Chemotherapy is used to treat poorly differentiated cancer of unknown primary. Learn about when chemotherapy is used and what chemotherapy drugs are ...You are here: Cancerinformation/Cancertypes/Cancerofunknownprimary/Treatment/PoorlydifferentiatedcarcinomaSelectthetextbelowandcopythelink.×RecentlyviewedpagesCancerofunknownprimary-PoorlydifferentiatedcarcinomaPoorlydifferentiatedcarcinomaCancerofunknownprimaryCanceroustumoursRisksRiskreductionstrategiesSignsandsymptomsDiagnosisPrognosisandsurvivalSurvivalstatisticsTreatmentAdenocarcinomaofunknownprimaryPoorlydifferentiatedcarcinomaSquamouscellcarcinomaofunknownprimaryNeuroendocrinecarcinomaofunknownprimaryUndifferentiatedcarcinomaChemotherapyRadiationtherapyHormonaltherapySurgeryTargetedtherapyFollow-upSupportivecareStatisticsPreviousNextA-|A|A+TreatmentsforpoorlydifferentiatedcarcinomaofunknownprimaryThefollowingaretreatmentoptionsforpoorlydifferentiatedcarcinomaofunknownprimary(CUP).Yourhealthcareteamwillsuggesttreatmentsbasedonyourneedsandworkwithyoutodevelopatreatmentplan.WhendecidingwhichtreatmentstoofferforpoorlydifferentiatedCUP,yourhealthcareteamwillconsider:whetheritisfavourable-riskorpoor-riskCUPwhereandhowmanydifferentplacescancerisfoundprognosisperformancestatuswherethecancermayhavestarted(calledtheprimarysite)youroverallhealthyourageyourpreferencesfortreatmentChemotherapyChemotherapymaybeofferedforpoorlydifferentiatedCUP.Researchersarestilllookingforthebestchemotherapycombinationsforthistypeofcancer.ExtragonadalgermcelltumoursWhenpoorlydifferentiatedCUPisfoundinadultsundertheageof40,doctorsusuallythinkthattheoriginaltumourwasanextragonadalgermcelltumour.Thistypeoftumourstartsinthegermcells.Germcellsareusuallyfoundinthetesticlesorovaries,butextragonadalgermcelltumoursstartingermcellsthatareoutsideofthetesticlesorovaries.ChemotherapyfortesticularcancermaybeofferedtoyoungermenwithapoorlydifferentiatedCUP.ChemotherapyforovariangermcelltumoursmaybeofferedtoyoungwomenwithapoorlydifferentiatedCUP.Otherpoorlyd