Briefly, it was known as Chlamydophila pneumoniae, and that name is used as an alternate in some sources. In some cases, to avoid confusion, both names are ...ChlamydiapneumoniaeFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchSpeciesofbacteriumChlamydiapneumoniaeScientificclassificationKingdom:BacteriaPhylum:ChlamydiaeOrder:ChlamydialesFamily:ChlamydiaceaeGenus:ChlamydiaSpecies:C. pneumoniae[1]ChlamydiapneumoniaeisaspeciesofChlamydia,anobligateintracellularbacterium[2]thatinfectshumansandisamajorcauseofpneumonia.ItwasknownastheTaiwanacuterespiratoryagent(TWAR)fromthenamesofthetwooriginalisolates –Taiwan(TW-183)andanacuterespiratoryisolatedesignatedAR-39.[3]Briefly,itwasknownasChlamydophilapneumoniae,andthatnameisusedasanalternateinsomesources.[4]Insomecases,toavoidconfusion,bothnamesaregiven.[5]C.pneumoniaehasacomplexlifecycleandmustinfectanothercelltoreproduce;thus,itisclassifiedasanobligateintracellularpathogen.ThefullgenomesequenceforC.pneumoniaewaspublishedin1999.[6]Italsoinfectsandcausesdiseaseinkoalas,emeraldtreeboas(Coralluscaninus),iguanas,chameleons,frogs,andturtles.ThefirstknowncaseofinfectionwithC.pneumoniaewasacaseofconjunctivitisinTaiwanin1950.TherearenoknowncasesofC.pneumoniaeinhumanhistorybefore1950.Thisatypicalbacteriumcommonlycausespharyngitis,bronchitis,coronaryarterydiseaseandatypicalpneumoniainadditiontoseveralotherpossiblediseases.[7][8]MicrographofChlamydiapneumoniaeinanepithelialcellinacutebronchitis:1 –infectedepitheliocyte,2 –uninfectedepitheliocytes,3 –chlamydialinclusionbodiesincell,4 –cellnucleiContents1Lifecycleandmethodofinfection2Diseases3Vaccineresearch4References5ExternallinksLifecycleandmethodofinfection[edit]LifecycleofChlamydiapneumoniae.A—Chlamydiaelementarybody.B—Lungcell.2—Chlamydiaentersthecell.3—Elementarybodybecomesareticulatebody.4—Replication.5—Reticulatebodiesbecomeelementarybodiesandarereleasedtoinfectothercells.[citationneeded]Chlamydiapneumoniaeisasmallgram-negativebacterium(0.2to1μm)thatundergoesseveraltr