Vulval intraepithelial neoplasia (VIN). Vulval intraepithelial neoplasia (VIN) is a skin condition of the vulva. The vulva is the area between a ...SkiptomaincontentHomeAboutCancerVulvalcancerStages,typesandgradesVulvalintraepithelialneoplasia(VIN)Vulvalintraepithelialneoplasia(VIN)isaskinconditionofthevulva.Thevulvaistheareabetweenawoman’slegsthatincludesthefemaleexternalsexorgans.DiagramshowingthevulvaAbnormalcellsdevelopinthesurfacelayersoftheskincoveringthevulva.Itisnotvulvalcancerbutcould turnintoacancer.Thismaytakemanyyears.SomedoctorscallitprecanceralthoughmanywomenwithVINwillnotdevelopcancer.VINstandsfor:Vulval-youcangetVINanywhereonthevulvaandyoumayhaveitinmorethanoneplace Intraepithelial-theabnormalcellsarecontainedwithinthetoplayerofskin(epidermis)thatcoversthevulvaNeoplasia-thecellsintheskinareabnormal TypesofVINThereare3typesofVIN:lowgradesquamousintraepitheliallesion(LSIL)highgradesquamousintraepitheliallesion(HSIL)differentiatedVIN(dVIN)YoumayalsohearthetermsVIN1,VIN2,orVIN3.Thisishowdoctorsusedtoclassifyvulvalintraepithelialneoplasia.ThegradesVIN1,VIN2,andVIN3refertohowdeeplytheabnormalcellsgointothesurfacelayeroftheskin.Iftheabnormalcellsbreakthroughthebasementmembraneintothedeepertissue,itisclassedasvulvalcancer.Highgradesquamousintraepitheliallesion(HSIL)ThisisthemostcommontypeofVIN.ManywomenwhohaveithaveongoinginfectionswithhighrisktypesofHPV. Itoccursmainlyinwomenaged35to49andismorecommoninwomenwhosmokeorhaveaweakimmunesystem. VIN2andVIN3isnowcalledhighgradesquamousintraepitheliallesion(HSIL). Youusuallyhavetreatmentforhighgradesquamousintraepitheliallesion(HSIL).Thisisbecausethereisariskthattheabnormalcellsmaydevelopintocancerovertime.Buttheriskislow.  Lowgradesquamousintraepitheliallesion(LSIL)VIN1isnowcalledlowgradesquamousintraepitheliallesion(LSIL).LSILisgenerallyamildabnormality.Itisusuallycausedbylowrisktypesofthehumanpapillomavirus(HPV).Theselowrisktypes cancausewartsinthisarea.Theyarenotcancerousandusuallygoawaywithouttreatment.Youmayha