Shigella sonnei is the emerging pathogen globally, as it is the second common infectious species of shigellosis (bloody diarrhoea) in low- and ...NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutJournalListNaturePublicHealthEmergencyCollectionPMC7489455ArchMicrobiol.2020Sep14:1–14.doi: 10.1007/s00203-020-02034-3[Epubaheadofprint]PMCID:PMC7489455PMID:32929595Shigellasonnei:virulenceandantibioticresistanceAhteshamAhmadShad1andWajahatAhmedShad2AhteshamAhmadShad1InstituteofMicrobiology,UniversityofAgriculture,Faisalabad,38040PakistanFindarticlesbyAhteshamAhmadShadWajahatAhmedShad2DepartmentofBiochemistry,UniversityofAgriculture,Faisalabad,PakistanFindarticlesbyWajahatAhmedShadAuthorinformationArticlenotesCopyrightandLicenseinformationDisclaimer1InstituteofMicrobiology,UniversityofAgriculture,Faisalabad,38040Pakistan2DepartmentofBiochemistry,UniversityofAgriculture,Faisalabad,PakistanAhteshamAhmadShad,Email:moc.oohay@dahsa.mahsetha.Correspondingauthor.CommunicatedbyCommunicatedbyErkostackebrandt.Received2020Jun24;Revised2020Aug27;Accepted2020Sep2.Copyright©Springer-VerlagGmbHGermany,partofSpringerNature2020ThisarticleismadeavailableviathePMCOpenAccessSubsetforunrestrictedresearchre-useandsecondaryanalysisinanyformorbyanymeanswithacknowledgementoftheoriginalsource.ThesepermissionsaregrantedforthedurationoftheWorldHealthOrganization(WHO)declarationofCOVID-19asaglobalpandemic.Shigellasonneiistheemergingpathogenglobally,asitisthesecondcommoninfectiousspeciesofshigellosis(bloodydiarrhoea)inlow-andmiddle-incomecountries(LMICs)andtheleadingoneindevelopedworld.ThemultifactorialprocessesandnovelmechanismshavebeenidentifiedinS.sonnei,thatarecollectivelyplayingapartasubstantialroleinincreasingitsprevalence,whilereplacingtheS.flexneriandotherGram-negativegutpathogensnicheoccupancy.Recently,studiessuggestthatduetoimprovementinsanitationS.sonneihasreducedcross-immunizationfromPlesiomonasshigelliodes(havingsameO-antigenasS.sonnei)andalsofou