Familial adenomatous polyposis | Familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is a rare, inherited condition caused by a defect in the adenomatous polyposis coli (APC) gene.Scheduleyourappointmentnowforsafein-personcare.Learnmore:MayoClinicfactsaboutcoronavirusdisease2019(COVID-19)Our COVID-19patient andvisitorguidelines,plustrustedhealthinformationLateston COVID-19vaccination bysite:ArizonapatientvaccinationupdatesArizona,FloridapatientvaccinationupdatesFlorida,RochesterpatientvaccinationupdatesRochesterandMayoClinicHealthSystempatientvaccinationupdatesMCHSSkiptositenavigationSkiptoContentThiscontentdoesnothaveanEnglishversion.ThiscontentdoesnothaveanArabicversion.SectionsforFamilialadenomatouspolyposisSymptoms&causesDiagnosis&treatmentDoctors&departmentsCareatMayoClinicPrintWe'rewelcomingpatientsatMayoClinicSeeoursafetyprecautionsinresponsetoCOVID-19.Requestanappointment.OverviewFamilialadenomatouspolyposis(FAP)isarare,inheritedconditioncausedbyadefectintheadenomatouspolyposiscoli(APC)gene.Mostpeopleinheritthegenefromaparent.Butfor25to30percentofpeople,thegeneticmutationoccursspontaneously.FAPcausesextratissue(polyps)toforminyourlargeintestine(colon)andrectum.Polypscanalsooccurintheuppergastrointestinaltract,especiallytheupperpartofyoursmallintestine(duodenum).Ifuntreated,thepolypsinthecolonandrectumarelikelytobecomecancerouswhenyouareinyour40s.Mostpeoplewithfamilialadenomatouspolyposiseventuallyneedsurgerytoremovethelargeintestinetopreventcancer.Thepolypsintheduodenumalsocandevelopcancer,buttheycanusuallybemanagedbycarefulmonitoringandbyremovingpolypsregularly.Somepeoplehaveamilderformofthecondition,calledattenuatedfamilialadenomatouspolyposis(AFAP).PeoplewithAFAPusuallyhavefewercolonpolyps(anaverageof30)anddevelopcancerlaterinlife.Products&ServicesBook:MayoClinicFamilyHealthBook,5thEditionNewsletter:MayoClinicHealthLetter—DigitalEditionShowmoreproductsfromMayoClinicSymptomsThemainsignofFAPishundredsoreventhousandsofpolypsgrowinginyourcolonandrectum,usuallystartingbyyourmid-teens.Thepolypsarenearly100

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Familial adenomatous polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is characterized by the development of many tens to thousands of adenomas in the rectum and colon ...
Familial Adenomatous Polyposis (FAP) | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is a rare disease where a number of precancerous polyps develop in the large intestine, increasing ...
Familial Adenomatous Polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is a rare inherited cancer predisposition syndrome characterized by hundreds to thousands of precancerous colorectal ...
Familial Adenomatous Polyposis: Background ... | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is the most common adenomatous polyposis syndrome. It is an autosomal dominant inherited disorder ...
Familial adenomatous polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is characterized by the development of many tens to thousands of adenomas in the rectum and colon ...
Familial adenomatous polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is an autosomal-dominant colorectal cancer syndrome, caused by a germline mutation in the adenomatous polyposis coli ...
Familial adenomatous polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is a rare, inherited condition caused by a defect in the adenomatous polyposis coli (APC) gene.
Familial adenomatous polyposis: MedlinePlus Genetics | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is an inherited disorder characterized by cancer of the large intestine (colon ) and rectum. People with the classic type of familial adenomatous polyposis may begin to develop multiple noncancerous (benign) growths (polyps ) in the colon as early as their teenage years.
Familial Adenomatous Polyposis | Familial adenomatous polyposis
Classic familial adenomatous polyposis, called FAP or classic FAP, is a genetic condition. It is diagnosed when a person develops more than 100 adenomatous ...
Familial adenomatous polyposis | Familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated.