One must consider that the heterophile antibody test results may be negative early in the course of EBV infectious mononucleosis. Positivity ...ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointSpecialty:MultispecialtyAllergy&ImmunologyAnesthesiologyBusinessofMedicineCardiologyCriticalCareDermatologyDiabetes&EndocrinologyEmergencyMedicineFamilyMedicineGastroenterologyGeneralSurgeryHematology-OncologyHIV/AIDSHospitalMedicineInfectiousDiseasesInternalMedicineMultispecialtyNephrologyNeurologyOb/Gyn&Women'sHealthOncologyOphthalmologyOrthopedicsPathology&LabMedicinePediatricsPlasticSurgeryPsychiatryPublicHealthPulmonaryMedicineRadiologyRheumatologyTransplantationUrologyMedicalStudentsNursesPharmacistsResidentsTodayonMedscapeEdition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSLogInSignUpIt'sFree!Edition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSRegisterLogInNoResultsNoResultsSunday,July11,2021ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointclosePleaseconfirmthatyouwouldliketologoutofMedscape.Ifyoulogout,youwillberequiredtoenteryourusernameandpasswordthenexttimeyouvisit.LogoutCancelhttps://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL2Fuc3dlcnMvMjIyMDQwLTIyODAxL3doaWNoLWxhYi1zdHVkaWVzLWFyZS1zcGVjaWZpYy1mb3ItZXBzdGVpbi1iYXJyLXZpcnVzLWVidi1pbmZlY3Rpb3VzLW1vbm9udWNsZW9zaXMtbW9ubw==processing....Drugs&Diseases>InfectiousDiseases>Epstein-BarrVirus(EBV)InfectiousMononucleosis(Mono)Q&AWhichlabstudiesarespecificforEpstein-Barrvirus(EBV)infectiousmononucleosis(mono)?Updated:Apr21,2021Author:KartikaShetty,MD,FACP;ChiefEditor:MichaelStuartBronze,MD more...ReferencesShareEmailPrintFeedbackCloseFacebookTwitterLinkedInGoogle+AnswerHeterophileantibodiesSinceheterophileantibodiestypicallyreturnquickerthanEBVspecificantibodies,itisthetestofchoiceinmostclinicalsettingstodetermineifanindividualhasinfectiousmononucleosis.Reactiveheterophileantibodiesinapatientwiththetypicalsymptom