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1. Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring ...BenzodiazepineFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchClassofpsychoactivedrugswithacorechemicalstructureofbenzeneanddiazepinerings"Benzo"redirectshere.Forthederivativedrugofbenzofuran,seeBenzofury.BenzodiazepinesDrugclassLorazepam,oneofthemorecommonlyprescribedbenzodiazepines.ClassidentifiersUseAnxiety,seizures,musclespasmsATCcodeN05BAModeofactionGABAAreceptorInWikidataBenzodiazepines(BZD,BDZ,BZs),sometimescalled"benzos",areaclassofpsychoactivedrugswhosecorechemicalstructureisthefusionofabenzeneringandadiazepinering.Thefirstsuchdrug,chlordiazepoxide(Librium),wasdiscoveredaccidentallybyLeoSternbachin1955,andmadeavailablein1960byHoffmann–LaRoche,which,since1963,hasalsomarketedthebenzodiazepinediazepam(Valium).[1]In1977benzodiazepinesweregloballythemostprescribedmedications.[2]Theyareinthefamilyofdrugscommonlyknownasminortranquilizers.[3]Benzodiazepinesenhancetheeffectoftheneurotransmittergamma-aminobutyricacid(GABA)attheGABAAreceptor,resultinginsedative,hypnotic(sleep-inducing),anxiolytic(anti-anxiety),anticonvulsant,andmusclerelaxantproperties.Highdosesofmanyshorter-actingbenzodiazepinesmayalsocauseanterogradeamnesiaanddissociation.[4]Thesepropertiesmakebenzodiazepinesusefulintreatinganxiety,insomnia,agitation,seizures,musclespasms,alcoholwithdrawalandasapremedicationformedicalordentalprocedures.[5]Benzodiazepinesarecategorizedaseithershort,intermediary,orlong-acting.Short-andintermediate-actingbenzodiazepinesarepreferredforthetreatmentofinsomnia;longer-actingbenzodiazepinesarerecommendedforthetreatmentofanxiety.[6]Benzodiazepinesaregenerallyviewedassafeandeffectiveforshort-termuse,whichisconsideredtwotofourweeks,[7]althoughcognitiveimpairmentandparadoxicaleffectssuchasaggressionorbehavioraldisinhibitionoccasionallyoccur.Aminorityofpeoplecanhaveparadoxicalreactionssuchasworsenedagitationorp



2. Benzodiazepines Drug Class: List, Uses, Side Effects, Types ...

What are some examples of benzodiazepines? · alprazolam (Xanax) · chlordiazepoxide (Librium) · clonazepam (Klonopin) · clorazepate (Tranxene) · diazepam ( ...BenzodiazepinesPharmacyAuthor:Annette(Gbemudu)Ogbru,PharmD,MBAMedicalEditor:JayW.Marks,MDReviewedon4/1/2021home > benzodiazepinesWhatAreBenzodiazepines?Whatarebenzodiazepines,andhowdotheywork?TypesofDrugsAretheredifferencesbetweenbenzodiazepines?SideEffectsWhatarethesideeffectsofbenzodiazepines?DrugInteractionsWithwhichdrugsdobenzodiazepinesinteract?DrugExamplesWhataresomeexamplesofbenzodiazepines?AddictionWhatarethedangersofbenzodiazepineaddiction?WithdrawalWhatarethedangersofbenzodiazepinewithdrawal?Whatarebenzodiazepines,andhowdotheywork?Benzodiazepinesareaclassofdrugsprimarilyusedfortreatinganxiety,buttheyalsoareeffectiveintreatingseveralotherconditions.Theexactmechanismofactionofbenzodiazepinesisnotknown,buttheyappeartoworkbyaffectingneurotransmittersinthebrain,chemicalsthatnervesreleaseinordertocommunicatewithothernearbynerves.Oneoftheseneurotransmittersisgamma-aminobutyricacid(GABA),aneurotransmitterthatsuppressestheactivityofnerves.Scientistsbelievethatexcessiveactivityofnervesmaybethecauseofanxietyandotherpsychologicaldisorders,andbenzodiazepinesreducetheactivityofnervesinthebrainandspinalcordbyenhancingtheeffectsofGABA.Forwhatconditionsarebenzodiazepinesused?Benzodiazepinesareusedfortreating:anxietyandpanicseizures(convulsions),andinsomniaortroublesleeping.Theyalsoareusedfor:generalanesthesia,sedationpriortosurgeryordiagnosticprocedures,musclerelaxation,alcoholwithdrawalanddrug-associatedagitation,nauseaandvomiting,depression,andpanicattacks.Aretheredifferencesbetweenbenzodiazepines?Benzodiazepinesdifferinhowquicklytheystartworking,howlongtheycontinuetowork,andforwhattheyaremostcommonlyprescribed.Diazepam(Valium)andclorazepate(Tranxene)havefastonsetsofactionandusuallystartworkingwithin30to60minutes.Oxazepam(Serax)hasaslowonset,andlorazepam(Ativan),alprazolam(Xanax),andclonazepam(Klonopin)haveintermedi



