twin-to-twin transfusion syndrome (TTTS) | Twin twin transfusion syndrome medscape
ColoradoFetalCareCenterTwin-to-TwinTransfusionSyndrome(TTTS)Weseemore,treatmoreandhealmorekidsthananyotherhospitalintheregion.NextStepsNextStepsWouldyouliketolearnmoreaboutus?ColoradoFetalCareCenterDoyouhavequestionsaboutthiscondition?720-777-4463Wantasecondopinion?GetstartedWhatistwin-to-twintransfusionsyndrome(TTTS)?Twin-to-twintransfusionsyndrome(TTTS)isadisorderthataffectsidenticaltwinpregnancies.Itcanoccurwhentwofetusesshareaplacenta(referredtoasamonochorionictwinpregnancy)becausethereisn’tabarrierseparatingthetwofetusesfromeachother.Sometimes,bloodvesselsfromthetwins'umbilicalcordsformabnormalconnectionswithintheirsharedspace,connectingonebabytotheother.Whenthishappens,bloodflowsunevenlybetweenthebabiesandtheircirculationsbecomeunbalanced.Thisputsthetwinsatriskforearlydelivery,neurologicaldamageandmore.Twin-to-twintransfusionsyndrome(TTTS)isaserious,rareconditiononlyseeninidenticaltwinswhoshareaplacenta(monochorionic).Onefetus(calledthe"donor"twin)"donates"theircirculationoffluidandbloodtotheotherfetus(knownasthe"recipient").Asaresult,thedonortwinmaystopproducingurineanditsamnioticsacbecomesmuchsmaller.Therecipienttwinreceivestoomuchbloodandurineandproducesmoreamnioticfluid,resultinginhavingaverylargeamnioticsac.TTTScanleadtoseverecomplicationsforthetwins.That'swhyearlydetectioniscriticaltohelpimproveoutcomesforbothbabiesandtheirmother.WhatcausesTTTSinpregnancy?TheexactcauseofTTTSisnotwellunderstood;therearenoknowngeneticcausesofTTTS,andthere'snothingamotherdidtocauseit.Inthemajorityofcases,TTTSdevelopsinthesecondtrimesterofpregnancy.Whilethere'snothinganyonecandotopreventTTTS,there'splentywecandotohelpyourbabies.Theimportantthingthatfamiliescandowhentheyarediagnosedwithmonochorionic-diamniotictwinsistohavecloseandearlysurveillanceforTTTS,specificallybyhavingultrasoundseverytwoweeksstartingat16weeksofgestation.WhogetsTTTS?TTTScanaffectidenticaltwinsbeforetheyareborn.Approximately1inevery250pregnanciesareidenticalormonochorionicandapproximately2outof3ofthesepre
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