Abstract. Bartonella henselae, the causative agent of cat scratch disease, establishes long-term bacteremia in cats, in which it attaches to and invades feline ...NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutJournalListInfectImmunv.66(7);1998JulPMC108372InfectImmun.1998Jul;66(7):3462–3466.PMCID:PMC108372PMID:9632625NoteBartonellahenselaeInvasionofFelineErythrocytesInVitroJaneR.Mehock,1CraigE.Greene,2FrankC.Gherardini,1Tae-WookHahn,1andDuncanC.Krause1,*JaneR.MehockDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602FindarticlesbyJaneR.MehockCraigE.GreeneDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602FindarticlesbyCraigE.GreeneFrankC.GherardiniDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602FindarticlesbyFrankC.GherardiniTae-WookHahnDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602FindarticlesbyTae-WookHahnDuncanC.KrauseDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602FindarticlesbyDuncanC.KrauseAuthorinformationArticlenotesCopyrightandLicenseinformationDisclaimerDepartmentsofMicrobiology1andSmallAnimalMedicine,2UniversityofGeorgia,Athens,Georgia30602*Correspondingauthor.Mailingaddress:DepartmentofMicrobiology,523BiologicalSciencesBuilding,UniversityofGeorgia,Athens,GA30602.Phone:(706)542-2671.Fax:(706)542-2674.E-mail:[email protected]:R.N.MooreReceived1997Dec22;Revisionsrequested1998Feb3;Accepted1998Mar31.Copyright©1998,AmericanSocietyforMicrobiologyThisarticlehasbeencitedbyotherarticlesinPMC.Bartonellahenselae,thecausativeagentofcatscratchdisease,establisheslong-termbacteremiaincats,inwhichitattachestoandinvadesfelineerythrocytes(RBC).FelineRBCinvasionwasassessedinvitro,basedongentamicinselectionforintracellularbacteriaorbylaserconfocalmicroscopyanddigitalsectioning.Invasionratesrangedfrom2to20%oftheinoculum,

The cat (Felis catus) is the primary but not sole reservoir for B. henselae [18], the causal agent of human cat scratch disease (CSD). Domestic cats ...SkiptomaincontentAdvertisementSearchallBMCarticlesSearchDownloadPDFReviewOpenAccessPublished:04December2018BartonellainfectionsincatsanddogsincludingzoonoticaspectsAlejandraÁlvarez-Fernández1,EdwardB.Breitschwerdt2&LaiaSolano-Gallego ORCID:orcid.org/0000-0001-8479-48961 Parasites&Vectorsvolume 11,Article number: 624(2018)Citethisarticle9193Accesses24Citations12AltmetricMetricsdetailsAbstractBartonellosisisavector-bornezoonoticdiseasewithworldwidedistributionthatcaninfecthumansandalargenumberofmammalsincludingsmallcompanionanimals(catsanddogs).Inrecentyears,anincreasingnumberofstudiesfromaroundtheworldhavereportedBartonellainfections,althoughpublicationshavepredominantlyfocusedontheNorthAmericanperspective.Currently,clinico-pathologicaldatafromEuropearemorelimited,suggestingthatbartonellosismaybeaninfrequentorunderdiagnosedinfectiousdiseaseincatsanddogs.ResearchisneededtoconfirmorexcludeBartonellainfectionasacauseofaspectrumoffelineandcaninediseases.Bartonellaspp.cancauseacuteorchronicinfectionsincats,dogsandhumans.Onacomparativemedicalbasis,differentclinicalmanifestations,suchasperiodsofintermittentfever,granulomatousinflammationinvolvingtheheart,liver,lymphnodesandothertissues,endocarditis,bacillaryangiomatosis,peliosishepatis,uveitisandvasoproliferativetumorshavebeenreportedincats,dogsandhumans.ThepurposeofthisreviewistoprovideanupdateandEuropeanperspectiveonBartonellainfectionsincatsanddogs,includingclinical,diagnostic,epidemiological,pathological,treatmentandzoonoticaspects.BackgroundBartonellaisagenusofAlphaproteobacteriawithinthefamilyBartonellaceae.Bartonellaspp.aresmall,thin,shortandslightlycurved,gram-negative,hemotropicandrod-shapedbacteria[1].Theyarecatalase,oxidase,ureaseandnitratereductasenegative[1].Bartonellaspp.arefastidious,slowgrowingandfacultativeintracellularpathogensthatarehighlyadaptedtoabroadsp