3. Benzodiazepines: Uses, types, side effects, and risks

Benzodiazepines are a group of drugs called nervous system depressants. People may take them to treat anxiety or sleeping issues. Common ...ThebenefitsandrisksofbenzodiazepinesMedicallyreviewedbyAlanCarter,Pharm.D.—WrittenbyJosephNordqvist—UpdatedonNovember8,2020UsesFunctionTypesSideeffectsInteractionsMisuseTakeawayBenzodiazepinesareaclassofdrugsthatcantreatarangeofconditions.Doctorsoftenprescribethemtotreatanxiety,seizures,andinsomnia.Theshort-termuseofthesemedicationsisusuallysafeandeffective,butlong-termusecanleadtotolerance,dependence,andotheradverseeffects.Therearedifferenttypesofbenzodiazepines,andtheyhavedifferentuses.Theyinclude:alprazolam(Xanax)clonazepam(Klonopin)diazepam(Valium)lorazepam(Ativan)midazolam(Versed)Takingtoomuchofabenzodiazepinecanbedangerous,andmixingitwithalcoholorothersubstancescanbefatal.Thisarticlelooksathowbenzodiazepineswork,theiruses,andtherelatedsideeffectsandrisks.UsesBenzodiazepinesaltertheactivityoftheneuronsthattriggerstressandanxietyreactions.TheFoodandDrugAdministration(FDA)haveapprovedthemforthetreatmentof:insomniageneralizedanxietydisordersocialanxietydisorderseizuredisorders,suchasepilepsypanicdisorderThetypeofbenzodiazepinewilldeterminethepotentialuses.Doctorsmayalsoprescribethesedrugsoff-labelforvariousotherconditionsandissues,including:othersleepdisordersticdisordersbipolardisordertomanagealcoholwithdrawalTheymayalsousetheminpreparationforsomemedicalprocedures.FunctionBenzodiazepinesworkbyenhancingtheeffectofaneurotransmitterknownasgamma-aminobutyricacid,orGABA.Neurotransmittersarechemicalsthatcommunicatemessagesbetweenbraincells.Thesemessagescanhaveeitherastimulatingoracalmingeffect.GABAisaneurotransmitterthatsendscalmingmessagestothebody.Whenapersonfeelsanxious,overstimulationoccursinthebrain.Whenpeopletakebenzodiazepines,thebrainwillsendmessagestocounterthisoverstimulation.Thisactivitycanreducethesymptomsofanxiety.TypesTherearemanydifferentbenzodiazepines.Theydifferintermsofpotency,howquicklythebodyabsorbsthem,andtheir



4. (Benzodiazepines Abuse screen ) 臺中榮總全球資訊網 ...

檢驗項目. (中文). 苯二氮平類藥物濫用篩檢. 檢驗 健保碼, 10809B. 檢驗 計價碼. 66019020. 檢驗項目. (英文). Benzodiazepines Abuse screen.跳到主要內容區塊最新消息門診抽血服務時間部科簡介部科簡介人員編制服務時間收檢單位一覽科室簡介服務項目表原始檢體收集手冊檢驗報告作業程序聯絡方式活動花絮衛教專區公開資訊儀器設備圖生化科微生物科一般檢驗科輸血醫學科細胞病理科外科病理科一般病理科分子病理科TAF證書申請常用表單問與答教育訓練教育訓練醫學倫理常用連結分享中榮首頁單位首頁English選擇分院埔里分院嘉義分院灣橋分院臺中榮民總醫院×:::快捷選單網路掛號看診進度即時動態衛教專區服務諮詢交通指南健康檢查常見問答該看哪一科:::首頁BenzodiazepinesAbusescreen引用(3)2020/12/1714:35:412016檢驗項目(中文)苯二氮平類藥物濫用篩檢檢驗健保碼10809B檢驗計價碼66019020檢驗項目(英文)BenzodiazepinesAbusescreen可自費是自費價格320元參加認證否 完成檢驗申請的說明由EHIS進行醫囑建立委託其他實驗室代檢無接受代檢是 檢體種類血液檢體容器檢體量5ml紅黃含膠管(編號:30)檢體件數之限制不適用採檢部位不適用病人準備說明無需特別準備病人自行採檢說明不適用最適採檢時間無特殊要求檢體接收與退件條件請參照實驗室規範生物參考區間≦300ng/mL實驗室檢體儲存條件2~8℃冷藏,期限為21天臨床決策值>300ng/mL實驗室檢體可加作/複驗之儲存時限加作效期7天,複驗效期7天方法學EMIT檢體運送條件與時限立刻送毒物科實驗室執行單位(地點)門診大樓後棟五樓毒物科實驗室受理時間週一至週五,正常上班時間收檢地點收檢單位一覽表諮詢聯絡方式TEL:04-23592525分機:3671報告完成時間院內:21個工作天代檢:21個工作天注意/限制事項無臨床意義/實驗室解釋BENZ屬抗焦慮藥物,常用的有十幾種之多,主要用途在緩解精神性有關的情緒症候群(例如精神亢奮、焦慮、肌肉緊張等),適應症包括抗焦慮、抗癲癇、緩解肌肉高張、治療失眠。

這類藥品由於副作用較巴比妥酸鹽為低,安全性較高,故已逐漸取代巴比妥酸鹽,成為目前最廣泛使用之安眠鎮靜劑。

這類治療用的藥物近年來也被不法之徒作為濫用藥物使用,常被濫用的有FM2(Flunitrazepam,RohypnolR)、Diazepam(ValiumR,又名安定、煩寧),及俗稱小白板之Triazolam,和俗稱蝴蝶片的Alprazolam(XanaxR)。

本類藥品長期使用會產生耐藥性、依賴性及出現嗜睡、步履不穩、注意力不集中、記憶力和判斷力減退等症狀,突然停藥亦會產生戒斷症候群。

單純只是BENZ使用過量患者,大都呈現肌肉過度鬆弛及深度睡眠狀態,較少造成死亡。

但若與酒精或其它中樞神經抑制劑併用,則危險性大為提高,許多濫用者係因精神恍惚造成意外或因吸入嘔吐物而致死。

  更新日期2020/10/12資料來源 回上一頁展開



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