Laser therapy for twin-twin transfusion syndrome offers best outcomes | Twin twin transfusion syndrome medscape
COVID-19:Advice,updatesandvaccineoptionsWeareopenforsafein-personcare.Learnmore:MayoClinicfactsaboutcoronavirusdisease2019(COVID-19)OurCOVID-19patientandvisitorguidelines,plustrustedhealthinformationLateston COVID-19vaccination bysite:ArizonapatientvaccinationupdatesArizona,FloridapatientvaccinationupdatesFlorida,RochesterpatientvaccinationupdatesRochesterandMayoClinicHealthSystempatientvaccinationupdatesMCHSSkiptositenavigationSkiptoContentThiscontentdoesnothaveanEnglishversion.ThiscontentdoesnothaveanArabicversion.ReferralsNewsVideosPhysiciansContinuingEducationExternalLinkClinicalTrialsLasertherapyfortwin-twintransfusionsyndromeoffersbestoutcomesMarch19,2021Twin-twintransfusionsyndrome(TTTS)isarareyetseriouscondition,requiringfetalinterventiontopreventlossofoneorbothfetuses.MayoClinicisoneofahandfulofmedicalcenterstreatingthisconditionnationwide.TTTSincidence,staging,risksanddetectionTTTSisrare—about4,500casesintheU.S.yearly,orabout15%ofmonochorionictwins—accordingtotheTwintoTwinTransfusionSyndromeFoundation.Vascularcommunicationispresentvirtuallyinallmonochorionictwins;inmostcases,thebloodflowisbalancedwithnonettransfusionofbloodfromonetwintotheother.IncaseswithTTTS,however,thebloodflowthroughtheseanastomosesisunbalanced,andanetamountofbloodisslowlytransfused,saysMauroH.Schenone,M.D.,chairofMaternalandFetalMedicineandamaternalfetalmedicinespecialistatMayoClinic'scampusinRochester,Minnesota.Ifunaddressed,onefetusbecomeshypovolemicandtheotherbecomeshypervolemic.Hypovolemiacausesadecreaseintheurineoutputleadingtooligohydramniosoranhydramnios,whilehypervolemiaintherecipienttwincausesanincreaseintheurineoutputthatleadstopolyhydramnios.Thesefindingsinultrasounddefinetwin-twintransfusionsyndrome.Basedontheseverity,TTTSisclassifiedinfivestages:Instage1,thereisoligohydramniosandpolyhydramnios.Atstage2,thedonortwin'sbladderisnotvisible.Progressiontostage3involvesfurtherhemodynamicchanges,noticeablewithDopplerexamination.Atthisstage,thesituationiscriticalandheartfailuremay
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