Substance use disorders can develop whether or not a drug is legal, is socially acceptable, or has an accepted medical use (with or without a prescription).MSDManualPleaseconfirmthatyouarenotlocatedinsidetheRussianFederationYesNoLeavethisSite?Thelinkyouhaveselectedwilltakeyoutoathird-partywebsite.Wedonotcontrolorhaveresponsibilityforthecontentofanythird-partysite.ContinueCancelhoneypotlinkHOMEHEALTHTOPICSCommonHealthTopicsBloodDisordersBone,Joint,andMuscleDisordersBrain,SpinalCord,andNerveDisordersCancerChildren'sHealthIssuesDigestiveDisordersDisordersofNutritionDrugsEar,Nose,andThroatDisordersEyeDisordersFundamentalsHeartandBloodVesselDisordersHormonalandMetabolicDisordersImmuneDisordersInfectionsInjuriesandPoisoningKidneyandUrinaryTractDisordersLiverandGallbladderDisordersLungandAirwayDisordersMen'sHealthIssuesMentalHealthDisordersMouthandDentalDisordersOlderPeople’sHealthIssuesSkinDisordersSpecialSubjectsWomen'sHealthIssuesResourcesVideosFiguresImagesQuizzesCommonMedicalTestsViewAllResourcesSYMPTOMSGeneralAbdomen&DigestiveBleedingBrain&NervousSystemChest&RespiratoryChildren'sSymptomsEyeGenital&UrinaryALLSYMPTOMS>EMERGENCIESCardiacArrestChokingALLEMERGENCIES>RESOURCESAbbreviationsAudio3DModelsCommonMedicalTestsFiguresFirstAidImagesInfographicsLabTestMedicalTermsTheOne-PageManualofHealthPronunciationsQuizzesSelf-AssessmentToolsTablesVideosWeights&MeasuresNEWS5StepstoProtectYoungAthletes'Eyes1in5PatientsonKidneyDialysisSayNotoCOVID-19Vaccine:StudyAHANews:After47Minutes,OneFinalTryResuscitatedHerCancersFarMoreCommoninMedievalTimesThanThoughtViewAllNews>ViewAllNews>ABOUTOverviewHistoryEditorsandtheEditorialProcessPublishingandProductionStaffEditorialBoardContributorsReviewersContentProvidersGlobalMedicalKnowledgeFAQContactUsHealthTopics&ChaptersABCDEFGHIJKLMNOPQRSTUVWXYZHome/MentalHealthDisorders/Substance-RelatedDisorders/.../SubstanceUseDisorders/INTHISTOPICRecreationalandillicitsubstanceuseCausesDrugUserSettingDiagnosisCriteriafordiagnosisTreatmentMoreInformationOT