1 : something that causes much distress a plague of locusts · 2 : a disease that causes death and spreads quickly to a large number of people · 3 : bubonic plague.LoginSignUpHello,Games&QuizzesThesaurusWordoftheDayFeaturesBuyingGuideM-WBooksMyWordsMyWordsViewRecentsAccountLogOutplaguenounSaveWord\ˈplāg\EssentialMeaningofplague1old-fashioned:alargenumberofharmfulorannoyingthingsThecountrywashitbyaplagueofnaturaldisastersthatyear.aplagueoflocustsTherehasbeenaplagueofbankrobberiesinthearea.2:adiseasethatcausesdeathandthatspreadsquicklytoalargenumberofpeopleaplaguethatsweptthroughthetribeinthe1600satimeofplague3:bubonicplagueanoutbreakof(the)plagueFullDefinitionofplague (Entry1of2)1a:adisastrouseviloraffliction:calamityb:adestructivelynumerousinfluxormultiplicationofanoxiousanimal:infestationaplagueoflocusts2a:anepidemicdiseasecausingahighrateofmortality:pestilenceb:avirulentcontagiousfebrilediseasethatiscausedbyabacterium(Yersiniapestis)andthatoccursinbubonic,pneumonic,andsepticemicforms—calledalsoblackdeath3a:acauseofirritation:nuisanceb:asuddenunwelcomeoutbreakaplagueofburglariesplagueverbplagued;plaguingDefinitionofplague (Entry2of2)transitiveverb1:tosmite,infest,orafflictwithorasifwithdisease,calamity,ornaturalevil2a:tocauseworryordistressto:hamper,burdenb:todisturborannoypersistentlyOtherWordsfromplagueSynonymsChoosetheRightSynonymExampleSentencesLearnMoreAboutplagueKeepscrollingformoreOtherWordsfromplagueVerbplaguernounSynonymsforplagueSynonyms:Nounpest,pestilenceSynonyms:Verbafflict,agonize,anguish,bedevil,beset,besiege,curse,excruciate,harrow,persecute,rack,torment,tortureVisittheThesaurusforMore ChoosetheRightSynonymforplagueVerbworry,annoy,harass,harry,plague,pester,teasemeantodisturborirritatebypersistentacts.worryimpliesanincessantgoadingorattackingthatdrivesonetodesperation.pursuedapolicyofworryingtheenemyannoyimpliesdisturbingone'scomposureorpeaceofmindbyintrusion,interference,orpettyattacks.you'redoingthatjusttoannoymeharassimpliespettypersecutionsorburd