Abstract. The isolation of Bartonella henselae, the agent of cat scratch disease, from the blood of naturally infected domestic cats and the demonstration that cats​ ...Clipboard,SearchHistory,andseveralotheradvancedfeaturesaretemporarilyunavailable.SkiptomainpagecontentCOVID-19InformationPublichealthinformation(CDC)Researchinformation(NIH)SARS-CoV-2data(NCBI)Preventionandtreatmentinformation(HHS)Español AccesskeysNCBIHomepageMyNCBIHomepageMainContentMainNavigationSearch:SearchAdvancedClipboardUserGuideSaveEmailSendtoClipboardMyBibliographyCollectionsCitationmanagerDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSavecitationtofileFormat:Summary(text)PubMedPMIDAbstract(text)CSVCreatefileCancelEmailcitationSubject:1selecteditem:7494043-PubMedTo:Format:SummarySummary(text)AbstractAbstract(text)MeSHandotherdataSendemailCancelAddtoCollectionsCreateanewcollectionAddtoanexistingcollectionNameyourcollection:Namemustbelessthan100charactersChooseacollection:UnabletoloadyourcollectionduetoanerrorPleasetryagainAddCancelAddtoMyBibliographyMyBibliographyUnabletoloadyourdelegatesduetoanerrorPleasetryagainAddCancelYoursavedsearchNameofsavedsearch:Searchterms:TestsearchtermsWouldyoulikeemailupdatesofnewsearchresults?SavedSearchAlertRadioButtonsYesNoEmail:(change)Frequency:MonthlyWeeklyDailyWhichday?ThefirstSundayThefirstMondayThefirstTuesdayThefirstWednesdayThefirstThursdayThefirstFridayThefirstSaturdayThefirstdayThefirstweekdayWhichday?SundayMondayTuesdayWednesdayThursdayFridaySaturdayReportformat:SummarySummary(text)AbstractAbstract(text)PubMedSendatmost:1item5items10items20items50items100items200itemsSendevenwhentherearen'tanynewresultsOptionaltextinemail:SaveCancelCreateafileforexternalcitationmanagementsoftwareCreatefileCancelYourRSSFeedNameofRSSFeed:Numberofitemsdisplayed:510152050100CreateRSSCancelRSSLinkCopyFulltextlinksAtyponFreePMCarticleFulltextlinksActionsCiteFavoritesDisplayoptionsDisplayoptionsFormatAbstractPubMedPMIDSharePermalinkCopyPagenavigationTitle&authorsAbs

Cat scratch disease (CSD) is the most known disease caused by Bartonella species. The etiologic agent of CSD is B. henselae causing several syndromes in​ ...MAIN:InfectiousDisease/General:Haemoplasmosis&BartonellosisWelcome,VINPublic!LogoutWelcomeVIN LogoutChangeYourPasswordCLOSEAttendthenextWSAVACongressSearchthisResourceViewmainpageTableofContentsBrowsebySpeakerBrowsebyCategoryLoading...AnaesthesiaInhalationAnaesthesiaCRI&TIVAInhalationAgentsRespiratoryFunctionMonitoringSedation&CardiacDiseaseUpdateonCPRBehaviourDecreasingStress&AnxietyDogAggressionIntegratingBehaviourNormalBehaviourMakingSenseofMedications1MakingSenseofMedications2Stress&AnxietyCanineEndocrinologyDiabetes&QualityofLifeDiagnoseHypothyroidismInsulinResistanceTrilostaneCardiologyCardiopulmonaryBypassTechniqueCardiovascularPhysicalExaminationFelineHypertrophicCardiomyopathyCongestiveHeartFailureMitralValvePlastyCoughing&DyspneicPatientEchocardiography&DopplerImagingClinicalPathologyAnaemia:HaematologyResultsBoneMarrowSamplesDiagnosisofCoagulopathiesFineNeedleAspiratesRespiratoryCytologyPitfallsofPCRDiagnosisLiverEnzymesVitaminB12CriticalCareAcuteRespiratoryDistressSyndromeColloidsvs.CrystalloidsEmergencyCardiovascularMedicineCorticosteroidTherapyFluidCocktailsFluidResponsivenessMetabolicChangesVentilatingCriticalPatientsDentistryBeakRepairDentalFractureFelineMaxillofacialTraumaDogmainDentistryEquippingDentalOperatoryExodonticsFelineChronicGingivostomatitisLocal&RegionalAnaesthesiaRabbit&RodentDentalAbscessesNeoplasiaofTongueNon-InvasiveFractureRepairOralMasses,BumpsinCatsOralSquamousCellCarcinomaPeriodontitis&PeriodontalDebridementOronasalRepairTechniquesRodent&UnusualECMDentistryToothResorptionDermatologyAllergicDermatitisClawDiseasesAtopicDermatitisDiagnosisFleaTreatmentsFoodAllergicSkinDiseaseManagementofDemodicosisMethicillin-ResistantStaphylococciTreatingtheItchAtopicDermatitisEmergenciesBrainInjuryPatientHouseholdToxinsIntraosseousFluidDevicesOncologicalEmergenciesPainManagement:IllorInjuredRec

