Aims: (1) Define the prevalence of selected neurological problems (migraine and epilepsy) and gastrointestinal problems (celiac disease, lactose ...SkiptomaincontentAdvertisementSearchallBMCarticlesSearchDownloadPDFResearcharticleOpenAccessPublished:17December2020Conductdisorderandsomatichealthinchildren:anationwidegeneticallysensitivestudyNóraKerekes ORCID:orcid.org/0000-0002-8854-03991,BtissameZouini2,EmmaKarlsson3,EmmaCederholm4,PaulLichtenstein5,HenrikAnckarsäter6&MariaRåstam7,8 BMCPsychiatryvolume 20,Article number: 595(2020)Citethisarticle809Accesses1AltmetricMetricsdetailsAbstractBackgroundConductdisorder(CD),aseriousbehavioralandemotionaldisorderinchildhoodandadolescence,characterizedbydisruptivebehaviorandbreakingsocietalrules.StudieshaveexploredtheoverlapofCDwithneurodevelopmentalproblems(NDP).ThesomatichealthofchildrenwithNDPhasbeeninvestigated;however,theprevalenceoftheseproblemsinchildrenwithCDhasnotbeensufficientlystudied.HolisticassessmentofchildrenwithCDisrequiredforestablishingeffectivetreatmentstrategies.Aims:(1)Definetheprevalenceofselectedneurologicalproblems(migraineandepilepsy)andgastrointestinalproblems(celiacdisease,lactoseintolerance,diarrhea,andconstipation)inapopulationoftwinsaged9or12;(2)Comparetheprevalenceofsomaticproblemsinthreesubpopulations:(a)childrenwithoutCDorNDP,(b)childrenwithCD,and(c)childrenwithbothCDandNDP;(3)SelecttwinpairswhereatleastonechildscreenedpositiveforCDbutnotNDP(proband)andmapbothchildren’sneurologicalandgastrointestinalproblems.MethodTelephoneinterviewswithparentsof20,302twinsinacross-sectional,nationwide,ongoingstudy.AccordingtotheirscoresontheAutism-Tics,AD/HD,andComorbiditiesinventory,screen-positivechildrenwereselectedanddividedintotwogroups:(1)childrenwithCDOnly,(2)childrenwithCDandatleastoneNDP.ResultsChildrenwithCDhadanincreasedprevalenceofeachneurologicalandgastrointestinalproblem(exceptceliacdisease),andtheprevalenceofsomaticproblemswasfurtherincreasedamongchildrenwithcomorbidCDandNDP.ThepresenceofCD(wit