ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointEdition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSLogInSignUpIt'sFree!Edition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSRegisterLogInNoResultsNoResultsForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointclosePleaseconfirmthatyouwouldliketologoutofMedscape.Ifyoulogout,youwillberequiredtoenteryourusernameandpasswordthenexttimeyouvisit.LogoutCancelhttps://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxMzA4MC1tZWRpY2F0aW9uprocessing....Drugs&Diseases>OphthalmologyHordeolum MedicationUpdated:Feb12,2021Author:MichaelPEhrenhaus,MD;ChiefEditor:EdselBIng,MD,MPH,FRCSC,PhD,MA more...ShareEmailPrintFeedbackCloseFacebookTwitterLinkedInGoogle+SectionsHordeolumSectionsHordeolumOverviewBackgroundPathophysiologyEpidemiologyShowAllPresentationHistoryPhysicalCausesShowAllDDxWorkupLaboratoryStudiesHistologicFindingsShowAllTreatmentMedicalCareSurgicalCareShowAllMedicationMedicationSummaryAntibioticsShowAllFollow-upFurtherOutpatientCareDeterrence/PreventionComplicationsPrognosisPatientEducationShowAllQuestions&AnswersReferencesMedicationMedicationSummaryThegoalsofpharmacotherapyaretotreattheinfection,toreducemorbidity,andtopreventcomplications.Next:AntibioticsClassSummaryAcourseoforalantibioticsisindicatedifthehordeolumiscomplicatedbypreseptalcellulitis.Cephalexin(Keflex)ViewfulldruginformationFirst-generationcephalosporinoftenusedinskinorskinstructureinfections(eg,acutehordeolum)causedbystaphylococciorstreptococci.Administeredorallyandhasahalf-lifeof50-80min.Only10%isproteinboundandgreaterthan90%recoveredunchangedinurine.Erythromycinbase(Ery-Tab,PCE,E.E.S.400)ViewfulldruginformationInhibitsbacterialgrowth,possiblybyblockingdissociationofpeptidylt-RNAfromribosomes,causingRNA-dependentproteinsynthesistoarrest.Indicatedforinfectionscausedbysusceptiblestrainsofmicroorganismsandforpreventionofcornealandconjunctiv