However, one study reported poor predictive power of unawareness for memory decline in detecting MCI individuals who progressed to dementia 2 ...ThisarticleispartoftheResearchTopic“Weknowwhatweare,butknownotwhatwemaybe”:MetacognitionandSelf-awarenessintheAgingBrainViewall7ArticlesArticlesSergioStarksteinUniversityofWesternAustralia,AustraliaGianfrancoSpallettaSantaLuciaFoundation(IRCCS),ItalyMARIADONATAORFEIIMTSchoolforAdvancedStudiesLucca,ItalyTheeditorandreviewers'affiliationsarethelatestprovidedontheirLoopresearchprofilesandmaynotreflecttheirsituationatthetimeofreview.AbstractIntroductionMaterialsandMethodsResultsDiscussionDataAvailabilityStatementEthicsStatementAuthorContributionsFundingConflictofInterestAcknowledgmentsFootnotesReferencesSuggestaResearchTopic>DownloadArticleDownloadPDFReadCubeEPUBXML(NLM)SupplementaryMaterialExportcitationEndNoteReferenceManagerSimpleTEXTfileBibTextotalviewsViewArticleImpactSuggestaResearchTopic>SHAREONOpenSupplementalDataORIGINALRESEARCHarticleFront.Psychiatry,31March2021|https://doi.org/10.3389/fpsyt.2021.631518AnosognosiainMildCognitiveImpairment:LackofAwarenessofMemoryDifficultiesCharacterizesProdromalAlzheimer'sDiseaseChristineBastin1,2*,FabriceGiacomelli1,FrédéricMiévis1,ChristianLemaire1,BénédicteGuillaume3andEricSalmon1,41GIGA-CyclotronResearchCenter-invivoImaging,UniversityofLiège,Liège,Belgium2F.R.S.-FondsNationaldelaRechercheScientifique,Bruxelles,Belgium3CenterHospitalierduBoisdel'AbbayeetdeHesbaye,Liège,Belgium4MemoryClinic,CHULiège,Liège,BelgiumWhileanosognosiaisoftenpresentinAlzheimer'sdisease,thedegreeofawarenessofcognitivedifficultiesintheearlierstages,suchasMildCognitiveImpairment(MCI),islessclear.UsingaquestionnaireandFeeling-of-Knowingtasks,theaimsofthisstudywere(1)totestthehypothesisthatanosognosiaispresentspecificallyinprodromalADstageinpatientsthat,owingtoamoresevereADneuropathology,willrapidlyprogresstoovertdementiaand(2)toassesstheneuralbasesofself-awarenessformemoryfunctioning.Agroupof44patientswithamne