Canine herpesviral infection is a severe, often fatal, disease of puppies. In adult dogs, it may be associated with upper respiratory infection, ...MSDManualPleaseconfirmthatyouareahealthcareprofessionalYesNoLeavethisSite?Thelinkyouhaveselectedwilltakeyoutoathird-partywebsite.Wedonotcontrolorhaveresponsibilityforthecontentofanythird-partysite.ContinueCancelhoneypotlinkHOMEVETERINARYCONTENTCommonVeterinaryTopicsBehaviorCirculatorySystemClinicalPathologyandProceduresDigestiveSystemEarDisordersEmergencyMedicineandCriticalCareEndocrineSystemExoticandLaboratoryAnimalsEyeDiseasesandDisordersGeneralizedConditionsImmuneSystemIntegumentarySystemManagementandNutritionMetabolicDisordersMusculoskeletalSystemNervousSystemPharmacologyPoultryPublicHealthReproductiveSystemRespiratorySystemSpecialSubjectsToxicologyUrinarySystemResourcesVideosFiguresImagesQuizzesViewAllResourcesPETHEALTH&WELLNESSUnderstandingYourPet'sHealthDogOwnersCatOwnersHorseOwnersBirdOwnersAllOtherPetsSpecialSubjectsUserGuideGlossaryRESOURCESAbbreviationsAudioCaseStudiesClinicalCalculatorsFiguresGlossaryImagesInfographicsQuizzesReferenceGuidesTablesVideosQUIZZES&CASESQuizzesMoreQuizzesCasesMoreCaseStudiesABOUTOverviewHistoryPublishingandProductionStaffEditorialBoardContributorsContentProvidersPartnersUserGuideSocialMediaFAQContactUsVETERINARYPETABCDEFGHIJKLMNOPQRSTUVWXYZABCDEFGHIJKLMNOPQRSTUVWXYZVeterinary/DogOwners/DisordersAffectingMultipleBodySystemsofDogs/.../CanineHerpesvirus/OTHERTOPICSINTHISCHAPTERDisordersAffectingMultipleBodySystemsofDogsIntroductiontoDisordersAffectingMultipleBodySystemsofDogsCongenitalandInheritedDisordersAffectingMultipleBodySystemsofDogsActinobacillosisinDogsActinomycosisinDogsAmyloidosisinDogsAnthraxinDogsBotulisminDogsCanineDistemper(HardpadDisease)CanineHerpesvirusEhrlichiosisandRelatedInfectionsinDogsEnterotoxemiainDogsFungalInfectionsinDogsGlanders(Farcy)inDogsInfectiousCanineHepatitisLeishmaniosis(VisceralLeishmaniasis)inDogsLeptospirosisinDogsLymeDisease(LymeBorreliosis)inDog

Canine herpes virus (CHV), also known as “fading puppy syndrome,” is a viral infection that affects the reproductive organs of adult dogs. Canineherpesvirus(CHV),alsoknownas“fadingpuppysyndrome,”isaviralinfectionthataffectsthereproductiveorgansofadultdogs.WhileadultdogsinfectedwithCHVusuallydonotshowanysymptoms,theinfectionistheleadingcauseofdeathinnewbornpuppies.Onepuppyinalittermaybeaffected,anddeathmayoccurabruptly,withlittleornowarning,oranentirelittermayperishwithina24-hourperiod.Ifthediseaseiscontractedwhenthepuppiesareolderthanthreeweeks,itisoftenlesssevere.Olderpuppieshaveamuchbetterchanceofsurvival,butmayhavelong-termeffectsofapersistentCHVinfection. HowIsCanineHerpesTransmitted?Canineherpesviruslivesinthereproductiveandrespiratorytractsofmaleandfemaledogs.Inadults,thediseaseistransmittedviaaerosolanddirectcontact,includingsneezing,coughing,nosing,sniffing,lickingandsexualactivitiesbetweenaninfectedandanuninfecteddog.Puppiesusuallycontractthediseaseinthebirthcanalorfromnasalandoralsecretionsofthemothershortlyafterbirth.Puppiescanalsospreadthevirustooneanother. JustbecauseonepuppyinalitterisinfectedwithCHVdoesnotmeantheyallare.WhatAretheSymptomsofCanineHerpesinAdultDogs?Oftentherearen'tanysymptomsOccasionallyraisedgenitalsoresmaybeseenAbortionStillbirthKennelcoughWhatAretheSymptomsofCanineHerpesinPuppies?SuddendeathofnewbornpuppyWeakness,lethargy,cryingLackofsucklereflex/appetitePainfulabdomen,bruisingoftheabdomenSoft,yellow/greenfecesRespiratorydifficulty,nasaldischargeHemorrhages,suchasnosebleedsandsmallbruisesOlderpuppiesmaydevelopnervoussystemabnormalities,includingblindnessandseizuresCanICatchHerpesfromMyDog?No.Humansarenotatriskforcatchingcanineherpes.HowIsCanineHerpesDiagnosed?Ifapuppyisstillbornordiessoonafterbirth,anecropsyshouldbeperformedtodeterminethecauseofdeath.Therearemanypotentialcausesforpuppydeath,andyouwillwanttoevaluatewhethertherestofthelitterisatriskandwhatcareisneeded.Pleasecallyourveterinarianforinstructionsonhowtoarrangethis. Adultdo

Canine herpesvirus is best known as a severe viral infection of puppies worldwide, which often has a 100% mortality rate in affected litters.MSDManualPleaseconfirmthatyouareahealthcareprofessionalYesNoLeavethisSite?Thelinkyouhaveselectedwilltakeyoutoathird-partywebsite.Wedonotcontrolorhaveresponsibilityforthecontentofanythird-partysite.ContinueCancelhoneypotlinkHOMEVETERINARYCONTENTCommonVeterinaryTopicsBehaviorCirculatorySystemClinicalPathologyandProceduresDigestiveSystemEarDisordersEmergencyMedicineandCriticalCareEndocrineSystemExoticandLaboratoryAnimalsEyeDiseasesandDisordersGeneralizedConditionsImmuneSystemIntegumentarySystemManagementandNutritionMetabolicDisordersMusculoskeletalSystemNervousSystemPharmacologyPoultryPublicHealthReproductiveSystemRespiratorySystemSpecialSubjectsToxicologyUrinarySystemResourcesVideosFiguresImagesQuizzesViewAllResourcesPETHEALTH&WELLNESSUnderstandingYourPet'sHealthDogOwnersCatOwnersHorseOwnersBirdOwnersAllOtherPetsSpecialSubjectsUserGuideGlossaryRESOURCESAbbreviationsAudioCaseStudiesClinicalCalculatorsFiguresGlossaryImagesInfographicsQuizzesReferenceGuidesTablesVideosQUIZZES&CASESQuizzesMoreQuizzesCasesMoreCaseStudiesABOUTOverviewHistoryPublishingandProductionStaffEditorialBoardContributorsContentProvidersPartnersUserGuideSocialMediaFAQContactUsVETERINARYPETABCDEFGHIJKLMNOPQRSTUVWXYZABCDEFGHIJKLMNOPQRSTUVWXYZVeterinary/GeneralizedConditions/CanineHerpesviralInfection/.../OverviewofCanineHerpesviralInfection/INTHISTOPICEtiologyandPathogenesis:ClinicalFindings:Lesions:Diagnosis:Treatment:Prevention:ADDITIONALCONTENTTestyourknowledgeAnthraxAnthraxisazoonoticdiseaseaffectingabroadrangeofspecies.Naturallyoccurringinfectionscancauseillnessesthatrangefromanacute,highlyfatalformtoalessacuteandlessseriousclinicalillnessthatcanalsobefatal.Whichofthefollowingspeciesismostlikelytodevelopacutefataldiseasewithanthraxinfection? Cattle  Dogs  Humans  Pigs MoreContentVideosSOCIALMEDIAOverviewofCanineHerpesviralInfectionByKateE.Creevy,DVM,MS,DACVIM,

