The traditional second-line agent for uterine atony has been ergonovine (or ergotrate) given as an initial dose of 100 or 125 mcg intravenously or intramyometrially ...ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoSpecialty:MultispecialtyAllergy&ImmunologyAnesthesiologyBusinessofMedicineCardiologyCriticalCareDermatologyDiabetes&EndocrinologyEmergencyMedicineFamilyMedicineGastroenterologyGeneralSurgeryHematology-OncologyHIV/AIDSHospitalMedicineInfectiousDiseasesInternalMedicineMultispecialtyNephrologyNeurologyOb/Gyn&Women'sHealthOncologyOphthalmologyOrthopedicsPathology&LabMedicinePediatricsPlasticSurgeryPsychiatryPublicHealthPulmonaryMedicineRadiologyRheumatologyTransplantationUrologyMedicalStudentsNursesPharmacistsResidentsTodayonMedscapeEdition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSLogInSignUpIt'sFree!Edition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSRegisterLogInNoResultsNoResultsThursday,March25,2021ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoclosePleaseconfirmthatyouwouldliketologoutofMedscape.Ifyoulogout,youwillberequiredtoenteryourusernameandpasswordthenexttimeyouvisit.LogoutCancelhttps://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL2Fuc3dlcnMvMjc1MDM4LTE4NzU2Mi9ob3ctaXMtdXRlcmluZS1hdG9ueS1yZWxhdGVkLXBvc3RwYXJ0dW0taGVtb3JyaGFnZS1wcGgtdHJlYXRlZA==processing....Drugs&Diseases>Obstetrics&Gynecology>PostpartumHemorrhageQ&AHowisuterineatony-relatedpostpartumhemorrhage(PPH)treated?Updated:Jun27,2018Author:JohnRSmith,MD,FACOG,FRCSC;ChiefEditor:RonaldMRamus,MD more...ReferencesShareEmailPrintFeedbackCloseFacebookTwitterLinkedInGoogle+AnswerTwowell-designedtrialsindicatethatoxytocinshouldbethedrugofchoiceforbothprophylaxisandtreatmentofpostpartumhemorrhagecausedbyuterineatony.[42]Assessuterinesizeandtonebyplacingahandontheuterinefundusandmassagingtheuterus,whichservestoexpressanyclotsthathaveaccumulatedintheuterusorvagina.Iftheuterusisfoundtobeboggyandnotwellcontracte