Infectious mononucleosis or mono, an infection usually caused by a virus spread in saliva. Referred to as the kissing disease. Learn the ...YouAreHere:Home→HealthTopics→InfectiousMononucleosisURLofthispage:https://medlineplus.gov/infectiousmononucleosis.htmlInfectiousMononucleosisAlsocalled:Glandularfever,Kissingdisease,Mono,MononucleosisOnthispageBasicsSummaryStartHereDiagnosisandTestsLearnMoreRelatedIssuesSee,PlayandLearnNolinksavailableResearchClinicalTrialsJournalArticlesResourcesFindanExpertForYouChildrenTeenagersPatientHandoutsSummaryInfectiousmononucleosis,or"mono",isaninfectionusuallycausedbytheEpstein-Barrvirus.Thevirusspreadsthroughsaliva,whichiswhyit'ssometimescalled"kissingdisease."Monooccursmostofteninteensandyoungadults.However,youcangetitatanyage.SymptomsofmonoincludeFeverSorethroatSwollenlymphglandsSometimesyoumayalsohaveaswollenspleen.Seriousproblemsarerare.Abloodtestcanshowifyouhavemono.Mostpeoplegetbetterintwotofourweeks.However,youmayfeeltiredforafewmonthsafterward.Treatmentfocusesonhelpingsymptomsandincludesmedicinesforpainandfever,warmsaltwatergarglesandplentyofrestandfluids.StartHereAboutEpstein-BarrVirus(EBV)(CentersforDiseaseControlandPrevention)AlsoinSpanishAboutInfectiousMononucleosis(CentersforDiseaseControlandPrevention)AlsoinSpanishMononucleosis(AmericanAcademyofFamilyPhysicians)AlsoinSpanishDiagnosisandTestsLactateDehydrogenase(LDH)IsoenzymesTest(NationalLibraryofMedicine)AlsoinSpanishLactateDehydrogenase(LDH)Test(NationalLibraryofMedicine)AlsoinSpanishMononucleosis(Mono)Tests(NationalLibraryofMedicine)AlsoinSpanishRelatedIssuesMononucleosis:CanItRecur?(MayoFoundationforMedicalEducationandResearch)AlsoinSpanishX-LinkedLymphoproliferativeDisease(XLP)(NationalInstituteofAllergyandInfectiousDiseases)ClinicalTrialsClinicalTrials.gov:Epstein-BarrVirusInfections(NationalInstitutesofHealth)ClinicalTrials.gov:InfectiousMononucleosis(NationalInstitutesofHealth)JournalArticlesReferencesandabstractsfromMEDLINE/PubMed(NationalLibraryofMedicine)Art