Canine herpesvirus 1 (CHV-1), a member of the alphaherpesvirus sub-family, is known to cause fatal infections in litters of puppies and may also be involved ...Clipboard,SearchHistory,andseveralotheradvancedfeaturesaretemporarilyunavailable.SkiptomainpagecontentCOVID-19InformationPublichealthinformation(CDC)Researchinformation(NIH)SARS-CoV-2data(NCBI)Preventionandtreatmentinformation(HHS)Español AccesskeysNCBIHomepageMyNCBIHomepageMainContentMainNavigationSearch:SearchAdvancedClipboardUserGuideSaveEmailSendtoClipboardMyBibliographyCollectionsCitationmanagerDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSavecitationtofileFormat:Summary(text)PubMedPMIDAbstract(text)CSVCreatefileCancelEmailcitationSubject:1selecteditem:9008334-PubMedTo:Format:SummarySummary(text)AbstractAbstract(text)MeSHandotherdataSendemailCancelAddtoCollectionsCreateanewcollectionAddtoanexistingcollectionNameyourcollection:Namemustbelessthan100charactersChooseacollection:UnabletoloadyourcollectionduetoanerrorPleasetryagainAddCancelAddtoMyBibliographyMyBibliographyUnabletoloadyourdelegatesduetoanerrorPleasetryagainAddCancelYoursavedsearchNameofsavedsearch:Searchterms:TestsearchtermsWouldyoulikeemailupdatesofnewsearchresults?SavedSearchAlertRadioButtonsYesNoEmail:(change)Frequency:MonthlyWeeklyDailyWhichday?ThefirstSundayThefirstMondayThefirstTuesdayThefirstWednesdayThefirstThursdayThefirstFridayThefirstSaturdayThefirstdayThefirstweekdayWhichday?SundayMondayTuesdayWednesdayThursdayFridaySaturdayReportformat:SummarySummary(text)AbstractAbstract(text)PubMedSendatmost:1item5items10items20items50items100items200itemsSendevenwhentherearen'tanynewresultsOptionaltextinemail:SaveCancelCreateafileforexternalcitationmanagementsoftwareCreatefileCancelYourRSSFeedNameofRSSFeed:Numberofitemsdisplayed:510152050100CreateRSSCancelRSSLinkCopyFulltextlinksElsevierScienceFulltextlinksActionsCiteFavoritesDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSharePermalinkCopyPagenavigationTitle&authorsAbstractSimilarar

Canine herpes virus, more commonly known as fading puppy syndrome, can be a devastating disease if it hits your kennel.EventSearchFindaPuppyRegisterYourDogShopAKCTVSignInBreedsA-ZExpertAdviceProducts&ServicesSports&EventsClubs&DelegatesBreedExplorerViewAllBreedsFindByBreedNameSelectABreedAffenpinscherAfghanHoundAiredaleTerrierAkitaAlaskanKleeKaiAlaskanMalamuteAmericanBulldogAmericanEnglishCoonhoundAmericanEskimoDogAmericanFoxhoundAmericanHairlessTerrierAmericanLeopardHoundAmericanStaffordshireTerrierAmericanWaterSpanielAnatolianShepherdDogAppenzellerSennenhundAustralianCattleDogAustralianKelpieAustralianShepherdAustralianStumpyTailCattleDogAustralianTerrierAzawakhBarbadodaTerceiraBarbetBasenjiBassetFauvedeBretagneBassetHoundBavarianMountainScentHoundBeagleBeardedCollieBeauceronBedlingtonTerrierBelgianLaekenoisBelgianMalinoisBelgianSheepdogBelgianTervurenBergamascoSheepdogBergerPicardBerneseMountainDogBichonFriseBiewerTerrierBlackandTanCoonhoundBlackRussianTerrierBloodhoundBluetickCoonhoundBoerboelBohemianShepherdBologneseBorderCollieBorderTerrierBorzoiBostonTerrierBouvierdesFlandresBoxerBoykinSpanielBraccoItalianoBraqueduBourbonnaisBraqueFrancaisPyreneanBriardBrittanyBroholmerBrusselsGriffonBullTerrierBulldogBullmastiffCairnTerrierCanaanDogCaneCorsoCardiganWelshCorgiCarolinaDogCatahoulaLeopardDogCaucasianShepherdDogCavalierKingCharlesSpanielCentralAsianShepherdDogCeskyTerrierChesapeakeBayRetrieverChihuahuaChineseCrestedChineseShar-PeiChinookChowChowCirnecodell’EtnaClumberSpanielCockerSpanielCollieCotondeTulearCroatianSheepdogCurly-CoatedRetrieverCzechoslovakianVlcakDachshundDalmatianDandieDinmontTerrierDanish-SwedishFarmdogDeutscherWachtelhundDobermanPinscherDogoArgentinoDoguedeBordeauxDrentschePatrijshondDreverDutchShepherdEnglishCockerSpanielEnglishFoxhoundEnglishSetterEnglishSpringerSpanielEnglishToySpanielEntlebucherMountainDogEstrelaMountainDogEurasierFieldSpanielFinnishLapphundFinnishSpitzFlat-CoatedRetrieverFrenchBulldogFrenchSpanielGermanLonghairedPointerGer

