So far, doxycycline, azithromycin, and chloramphenicol are common antibiotics for treating scrub typhus. ... Chloramphenicol and tetracycline are ...EfficacyandSafetyofAntibioticsforTreatmentofScrubTyphus:ANetworkMeta-analysis|GlobalHealth|JAMANetworkOpen|JAMANetworkOurwebsiteusescookiestoenhanceyourexperience.Bycontinuingtouseoursite,orclicking"Continue,"youareagreeingtoourCookiePolicy | Continue[SkiptoNavigation]fulltexticonFullTextcontentsiconContentsfigureiconFigures/TablesmultimediaiconMultimediaattachiconSupplementalContentreferencesiconReferencesrelatediconRelatedcommentsiconCommentsDownloadPDFCommentTopofArticleKeyPointsAbstractIntroductionMethodsResultsDiscussionConclusionsArticleInformationReferencesFigure1. PRISMAFlowDiagramViewLargeDownloadPRISMAindicatesPreferredReportingItemsforSystematicReviewsandMeta-analyses;RCT,randomizedclinicaltrial.Figure2. NetworkMeta-analysisGraphsofAntibioticsinRandomizedClinicalTrials(RCTs)andRetrospectiveStudiesViewLargeDownloadLinewidthisproportionaltothenumberofstudiescomparingeverypairoftreatments.Sizeofeverycircleisproportionaltothenumberofpatients.A,networkmeta-analysisgraphofdrugsforcomparingefficacyofRCTs.B,networkmeta-analysisgraphofdrugsforcomparingthedefervescencetimeofRCTs.C,networkmeta-analysisgraphofdrugsforcomparingsafetyofRCTs.D,networkmeta-analysisgraphofdrugsforcomparingefficacyofretrospectivestudies.E,networkmeta-analysisgraphofdrugsforcomparingthedefervescencetimeofretrospectivestudies.Figure3. NetworkMeta-analysisforAllStudiesandRankingoftheDefervescenceTimeofAntibioticsViewLargeDownloadAntibioticsvsazithromycin(referencedrug).A,comparisonsofdrugsinRCTsforefficacy.B,comparisonsofdrugsinRCTsforthedefervescencetime.C,comparisonsofdrugsinRCTsforsafety.D,comparisonsofdrugsinretrospectivestudiesforefficacy.E,comparisonsofdrugsinretrospectivestudiesforthedefervescencetime.MDindicatesmeandeviation;OR,oddsratio.Table. PairwiseComparisonsofDrugsinRCTsandRetrospectiveStudiesforDefervescenceTimeandEfficacyaViewLarg