Pathogenesis of Lassa virus infection in guinea pigs. ... A rodent model for human Lassa fever was developed which uses inbred (strain 13) and outbred ...

Pathogenesis[edit]. Lassa fever is mostly caused by the Lassa mammarenavirus. The symptoms include flu-like illness characterized by ...

Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100000 ...

Abstract. Infection with Lassa virus in humans may take many forms. Such infections are often asymptomatic, but in those who become ill, the disease can range ...

Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 ...

... Lassa fever (LF) also called Lassa hemorrhagic fever is a disease caused by infection with a zoonotic virus called Lassa virus (LASV). LASV is ...

reported previously; Lassa virus was isolated from blood antemortem. GROSS PATHOLOGICAL FINDINGS. As in many other viral diseases, the gross patho- logy ...

The virus pathogenesis is still unclear, but it has been shown that the virus chiefly target the antigen-presenting cells (mainly dendritic cells) and endothelial cells [32]. Lassa virus infects most tissues in the human body when gained entry.

One possible mechanism involved in Lassa fever pathogenesis could be infection-triggered induction of uncontrolled cytokine expression similar to what is seen in sepsis. This hypothesis is supported by experimental data obtained from a case of fatal Lassa fever imported into Germany in 2000 [69].