Empiric treatment with a β-lactam agent should be appropriate. For patients with penicillin allergies, vancomycin is an alternative. Source control with ...ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointSpecialty:MultispecialtyAllergy&ImmunologyAnesthesiologyBusinessofMedicineCardiologyCriticalCareDermatologyDiabetes&EndocrinologyEmergencyMedicineFamilyMedicineGastroenterologyGeneralSurgeryHematology-OncologyHIV/AIDSHospitalMedicineInfectiousDiseasesInternalMedicineMultispecialtyNephrologyNeurologyOb/Gyn&Women'sHealthOncologyOphthalmologyOrthopedicsPathology&LabMedicinePediatricsPlasticSurgeryPsychiatryPublicHealthPulmonaryMedicineRadiologyRheumatologyTransplantationUrologyMedicalStudentsNursesPharmacistsResidentsTodayonMedscapeEdition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSLogInSignUpIt'sFree!Edition:ENGLISHDEUTSCHESPAÑOLFRANÇAISPORTUGUÊSRegisterLogInNoResultsNoResultsSunday,September5,2021ForYouNews&PerspectiveDrugs&DiseasesCME&EducationAcademyVideoDecisionPointclosePleaseconfirmthatyouwouldliketologoutofMedscape.Ifyoulogout,youwillberequiredtoenteryourusernameandpasswordthenexttimeyouvisit.LogoutCancelExpertReviewofAnti-InfectiveTherapyStaphylococcusLugdunensis:TheCoagulase-negativeStaphylococcusYouDon'tWanttoIgnoreElizabethBabu;JohnOropelloDisclosuresExpertRevAntiInfectTher. 2011;9(10):901-907. InThisArticleAbstractandIntroductionEpidemiologyHistoryClinicalFeaturesPathogenesisDiagnosisTreatmentPrognosisExpertCommentary&Five-yearViewReferencesSidebarTreatmentMostisolatesofS.lugdunensisdescribedhavebeensensitivetoanarrayofantimicrobialtherapy.However,therehavebeenisolatedcasereportsofresistancetoerythromycin,[73]streptomycin,[73]tetracycline,[4]penicillin,[74,75]gentamicin,[55]ceftazidime,[55]aminoglycosides[20]andmacrolides.[27]Developmentofresistancetociprofloxacin[67]andrifampininapatientonchronictreatmentforsepticarthritis,vertebralosteomyelitisandaorticandmitralvalveendocarditishasbeendescribed.[76]β-lactamase,theenzymethatconfersre