Malaria is one of the most important public health problems worldwide. Globally, an estimated 3.3 billion people in 97 countries and territories ...SkiptomaincontentAdvertisementSearchallBMCarticlesSearchDownloadPDFResearchOpenAccessPublished:07September2016TheincreasingimportanceofPlasmodiumovaleandPlasmodiummalariaeinamalariaeliminationsetting:anobservationalstudyofimportedcasesinJiangsuProvince,China,2011–2014YuanyuanCao1,WeimingWang1,YaobaoLiu1,ChrisCotter2,HuayunZhou1,GuodingZhu1,JianxiaTang1,FengTang1,FengLu1,SuiXu1,YapingGu1,ChaoZhang1,JulinLi1&JunCao1,3 MalariaJournalvolume 15,Article number: 459(2016)Citethisarticle3106Accesses32Citations8AltmetricMetricsdetailsAbstractBackgroundFollowinginitiationofChina’sNationalMalariaEliminationActionPlanin2010,indigenousmalariainfectionsinJiangsuProvincedecreasedsignificantly.MeanwhileimportedPlasmodiuminfectionshaveincreasedsubstantially,particularlyPlasmodiumovaleandPlasmodiummalariae.Giventheriskformalariaresurgence,thereisanurgentneedtounderstandtheincreaseinimportedP.ovaleandP.malariaeinfectionsasChinaworkstoachievenationalmalariaelimination.MethodsAnobservationalstudyofimportedmalariacasesinJiangsuProvince,Chinawascarriedoutfortheperiodof2011–2014.ResultsAtotalof1268malariacaseswerereportedinJiangsuProvincefrom2011to2014.AlthoughimportedPlasmodiumfalciparumcases(n = 1058)accountedfor83.4 %ofallreportedcasesinJiangsu,P.ovalecases(14,19,30,and46)andtheirproportion(3.7,9.6,8.8,and13.0 %)ofallmalariacasesincreasedoverthe4 years.Similarly,P.malariaecases(seven,two,nine,and10)andproportion(1.9,1.0,2.6,and2.8 %)ofallmalariacasesincreasedslightlyduringthistime.Atotalof98casesofPlasmodiumovalecurtisi(47/98,48 %)andPlasmodiumovalewallikeri(51/98,52 %)wereidentifiedaswell.LatencyperiodsweresignificantamongthesePlasmodiuminfections(p = 0.00).Also,thisstudyfoundthatthelatencyperiodsofP.ovalesp.,P.malariaeandPlasmodiumvivaxweresignificantlylongerthanP.falciparum.However,forbothP.ovalecurtisiandP.ovalewallikeriinfections,thelat