ChlamydophilapneumoniaeFromMicrobeWiki,thestudent-editedmicrobiologyresourceJumpto:navigation,searchThisisacuratedpage.ReportcorrectionstoMicrobewiki.AMicrobialBiorealmpageonthegenusChlamydophilapneumoniaeContents1Classification1.1Higherordertaxa1.2Species2DescriptionandSignificance3GenomeStructure4CellStructureandMetabolism5Ecology6Pathology7ApplicationtoBiotechnology8CurrentResearch9ReferencesClassificationHigherordertaxaKingdom:Bacteria;Phylum:Chlamydiae;Order:Chlamydiales;Genus:Chlamydophila;Species:C.pneumoniae;[NCBI]SpeciesNCBI:TaxonomyChlamydophilapneumoniaeDescriptionandSignificanceChlamydophilapneumoniaeisaspeciesofrod-shaped,Gram-negativebacteriathatisknowntobeamajorcauseofpneumonia,asthma,bronchitis,respiratoryinfection,coronaryheartdisease,andatherosclerosisinhumans.Itisanairbornebacteriaandabout50%ofadultsintheUnitedStateshaveevidenceofpreviousinfectionbytheageof20.Similartoviruses,Chlamydophilapneumoniaeisaparasiticorganismthatcannotreproduceoutsideofthehostcellandisthereforedependentonthehealthofthehostcellforsurvival.BeforemoreadvancedresearchtoolsthatcomparedDNAandantigenicmaterialwereinvented,therewasonlyonegenusunderthefamilyChlamydiaceae.ThatgenuswasChlamydia.However,afterfindingverydifferentDNAandantigenicmaterial,anothergenuswasintroducedintothefamily:Chlamydophilawhichmeans"Clamydia-like".Thus,thepreviouslynamedChlamydiapneumoniaewasrenamedChlamydophilapneumoniae[6].GenomeStructureThegenesequenceofChlamydophilapneumoniaeCWL029,thestrainmostcommonintheUnitedStates,hasbeenfullysequenced,aswithmanyotherstrains,in1999.Thegenomecontains1,230,230basepairsofcircularDNA.Thereare1,052proteingenesand43RNAgenes.Therearenoplasmidsthathavebeenidentifiedasofyetwiththisspecies[1,5].CellStructureandMetabolismChlamydophilapneumoniaeexistsinastationary,non-infectiousstateinbetweenhostsknownasaelementarybody(EB).Althoughtheelementarybodyisnotinfectious,ithastheabilitytowithstandenvironmentalstressesuntilitreachesanewhostwhereittransformsintoareticulatebody(RB).T