ExpandallsectionsRegister/LoginTrustedmedicalexpertiseinseconds.Access1,000+clinicalandpreclinicalarticles.Findanswersfastwiththehigh-poweredsearchfeatureandclinicaltools.Tryfreefor5daysEvidence-basedcontent,createdandpeer-reviewedbyphysicians.Readthedisclaimer.ChlamydiainfectionsLastupdated:February9,2021SummaryChlamydiaceaeisafamilyofgram-negative,obligateintracellularbacteriathatincludes3organismspathogenictohumans:Chlamydiatrachomatis,Chlamydophilapneumoniae,andChlamydophilapsittaci.C.trachomatiscanbedifferentiatedintoserotypesA–C,D–K,andL1–L3.SerotypesA–Cmainlyaffecttheeyesandcausetrachoma.AninfectionwithserotypesD–Kcanresultingenitourinaryinfections(e.g.,vaginitis,PID,urethritis),conjunctivitis,andinfantpneumonia.SerotypesL1–L3,inturn,leadtosexuallytransmittedlymphogranulomavenereum.WhilebothC.pneumoniaeandC.psittaciprimarilyaffecttherespiratorysystem,C.psittacialsocausespsittacosis.Chlamydialinfectionsaremostlydiagnosedbasedonclinicalpresentationandaretreatedwithdoxycyclineormacrolides.Inallcasesofsexuallytransmittedchlamydialinfection,expeditedpartnertherapyshouldalsobeinitiatedassoonaspossible.Allocularmanifestationsarediscussedinmoredetailinthe“Conjunctivitis”article.GeneralGeneralcharacteristicsGram-negativeorganisms,thatGramstainpoorlyObligateintracellularbacteria(unabletoproduceitsownATP)Absentpeptidoglycan(muramicacid)inthecellwall,whichmakesbeta-lactamantibioticsineffectiveVisibleascytoplasmicinclusionbodiesonGiemsastainorfluorescentantibody-stainedsmearVerydifficultcultivationLifecycleFirstphase:elementarybodies(smallanddensebodiesthatcharacterizetheinfectiousstageofChlamydiaceae;stableintheextracellularenvironmentandalmostinactivemetabolically)[1]Attachmentofextracellularelementarybodiestotargetcells(mostlyontherespiratoryorurogenitalepithelium)EndocytosisTransformationintoreticulatebodiesintheendosomeSecondphase:reticulatebodies(representtheobligateintracellular,replicative,andmetabolicallyactiveformofChlamydiaceae)Replicationbyfissionandaggregatio

What Is the Treatment for Chlamydia Pneumoniae? ... Chlamydia pneumoniae infections may be cured with antibiotics, however people often recover on ...homeinfectionscenterTopicGuideCanChlamydiaPneumoniaeBeCured?MedicalAuthor:JohnP.Cunha,DO,FACOEPReviewedon8/26/2020DefinitionWhatIsChlamydiaPneumoniae?SymptomsWhatAreSymptomsofChlamydiaPneumoniae?CausesWhatCausesChlamydiaPneumoniae?DiagnosisHowIsChlamydiaPneumoniaeDiagnosed?TreatmentWhatIstheTreatmentforChlamydiaPneumoniae?ComplicationsWhatAreComplicationsofChlamydiaPneumoniae?PreventionHowDoYouPreventChlamydiaPneumoniae?GuideCanChlamydiaPneumoniaeBeCured?TopicGuideWhatIsChlamydiaPneumoniae?Chlamydiapneumoniaeisbacteriathatcandamagetheliningoftherespiratorytractincludingthethroat,lungs,andwindpipe,causingrespiratorytractinfectionssuchaspneumoniaorbronchitis. C.pneumoniaeisacommoncauseofcommunity-acquiredpneumoniaorlunginfectionsdevelopedoutsideofahospital. ChlamydiapneumoniaeisnotthesamebacteriumasChlamydiatrachomatis,whichisresponsibleforthesexuallytransmittedinfection(STI)chlamydia.WhatAreSymptomsofChlamydiaPneumoniae?Chlamydiapneumoniaegenerallycausesmildillnessandinsomecasesnosymptomsatall.Itusuallytakesabout3to4weeksforsymptomstoappearafterexposuretothebacteria. CommonsymptomsofupperrespiratorytractinfectionscausedbyChlamydiapneumoniaeinclude:SorethroatEarorsinusinfectionRunnyorstuffynoseFatigue(feelingtired)FeverHoarseness