Marburg virus is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. Marburg ...MarburgvirusFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchSpeciesofvirusForthegenus,seeMarburgvirus.MarburgvirusTransmissionelectronmicrographofMarburgvirusVirusclassification(unranked):VirusRealm:RiboviriaKingdom:OrthornaviraePhylum:NegarnaviricotaClass:MonjiviricetesOrder:MononegaviralesFamily:FiloviridaeGenus:MarburgvirusSpecies:MarburgmarburgvirusVirus:MarburgvirusMarburgvirus[1]isahemorrhagicfevervirusoftheFiloviridaefamilyofvirusesandamemberofthespeciesMarburgmarburgvirus,genusMarburgvirus.Marburgvirus(MARV)causesMarburgvirusdiseaseinhumansandnonhumanprimates,aformofviralhemorrhagicfever.[2]Thevirusisconsideredtobeextremelydangerous.TheWorldHealthOrganization(WHO)ratesitasaRiskGroup4Pathogen(requiringbiosafetylevel4-equivalentcontainment).[3]IntheUnitedStates,theNIH/NationalInstituteofAllergyandInfectiousDiseasesranksitasaCategoryAPriorityPathogen[4]andtheCentersforDiseaseControlandPreventionlistsitasaCategoryABioterrorismAgent.[5]ItisalsolistedasabiologicalagentforexportcontrolbytheAustraliaGroup.[6]Theviruscanbetransmittedbyexposuretoonespeciesoffruitbatsoritcanbetransmittedbetweenpeopleviabodyfluidsthroughunprotectedsexandbrokenskin.Thediseasecancausebleeding(haemorrhage),fever,andothersymptomssimilartoEbola.However,MarburgvirusisnotthesameasEbola,althoughsimilar.Actualtreatmentofthevirusafterinfectionisnotpossible,butearly,professionaltreatmentofsymptomslikedehydrationconsiderablyincreasessurvivalchances.[7]In2009,expandedclinicaltrialsofanEbolaandMarburgvaccinebeganinKampala,Uganda.[8][9]Contents1History1.1Discovery1.2Nomenclature2Virology2.1Genome2.2Structure2.3Entry2.4Replication3Ecology4Evolution5Humandisease5.1Recordedoutbreaks6Prevention7Biologicalweapon8References9Furtherreading10ExternallinksHistory[edit]Discovery[edit]CryoEMreconstructionofasectionoftheMarburgvirusnucleocaps