Cats may also harbor Bartonella clarridgeiae and (rarely) other Bartonella species. Cats become infected with Bartonella henselae from the bites of infected fleas ...SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkBartonellaInfection(CatScratchDisease,TrenchFever,andCarrión’sDisease)SectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateForVeterinariansMinusRelatedPagesDomesticpetsaresusceptibletoinfectionwithvariousspeciesofBartonellaandcanplayaroleinhumaninfection.Bartonellahenselaebacteremiahasbeendocumentedin30-40%ofdomesticandadoptedsheltercats.Kittensshowingevidenceofinfectionweremorelikelytohaveahighbacterialloadcomparedtoyoungadultcats.RatesofseropositivityforBartonellahenselaevarybyregion,with6%ofcatsshowingevidenceofexposureinIllinoiscomparedto33%inFlorida.CatsmayalsoharborBartonellaclarridgeiaeand(rarely)otherBartonellaspecies. Cats becomeinfectedwith Bartonellahenselaefromthebitesofinfectedfleasorcontactwithinfectedblood;catsinvolvedincatfightsorwhohavereceivedbloodtransfusionsaremoreatriskforinfection.DogsmaycarryBartonellavinsoniisubsp.berkhoffii,Bartonellahenselae,andotherBartonellaspecies. Bartonellainfectionismorelikelytocauseclinicalsymptomsindogscomparedtocats.LowseroprevalenceinworldwidedogpopulationssuggeststhatdogsareprobablynotanaturalreservoirforB.vinsoniiberkhoffii.Itisnotyetknownwhetherdogscantransmitinfectiontohumans.Inadditiontodogsandcats,numerousdomesticandwildanimals,includingbovine,canine,human,androdentspeciescanserveasreservoirhostsforvariousBartonellaspecies.ClinicalPresentationCatsNaturallyinfectedcatsareprimarilyasymptomatic,subclinicalcarriersofBartonellahenselae.B.henselaeinfectionsincats,alsoknownasfelinebartonellosis,mayoccasionallycauseaself-limiting,transient,febrileillnessthatlastsforapproximately48-72hours.Clinicalsymptomsofmoreseriousinfection,althoughrare,includefever,vomiting,lethargy,redeyes,swollenlymphnodes,and/ordecreasedappetite.Bacteremiacanpersistformonthswithclinicalsignsappearingwhenthe

Cats are a primary reservoir and vector for transmission of B henselae and possibly (but uncommonly) B clarridgeiae to people. One publication noted that ...

Bartonella henselae is the causative agent of cat scratch disease (CSD) in humans, a self-limiting regional lymphadenopathy and cats are its main reservoir host ...Home » FelinebartonellosisFelinebartonellosis EditedJuly,2020 TheBartonellaspeciesinfectionincatsguidelineswerefirstpublishedintheJFelineMedSurg2013,15:563-569 byMariaGraziaPennisietal.andupdatedbyFulvioMarsilioin2015andbyMariaGraziaPennisiandFulvioMarsilioin2018.ThepresentguidelineswereupdatedbyMariaGraziaPennisiandFulvioMarsilio. Synopsis ThepathogenicroleofmanyBartonellaspp.aspathogensofhumansanddomesticanimalsisstillunknown.Bartonellahenselaeisthecausativeagentofcatscratchdisease(CSD)inhumans,aself-limitingregionallymphadenopathyandcatsareitsmainreservoirhost.TheimportantroleoffleasinthetransmissionofB.henselaeandB.clarridgeiaeamongcatshasbeendemonstratedandcontactinfectionsdonotoccur. Antibodiesarenotprotectiveandantibody-positivecatsmaybereinfected.MostcatsnaturallyinfectedbyB.henselaedonotshowclinicalsignsbutsomeindividualsmaydeveloplife-threateningcardiovasculardiseases.Moreover,otherBartonellaspecies,forwhichcatsareaccidentalhosts,mayhavepathogenicproperties.BartonellosisisdiagnosedinsymptomaticBartonellapositivecatsonthebasisofexclusionofothercompatiblediagnoses,andbyassessingtheresponsetoantibiotictherapy.Nobenefitderivesfromtestinghealthycatsandhumans,exceptincasesofimmunosuppressedpeopleinthehome. Strictfleaandtickcontrolistheonlyeffectivepreventivemeasure. Bacterialproperties Bartonella(B.) aresmall(2by0.5μm),vector-transmittedGram-negativeintracellularbacteriathatarewelladaptedtooneormoremammalianreservoirhosts.Untilnow,over22Bartonellaspecieshavebeendescribed,buttheirroleaspathogensofhumansanddomesticanimalsisthesubjectofongoinginvestigations(Table1). Bartonellaspp.PrimaryreservoirVectorAccidentalhostB.bacilliformisHumansLutzomiaverrucarumNoneB.quintanaHumansPediculushumanusCat,dog,monkeyB.elizabethaeRattusnorvegicusXenopsyllacheopisHumans,dogB.grahamiiSeveralspeciesofwildmiceRodentfleasHu