Is the probability of having twins determined by genetics? | Twin gene

The likelihood of conceiving twins is a complex trait. It is probably affected by multiple genetic and environmental factors, depending on ...YouAreHere:Home→Genetics→HelpMeUnderstandGenetics→GeneticsandHumanTraits→Istheprobabilityofhavingtwinsdeterminedbygenetics?URLofthispage:https://medlineplus.gov/genetics/understanding/traits/twins/Istheprobabilityofhavingtwinsdeterminedbygenetics?FromGeneticsHomeReference.LearnmoreThelikelihoodofconceivingtwinsisacomplextrait.Itisprobablyaffectedbymultiplegeneticandenvironmentalfactors,dependingonthetypeoftwins.Thetwotypesoftwinsareclassifiedasmonozygoticanddizygotic.Monozygotic(MZ)twins,alsocalledidenticaltwins,occurwhenasingleeggcellisfertilizedbyasinglespermcell.Theresultingzygotesplitsintotwoveryearlyindevelopment,leadingtotheformationoftwoseparateembryos.MZtwinsoccurin3to4per1,000birthsworldwide.ResearchsuggeststhatmostcasesofMZtwinningarenotcausedbygeneticfactors.However,afewfamilieswithalarger-than-expectednumberofMZtwinshavebeenreported,whichindicatesthatgeneticsmayplayarole.Itispossiblethatgenesinvolvedinstickingcellstogether(celladhesion)maycontributetoMZtwinning,althoughthishypothesishasnotbeenconfirmed.Mostofthetime,thecauseofMZtwinningisunknown.Dizygotic(DZ)twins,alsocalledfraternaltwins,occurwhentwoeggcellsareeachfertilizedbyadifferentspermcellinthesamemenstrualcycle.DZtwinsareabouttwiceascommonasMZtwins,andtheyaremuchmorelikelytoruninfamilies.Comparedwiththegeneralpopulation,womenwithamotherorsisterwhohavehadDZtwinsareabouttwiceaslikelytohaveDZtwinsthemselves.DZtwinningisthoughttobearesultofhyperovulation,whichisthereleaseofmorethanoneegginasinglemenstrualcycle.ToexplainhowDZtwinningcanruninfamilies,researchershavelookedforgeneticfactorsthatincreasethechanceofhyperovulation.However,studiesexaminingthecontributionsofspecificgeneshavehadmixedandconflictingresults.FewspecificgenesinhumanshavebeendefinitivelylinkedwithhyperovulationoranincreasedprobabilityofDZtwinning.OtherfactorsknowntoinfluencethechanceofhavingDZt

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