Canine herpes virus (CHV) is a serious and often fatal viral disease in puppies. In adult dogs, it can cause eye disease, ...HealthyDogsNewsReferenceSlideshowsQuizzesVideosQuestions&AnswersDiet&NutritionBehavior&TrainingPuppyCarePreventiveCareCommonConditionsExpertQ&AsShortcutsDogHealthToolDogConditionsA-ZDogSymptomsA-ZDogBehaviorA-ZMoreDogTopicsHealthyPetsHealthyDogsReferenceInthisArticleInthisArticleInthisArticleHowCanineHerpesVirusIsTransmittedSymptomsofCanineHerpesinAdultDogsSymptomsofDogHerpesinPuppiesHowCommonIsDogHerpes?DiagnosisofCanineHerpesVirusTreatmentforCanineHerpesVirusPreventingCanineHerpesVirusCanineherpesvirus(CHV)isaseriousandoftenfatalviraldiseaseinpuppies.Inadultdogs,itcancauseeyedisease,anupperrespiratoryinfection,andinflammationinthevaginaorforeskinofthepenis. Inadultdogs,canineherpesisconsideredareproductivehealthproblemratherthanalungproblem,asitisinpuppies.Pregnantdogsthatdevelopcanineherpesinthelastfewweeksofapregnancycanexperiencestillbirth.Theycanalsopassherpestothelitterbeforeorduringbirth.Dogherpesisseriousforpuppiesandcanresultindeathandlitterloss.HowCanineHerpesVirusIsTransmittedYourdogcangetcanineherpesvirusfromdirectcontactwiththenose,mouth,orvaginalfluidsfromadogthathasthevirus.Sexualcontactbetweendogscancausetransmission.Itcanalsotransferthroughnormallicking,sniffing,andnosing.Canineherpesinpuppiesisalsotransmittedthroughdirectcontactwithfluids.Puppiesborntoaninfectedmothercangetthediseasewhileinthewomborafterbirthfromthemother’svaginal,nose,ormouthfluids.Theviruscanaffectthewholelitterorjustonepuppy. SymptomsofCanineHerpesinAdultDogsMostadultdogsdonothaveanysymptomsormayhaveonlymildsymptomsfromherpes.Itisoftennotasseriousinadultdogs. Symptomsinclude:EyedischargeEyeinflammationCoughingSneezingNasaldischargeInflamedpenisforeskinGenitalsoresVaginaldischargeAbortionStillbirthSymptomsofDogHerpesinPuppiesCanineherpesinpuppiesusuallydevelopsintwodifferentways. Ifthepuppiesareinfectedaftertheageofthreeweeks,herpescandevelopintoalunginfec

Canine herpesvirus (CHV) is in the order Herpesvirales, family Herpesviridae, subfamily Alphaherpesvirinae, genus Varicellovirus as the species Canid ...Inthissection:Inthissection:TestDataPrintThisPageCVMAnimalHealthDiagnosticCenterLaboratoriesVirologyTestDataCanineHerpesvirusAntibodyNeutralizationCanineherpesvirus(CHV)isintheorderHerpesvirales,familyHerpesviridae,subfamilyAlphaherpesvirinae,genusVaricellovirusasthespeciesCanidalphaherpesvirus1.Asatypicalalphaherpesvirus,itsharesmanyofthepropertiescommontothisgroupofviruses.Assuch,mostinfectionsaresubclinicalandthevirusestablisheslatencyinthehostforthelifeoftheanimal.Viruswillrecrudesceforunknownreasonsatunpredictableintervalsinmanyinstanceswithnoovertsigns.Itisthroughthismechanismthatthevirusspreadsandpersistsinthecaninepopulation.ThemostsignificantclinicalfindingslinkedtoCHVinfectionsarerespiratorysigns,ocularlesionsandneonatalmortalitywhichisbyfartheissueofmostconcern.Neonatalmortalitiesmostfrequentlyoccurwithinthefirsttwoweeksoflife.Theetiologyofthissyndromeistheinfectionofasero-negativepregnantdoglateingestationsothatthereisinfectiousvirusintheenvironmentandwithtoolittletimeforantibodiestobepresentinthecolostrumtoprovidepassiveprotectiontothepuppies.The"goldenrule"statesthatadogshouldloseonlyonelitterofpuppiestoCHVassubsequentlitterswillbeprotectedfromtheclinicaldiseasebytheneutralizingantibodiesinthecolostrum.Forownersthatareconcernedabouttheneonatalpuppyinfections,itisveryhelpfultoknowtheserologicalstatusoftheanimalsthatmightbebred.Antibodypositiveanimalsareofnoconcernbutantibodynegativeanimalsshouldbemanagedtoavoidexposuresduringthepregnancy.AstherearenolicensedvaccinesforCHVintheUS,allantibodypositiveanimalsshouldbeconsideredlatentlyinfectedandcapableofspreadingthevirus.ThechartbelowrepresentsthepositiveCHVneutralizingantibodyreports(306)issuedbytheAHDCfromatotalof714testrequestsorasero-prevalenceof42.9%.Asthesearenotrandomsamplesstratifiedbyageorgeographicregion,thecaninepopulationsero-prevalencemaybediff

Canine herpesvirus or canine herpes is a systemic, often fatal disease of puppies caused by canine herpes virus. It may remain latent in tissues after a dog ...Wearecommittedtocaringforyourpet–whilemaintainingthehighestlevelofsafetyforourAssociatesandpetowners.Wethankyouforyourcontinuedpatienceandsupport. Learnmore aboutourCOVID-19responseandguidelines.ReadMoreWhatiscanineherpesvirus?Canineherpesvirusorcanineherpesisasystemic,oftenfataldiseaseofpuppiescausedbycanineherpesvirus(CHV).CHVisseenmostcommonlyinAsiaandEuropeindogs,coyotes,andwolves.CHVdoesnotcauseinfectioninhumans.Itmayremainlatentorhiddenandquietintissuesafteradogisinfectedandmaybepassedontootherdogs,particularlytofetusesdevelopinginthemother'suterus.Stressorotherillnessmaycauserecurrenceofillnessinadogthathaspreviouslybeeninfected.Theincubationperiodinpuppiesisfourtosixdays,afterwhichclinicalsignsdeveloporsuddendeathoccurs.Whataretheclinicalsignsofcanineherpesvirusinfection?Themostcommonclinicalsignsoccurinpuppiesunderfourweeksofage.Littermortality(death)ratesarehighinCHV.Inpuppies,clinicalsignsincludedifficultybreathing,athicknasaldischarge,lossofappetite(anorexia),grayishyelloworgreensoft,odorlessstools,persistentcrying,seizures,andsuddendeath.Puppiesthatappeartobemildlyaffectedoftenlaterdevelopneurologicalsignsorblindness."Littermortality(death)ratesarehighinCHV."Mostadultdogshaveclinicalsignsthatarenonspecific,including:coughingandsneezingcausedbyupperrespiratoryinfection,miscarriage,andlesionsontheexternalgenitalia.Infectionsaffectingtheeyescancausesquinting,recurrentocular(eye)discharge,conjunctivitis,andcornealulcers.HowdoesadogbecomeinfectedwithCHV?Youngfemalesandtheirpuppiesareatgreatestrisk.Directcontactbetweeninfectedandnon-infecteddogscausestransmissionofthevirus.Sincethevirusiswidespread,theriskofinfectionisrelativelygreat.ClosedbreedingkennelsthatexperienceasuddenincreaseinmiscarriagesshouldbetestedforCHV.Howiscanineherpesvirusdiagnosed?Diagnosisisusuallybasedonclinicalsignsinaffecteddogs.T