What Is the Survival Rate of Cholangiocarcinoma? | Cholangiocarcinoma - uptodate
homecancercenterTopicGuideWhatIstheSurvivalRateofCholangiocarcinoma?MedicalAuthor:JohnP.Cunha,DO,FACOEPReviewedon12/30/2020DefinitionWhatIsCholangiocarcinoma?CausesWhatCausesCholangiocarcinoma?DiagnosisHowIsCholangiocarcinomaDiagnosed?TreatmentWhatIstheTreatmentforCholangiocarcinoma?PrognosisWhatIstheLifeExpectancyforCholangiocarcinoma?GuideWhatIstheSurvivalRateofCholangiocarcinoma?TopicGuideWhatIsCholangiocarcinoma?Cholangiocarcinoma(bileductcancer)isadeadlydisease.Evenwhenit’sdetectedearly,thefiveyearsurvivalratesforpeoplewiththiscancerislessthan25%.Cholangiocarcinoma(bileductcancer)isararecancerthatoccurswhencellsinabileductgrowabnormallyandoutofcontrol. WhatAreSymptomsofCholangiocarcinoma?Cholangiocarcinoma(bileductcancer)oftendoesnotcausesymptomsearlyonandthecancerisoftenfoundinlaterstages. Whensymptomsofcholangiocarcinomadooccur,theymayinclude:Yellowskinandeyes(jaundice)(mostcommonsymptom)ItchingLight-colored/greasystoolsDarkurineAbdominalpainLossofappetiteWeightlossFeverNausea VomitingCholangiocarcinomaisrare.Thesesymptomsaremorelikelytobecausedbysomethingotherthancholangiocarcinoma.WhatCausesCholangiocarcinoma?Theexactcauseofcholangiocarcinoma(bileductcancer)isunknownbutitisbelievedtobeduetogeneticchanges. Riskfactorsfordevelopingcholangiocarcinomainclude: CertaindiseasesoftheliverorbileductsPrimarysclerosingcholangitis(PSC)BileductstonesCholedochalcystdiseaseLiverflukeinfectionsAbnormalitieswherethebileductandpancreaticductnormallymeet CirrhosisoftheliverInfectionwithhepatitisBvirusorhepatitisCvirus Polycysticliverdisease Carolisyndrome InflammatoryboweldiseaseUlcerativecolitis Crohn’sdiseaseOlderage:mostpeoplediagnosedwithcholangiocarcinomaareintheir60sor70sEthnicityandgeographyTheriskishighestamongHispanicAmericansintheU.S.WorldwideitismorecommoninSoutheastAsiaandChinaObesityNon-alcoholicfattyliverdisease Exposuretothoriumdioxide(Thorotrast),aradioactivecontrastagentusedforX-raysuntilthe1950s(itisnolongerused)FamilyhistoryofbileductcancerDiabetesAlcoholco
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