Symptomatic relief of epididymitis involves the use of nonpharmacologic and adjunctive therapies. Recommendations include bed rest, cold ...PharmacyPracticeAffordableMedicinesComplianceCompoundingDrugApprovalsGeriatricsHospital/HealthSystemIn-PharmacyVaccinesLawMedicationManagementNews&TrendsOTCSpecialtyPharmacyTechnologyDiseaseStateAllergyAutoimmuneBreastCancerCardiovascularCold&FluDermatologyDiabetesGastroenterologyHematologyHIV/AIDSInfectiousDiseaseLungCancerMentalHealthNeurologyOncologyOphthalmologyOrthopedicsPainManagementPediatricsRespiratoryUrology/NephrologyWomen’sHealthVideosPatientTeachingAidPublicationsFeaturedIssueFeaturedSupplementsConferenceCoverageContinuingEducationSubscribeCOVID-19ResourcesUSPharm.2015;40(8):39-43.ABSTRACT:Epididymitis,aninflammationofthetubefoundposteriortothetesticle,accountsforasignificantnumberofphysicianofficevisitsannually.Mendiagnosedwithepididymitisaretypicallybetweentheagesof18and35yearsandpresentwithagradualonsetofscrotalpainaswellassymptomsmimickingurinarytractinfection.Whiletheconditionisoftenaresultofsexualactivity,otherriskfactorsmayincludeprolongedsitting,bicycleormotorcycleriding,prostaticobstruction,andcertainmedications.EmpiricalantibiotictherapyshouldcoverChlamydiatrachomatis,Neisseriagonorrhoeae,andEscherichiacoli,themostcommoninfectingpathogens.Pharmacistsmayprovideconsultationonappropriateantibiotictherapyanddosing.Genitourinaryissuesaccountforasignificantnumberofvisitstooutpatientprimarycareofficesandemergencyroomseachyear.Oftheseconditions,epididymitis—inflammationoftheepididymis(thetubeposteriortothetesticlethatcarriesandstoressperm)—constitutesmorethan600,000diagnosesofmenbetweentheagesof18and35yearsannuallyintheUnitedStates.1,2Althoughnoestablishedmeasurehasbeendocumented,thesocioeconomicimpactofepididymitisissuggestedtobesubstantialgiventhatthisconditionoftenoccursduringaman’smostproductiveyearsoflife.3Ongoingsymptomsofordamageresultingfromepididymitis,includinginfertility,cangreatlyimpactapatient’squalit