[11] Small bowel angiodysplasia is the most common cause of obscure GI bleeding (OGIB) in patients older than 50 years old. In contrast, small ...NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutNCBIBookshelf.AserviceoftheNationalLibraryofMedicine,NationalInstitutesofHealth.StatPearls[Internet].TreasureIsland(FL):StatPearlsPublishing;2020Jan-.StatPearls[Internet].ShowdetailsTreasureIsland(FL):StatPearlsPublishing;2020Jan-.SearchtermAngiodysplasiaMaryamAghighi;MehranTaherian;AshishSharma.AuthorInformationAuthorsMaryamAghighi1;MehranTaherian2;AshishSharma3.Affiliations1RWJBarnabasHealth2UniversityatBuffalo,DepartmentofPathology3YumaRegionalMedicalCenterLastUpdate:June23,2020.IntroductionThegastrointestinal(GI)tractisthemostfrequentsiteinthebodyforseveraltypesofabnormalbloodvessels,whichrepresentirregularitiesinthenormalformoftheaffectedarteries,veins,orcapillaries.Vascularabnormalitiescanbebenignormalignantsuchashemangiomasorangiosarcomas,respectively.Also,theycanbecongenital,suchashereditaryhemorrhagictelangiectasiaormostlyacquired,suchasangiodysplasia.[1]Angiodysplasiaisanabnormal,tortuous,dilatedsmallbloodvesselinthemucosalandsubmucosallayersoftheGItract.Theabnormalvesselsconsistofendotheliumwithscantornosmoothmuscle.[2]Angiodysplasiaisthemostfrequentetiologyofsmallbowelbleedingorformerlycalledobscuregastrointestinalbleeding(OGIB)inpatientsmorethan60yearsofage.[3]Angiodysplasiaisnotrelatedtoanyhereditary,skin,orsystemicdiseaseandcanaffectanypartoftheGItract.[4]EtiologyAlthoughtheexactetiologyofangiodysplasiaisunclear,manyideasappearintheliterature,includingage-relateddegenerationofsmallbloodvesselsandalsocardiovascularandpulmonarydisease,whichmaycausehypoperfusionofmicrovesselsleadingtoischemicnecrosisofabnormalvascularlesions.[4] Angiodysplasiacanberelatedtoaorticstenosis.[5]Anotherreportedthecauseofangiodysplasiawasthemucosalhypoperfusionassociatedwithcardiacdisease.[6]InvonWillebranddisease(VWD),therehasbeenbleedingr