAQs)BiologyplusiconLifeCycleofC.philippinensisLifeCycleofC.hepaticaResourcesforHealthProfessionalsPublicationsAboutOurDivisionSocial_govdgovDGetEmailUpdatesToreceiveemailupdatesaboutthispage,enteryouremailaddress:EmailAddressWhat'sthis?SubmitRelatedLinksParasitesA-ZIndexParasitesGlossaryNeglectedTropicalDiseasesLaboratoryDiagnosticAssistance[DPDx]ContactUsForHealthcareProviders,EmergencyConsultations,andGeneralPublic.ContactUsFacebookTwitterLinkedInSASstatsExitNotification/DisclaimerPolicyCloseLinkswiththisiconindicatethatyouareleavingtheCDCwebsite.TheCentersforDiseaseControlandPrevention(CDC)cannotattesttotheaccuracyofanon-federalwebsite.Linkingtoanon-federalwebsitedoesnotconstituteanen

As the name suggests, Capillaria philippinensis is endemic in the Philippines and epidemics have occurred in the Northern Luzon region. The parasite is also ...SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkParasites-Capillariasis(alsoknownasCapillariaInfection)SectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateBiology-LifeCycleofCapillariaphilippinensisMinusRelatedPagesCausalAgentThenematode(roundworm)Capillaria(=Paracapillaria)philippinensiscauseshumanintestinalcapillariasis.UnlikeC.hepatica,humansaremostlikelythemaindefinitivehost.Transmissionoccursprimarilythrougheatingundercookedfish.LifeCycleViewLargerTypically,unembryonated,thick-shelledeggsarepassedinthehumanstoolandbecomeembryonatedintheexternalenvironmentin5—10days;afteringestionbyfreshwaterfish,larvaehatch,penetratetheintestine,andmigratetothetissues.Ingestionofraworundercookedfishresultsininfectionofthehumanhost.TheadultsofCapillariaphilippinensisareverysmall(males:2.3to3.2mm;females:2.5to4.3mm)andresideinthehumansmallintestine,wheretheyburrowinthemucosa.Inadditiontotheunembryonated,shelledeggswhichpassintotheenvironment,thefemalescanalsoproduceeggslackingshells(possessingonlyavitellinemembrane),whichbecomeembryonatedwithinthefemale’suterusorintheintestine.Thereleasedlarvaecanre-invadetheintestinalmucosaandcauseinternalautoinfection.Thisprocessmayleadtohyperinfection(amassivenumberofadultworms).HostsWhilepiscivorousbirdshavebeensuggestedasawildlifereservoirofC.philippinensis,thishasnotbeenwellsubstantiatedbasedonfieldobservations.Experimentaltrialshaveestablishedheavypatentinfectionsinseveralbirdspecies(particularlyherons,egrets,andbitterns),butextensivesurveysofwildbirdsinendemicareashavelargelyfailedtodetectinfection.Manyspeciesoffreshwaterfishappearsusceptibletoinfectionandactasintermediatehosts.GeographicDistributionAsthenamesuggests,CapillariaphilippinensisisendemicinthePhilippinesandepidemicshaveoccurredintheNorthernLuzonregion.TheparasiteisalsoendemicinThailand,andspor

The nematode (roundworm) Capillaria philippinensis causes human intestinal capillariasis. Two other Capillaria species parasitize animals, ...Thispageusesframes,butyourbrowserdoesn'tsupportthem.

In July 1988. a case of human infection with Capillaria philippinensis, so-called the intestinal capillariasis, was discovered at the National Taiwan ...HomeAboutCDCPublicationsPeriodicalsTaiwanEpidemiologyBulletinOriginalArticlePeriodicalsPeriodicalsTaiwanEpidemiologyBulletinTaiwanEpidemiologyBulletinTaiwanEpidemiologyBulletinAboutTaiwanEBAboutTaiwanEBAboutTaiwanEBIntroductionInformationforauthorsErratumVolumeIssueOriginalArticleOutbreakInvestigationDiseaseSurveillanceCDCAnnualReportStatisticsofcommunicablediseasesandsurveillancereportinTaiwanareaStatisticsofcommunicablediseasesandsurveillancereportTaiwanTuberculosisControlReportOriginalArticleFacebookLinePrintBackCasereportofhumaninfectionwithCapillariaphilippinensisChing-YuChen1989Vol.5NO.12CorrespondenceAuthor：AuthorAffiliationsAbstract：InJuly1988.acaseofhumaninfectionwithCapillariaphilippinensis,so-calledtheintestinalcapillariasis,wasdiscoveredattheNationalTaiwanUniversityHospital(NTUH).ThisisthefirstcasereportedinTaiwan.AttachedFiles：?93CasereportofhumaninfectionwithCapillariaphilippinensis.pdf(opennewtab):::SitemapPrivacyPolicySecurityPolicyGovernmentWebsiteOpenInformationAnnouncementDirector-mailCopyrightNoticeonHealthEducationalMaterialsTaiwanCentersforDiseaseControlNo.6,LinsenS.Rd.,JhongjhengDistrict,TaipeiCity10050,Taiwan(R.O.C.)MAPTEL：886-2-2395-9825Copyright©2019TaiwanCentersforDiseaseControl.Allrightsreserved.

Fish from lagoons in Northern Luzon, Philippines, have been shown experimentally to be intermediate hosts of Capillaria philippinensis.Clipboard,SearchHistory,andseveralotheradvancedfeaturesaretemporarilyunavailable.SkiptomainpagecontentCOVID-19InformationPublichealthinformation(CDC)Researchinformation(NIH)SARS-CoV-2data(NCBI)Preventionandtreatmentinformation(HHS)Español AccesskeysNCBIHomepageMyNCBIHomepageMainContentMainNavigationSearch:SearchAdvancedClipboardUserGuideSaveEmailSendtoClipboardMyBibliographyCollectionsCitationmanagerDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSavecitationtofileFormat:Summary(text)PubMedPMIDAbstract(text)CSVCreatefileCancelEmailcitationSubject:1selecteditem:1822876-PubMedTo:Format:SummarySummary(text)AbstractAbstract(text)MeSHandotherdataSendemailCancelAddtoCollectionsCreateanewcollectionAddtoanexistingcollectionNameyourcollection:Namemustbelessthan100charactersChooseacollection:UnabletoloadyourcollectionduetoanerrorPleasetryagainAddCancelAddtoMyBibliographyMyBibliographyUnabletoloadyourdelegatesduetoanerrorPleasetryagainAddCancelYoursavedsearchNameofsavedsearch:Searchterms:TestsearchtermsWouldyoulikeemailupdatesofnewsearchresults?SavedSearchAlertRadioButtonsYesNoEmail:(change)Frequency:MonthlyWeeklyDailyWhichday?ThefirstSundayThefirstMondayThefirstTuesdayThefirstWednesdayThefirstThursdayThefirstFridayThefirstSaturdayThefirstdayThefirstweekdayWhichday?SundayMondayTuesdayWednesdayThursdayFridaySaturdayReportformat:SummarySummary(text)AbstractAbstract(text)PubMedSendatmost:1item5items10items20items50items100items200itemsSendevenwhentherearen'tanynewresultsOptionaltextinemail:SaveCancelCreateafileforexternalcitationmanagementsoftwareCreatefileCancelYourRSSFeedNameofRSSFeed:Numberofitemsdisplayed:510152050100CreateRSSCancelRSSLinkCopyActionsCiteFavoritesDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSharePermalinkCopyPagenavigationTitle&authorsAbstractSimilararticlesCitedbyMeSHtermsRelatedinformationLinkOut-moreresourcesTitle