Lossofvoice(laryngitis)GraduallyworseningcoughthatmaylastforweeksormonthsHeadacheWhatCausesChlamydiaPneumoniae?ThebacteriaChlamydiapneumoniaedamagestheliningoftherespiratorytractincludingthethroat,windpipe,andlungs,causingrespiratorytractinfectionssuchaspneumoniaandbronchitis.C.pneumoniaeisspreadwheninfectedpeoplecoughorsneeze,releasingsmallrespiratorydropletsthatcontainthebacteriathatcanbeinhaledbyothersnearby.Touchingsomethingcoveredwithdropletsfromasickperson’scoughorsneeze,thentouchingone’smouthornosecanalsoresultininfection.ItiscommonforC.pneumoniaetospreadamongpeoplewholivetogether. People

SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkChlamydiapneumoniaeInfectionSectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateChlamydiapneumoniaeInfectionMinusRelatedPagesChlamydiapneumoniaeisatypeofbacteriathatcancauserespiratorytractinfections,suchaspneumonia.C.pneumoniaeisonecauseofcommunity-acquiredpneumoniaorlunginfectionsdevelopedoutsideofahospital.However,noteveryoneexposedtoC.pneumoniaewilldeveloppneumonia.AbouttheDiseaseCauses,howitspreads,riskgroups,signsandsymptoms,prevention…ForCliniciansandLaboratoriansDiseasespecifics,complications,treatment,diagnostictesting,antibioticresistancetrends…SurveillanceandReportingReportingsystem,surveillance,trends,outbreaks…PublicationsChaptersandarticlesaboutC.pneumoniaeandoutbreaks…HowDoYouSayThat?FindpronunciationguidesbelowforcommonwordsassociatedwithC.pneumoniae.Chlamydia—klah-MID-e-aPneumonia—noo-MOAN-yahPneumoniae—noo-MOAN-e-aTracheobronchitis—TRAY-key-o-brahn-KITE-ussPagelastreviewed:January10,2019Contentsource:NationalCenterforImmunizationandRespiratoryDiseases,DivisionofBacterialDiseaseshomeChlamydiapneumoniaeInfectionHomeAbouttheDiseaseexpandCauses,HowItSpreads,&PeopleatIncreasedRiskSigns&SymptomsDiagnosis,Treatment,&ComplicationsPreventionHistory&DiseasePatternsFastFactsForClinicians&LaboratoriansexpandDiseaseSpecificsClinicalFeatures&ComplicationsTreatmentDiagnosticMethodsSpecimenSubmissionforDiagnosticTestingSurveillance&ReportingPublicationsFacebookTwitterLinkedInSASstatsExitNotification/DisclaimerPolicyCloseLinkswiththisiconindicatethatyouareleavingtheCDCwebsite.TheCentersforDiseaseControlandPrevention(CDC)cannotattesttotheaccuracyofanon-federalwebsite.Linkingtoanon-federalwebsitedoesnotconstituteanendorsementbyCDCoranyofitsemployeesofthesponsorsortheinformationandproductspresentedonthewebsite.Youwillbesubjecttothedestinationwebsite'sprivacypolicywhenyoufollowthelink.CDCisnotresponsibleforSection508compliance(accessibility)onotherfederalorprivatewebsite.FormoreinformationonCDC'

Home»DecisionSupportinMedicine»InfectiousDiseasesOVERVIEW:WhateveryclinicianneedstoknowPathogennameandclassificationChlamydiapneumoniae—anintracellularorganismwithacellmembranebutnocellwallInmanyseries,itisthethirdorfourthmostcommoncauseofcommunity-acquiredpneumoniae(CAP).However,giventhedifficultiesinmakinganaccurateetiologicaldiagnosisofinfectionbythismicro-organism,thereisstillsomecontroversyastowhetherornotthisisamajorpathogeninCAP.Co-infectionswithS.pneumoniaeandM.pneumoniaeoccurfrequently.ContinueReadingC.pnemoniaehasbeenimplicatedinquiteanumberofchronicillnesses,suchasatherosclerosis,asthma,arthritis,multiplesclerosis,andmanyothers.However,theevidenceforcausationinmostoftheseisnotstrong.MostoftheempiricantibiotictreatmentsusedforCAPwilltreatC.pneumoniae.Chlamydiaeareobligateintracellularbacterialpathogens.RecenttaxonomicanalysisofthegenusChlamydiahasfoundthattherearetwogenera–ChlamydiaandChlamydophila.Chlamydophilahasthefollowingspecies:C.pecorum,whichcausesinfectionincattle,sheep,andkoalas;C.pneumoniaeandC.psittaci;C.abortus,whichcausesovineandbovineabortion;C.cavieae,whichcausesguineapigconjunctivitis;andC.felis,whichcauseskeratoconjunctivitisincats.C.pneumoniaehasagram-negativecellwallandauniquedevelopmentcyclewithelementary(theinfectiousparticle)andreticulate(theintracellularreplicativeparticle)bodies.Afterinfection,elementarybodies(200-400nmindiameter)attachtothehostcellbyelectrostaticbindingandenterthecellbyendocytosis.Elementarybodies(EB)differentiateintoreticulatebodies(RB)thatundergobinaryfission.Afterabout36hours,thereticulatebodies(RBs)differentiatebackintoelementarybodies(EBs).AlargenumberofEBsaccumulateinthecell(approximately500-1000),yethostcellfunctionisnotaffected.Theselargeaccumulations,ormicrocolonies,arereferredtoasintracytoplasmicinclusions.Duringthisprocess,chlamydialantigensarereleasedontothehostcellsurface,inducingahostimmuneresponse.ReleaseofEBsoccursbyseveralprocesses,includingextrusionoftheinclusion.ItisalsolikelythatC.pneumoniaeente

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ChlamydophilapneumoniaeFromMicrobeWiki,thestudent-editedmicrobiologyresourceJumpto:navigation,searchThisisacuratedpage.ReportcorrectionstoMicrobewiki.AMicrobialBiorealmpageonthegenusChlamydophilapneumoniaeContents1Classification1.1Higherordertaxa1.2Species2DescriptionandSignificance3GenomeStructure4CellStructureandMetabolism5Ecology6Pathology7ApplicationtoBiotechnology8CurrentResearch9ReferencesClassificationHigherordertaxaKingdom:Bacteria;Phylum:Chlamydiae;Order:Chlamydiales;Genus:Chlamydophila;Species:C.pneumoniae;[NCBI]SpeciesNCBI:TaxonomyChlamydophilapneumoniaeDescriptionandSignificanceChlamydophilapneumoniaeisaspeciesofrod-shaped,Gram-negativebacteriathatisknowntobeamajorcauseofpneumonia,asthma,bronchitis,respiratoryinfection,coronaryheartdisease,andatherosclerosisinhumans.Itisanairbornebacteriaandabout50%ofadultsintheUnitedStateshaveevidenceofpreviousinfectionbytheageof20.Similartoviruses,Chlamydophilapneumoniaeisaparasiticorganismthatcannotreproduceoutsideofthehostcellandisthereforedependentonthehealthofthehostcellforsurvival.BeforemoreadvancedresearchtoolsthatcomparedDNAandantigenicmaterialwereinvented,therewasonlyonegenusunderthefamilyChlamydiaceae.ThatgenuswasChlamydia.However,afterfindingverydifferentDNAandantigenicmaterial,anothergenuswasintroducedintothefamily:Chlamydophilawhichmeans"Clamydia-like".Thus,thepreviouslynamedChlamydiapneumoniaewasrenamedChlamydophilapneumoniae[6].GenomeStructureThegenesequenceofChlamydophilapneumoniaeCWL029,thestrainmostcommonintheUnitedStates,hasbeenfullysequenced,aswithmanyotherstrains,in1999.Thegenomecontains1,230,230basepairsofcircularDNA.Thereare1,052proteingenesand43RNAgenes.Therearenoplasmidsthathavebeenidentifiedasofyetwiththisspecies[1,5].CellStructureandMetabolismChlamydophilapneumoniaeexistsinastationary,non-infectiousstateinbetweenhostsknownasaelementarybody(EB).Althoughtheelementarybodyisnotinfectious,ithastheabilitytowithstandenvironmentalstressesuntilitreachesanewhostwhereittransformsintoareticulatebody(RB).T