Secondary amenorrhea refers to the absence of three or more periods in a row by someone who has had periods in the past. Pregnancy is the ...Scheduleyourappointmentnowforsafein-personcare.Learnmore:MayoClinicfactsaboutcoronavirusdisease2019(COVID-19)Our COVID-19patient andvisitorguidelines,plustrustedhealthinformationLateston COVID-19vaccination bysite:ArizonapatientvaccinationupdatesArizona,FloridapatientvaccinationupdatesFlorida,RochesterpatientvaccinationupdatesRochesterandMayoClinicHealthSystempatientvaccinationupdatesMCHSSkiptositenavigationSkiptoContentThiscontentdoesnothaveanEnglishversion.ThiscontentdoesnothaveanArabicversion.SectionsforAmenorrheaSymptoms&causesDiagnosis&treatmentDoctors&departmentsPrintOverviewAmenorrhea(uh-men-o-REE-uh)istheabsenceofmenstruation,oftendefinedasmissingoneormoremenstrualperiods.Primaryamenorrheareferstotheabsenceofmenstruationinsomeonewhohasnothadaperiodbyage15.Themostcommoncausesofprimaryamenorrhearelatetohormonelevels,althoughanatomicalproblemsalsocancauseamenorrhea.Secondaryamenorrheareferstotheabsenceofthreeormoreperiodsinarowbysomeonewhohashadperiodsinthepast.Pregnancyisthemostcommoncauseofsecondaryamenorrhea,althoughproblemswithhormonesalsocancausesecondaryamenorrhea.Treatmentofamenorrheadependsontheunderlyingcause.Products&ServicesBook:MayoClinicFamilyHealthBook,5thEditionNewsletter:MayoClinicHealthLetter—DigitalEditionShowmoreproductsfromMayoClinicSymptomsDependingonthecauseofamenorrhea,youmightexperienceothersignsorsymptomsalongwiththeabsenceofperiods,suchas:MilkynippledischargeHairlossHeadacheVisionchangesExcessfacialhairPelvicpainAcneWhentoseeadoctorConsultyourdoctorifyou'vemissedatleastthreemenstrualperiodsinarow,orifyou'veneverhadamenstrualperiodandyou'reage15orolder.RequestanAppointmentatMayoClinicCausesFemalereproductivesystemOpenpop-updialogboxCloseFemalereproductivesystemFemalereproductivesystemTheovaries,fallopiantubes,uterus,cervixandvagina(vaginalcanal)makeupthefemalereproductivesystem.Amenorrheacanoccurfo