The purpose of this randomized clinical trial is to evaluate the effect of eyelid hygiene on subjective symptoms, anterior blepharitis, and ...SkiptomaincontentThankyouforvisitingnature.com.YouareusingabrowserversionwithlimitedsupportforCSS.Toobtainthebestexperience,werecommendyouuseamoreuptodatebrowser(orturnoffcompatibilitymodeinInternetExplorer).Inthemeantime,toensurecontinuedsupport,wearedisplayingthesitewithoutstylesandJavaScript.AdvertisementnaturescientificreportsarticlesarticleClinicalefficacyofeyelidhygieneinblepharitisandmeibomianglanddysfunctionaftercataractsurgery:arandomizedcontrolledpilottrialDownloadPDFSubjectsEyediseasesMedicalresearchOutcomesresearchClinicaltrialdesignAbstractThepurposeofthisrandomizedclinicaltrialistoevaluatetheeffectofeyelidhygieneonsubjectivesymptoms,anteriorblepharitis,andmeibomianglanddysfunction(MGD)aftercataractsurgery.SubjectswithobstructiveMGDwhounderwentcataractsurgerywererandomlydividedintotwogroups.Intheeyelidhygienegroup,eyelidhygienewasperformedtwiceadayfor10 daysfrom3 daysbeforeto1 weekaftercataractsurgery.Thecontrolgroupdidnotperformeyelidhygiene.AsubjectivesymptomquestionnaireofSPEED,anteriorblepharitisgrade,andmeibumqualityandquantitywasevaluatedatbaselineandatpostoperative1and4 weeks.Theeyelidhygienegroup(n = 36)showeddecreasedSPEEDscoreaftercataractsurgeryandthecontrolgroup(n = 33)didnot.Anteriorblepharitisgradewasworse1 weekaftersurgeryinthecontrolgroupbutnotintheeyelidhygienegroup.Thecontrolgrouphadsignificantlydecreasedmeibumqualityandquantityinboththeupperandlowereyelidsaftercataractsurgery,buttheeyelidhygienegroupdidnot.Eyelidhygienebefore/aftercataractsurgeryimprovedpostoperativesubjectivesymptomsandpreventedpostoperativeexacerbationofanteriorblepharitisandMGD.Thus,perioperativeeyelidhygieneisrecommendedforpatientswithobstructiveMGDwhoundergocataractsurgery.DownloadPDFIntroductionBlepharitisisdividedintoanteriorandposteriorblepharitisaccordingtoanatomiclocation.Meibomianglanddysfunction(MGD)isthemaincauseof