Mirror syndrome (MS) is a rare complication of fetal hydrops appearing as a triple edema (fetal, placental as well as maternal) [1], in which ...SkiptomaincontentAdvertisementSearchallBMCarticlesSearchDownloadPDFCasereportOpenAccessPublished:06April2018ResolutionofmaternalMirrorsyndromeaftersuccesfulfetalintrauterinetherapy:acaseseriesAngelChimenea1,LutgardoGarcía-Díaz1,AnaMaríaCalderón1,MaríaMoreno-DeLasHeras1&GuillermoAntiñolo1,2 BMCPregnancyandChildbirthvolume 18,Article number: 85(2018)Citethisarticle7904Accesses4Citations8AltmetricMetricsdetailsAbstractBackgroundMirrorsyndrome(MS)isarareobstetricconditionusuallydefinedasthedevelopmentofmaternaledemainassociationwithfetalhydrops.ThepathogenesisofMSremainsunclearandmaybemisdiagnosedaspre-eclampsia.CasepresentationWereportacaseseriesofMSinwhichfetaltherapy(intrauterinebloodtransfusionandpleuroamnioticshunt)resultedinfetalaswellasmaternalfavourablecoursewithcompleteresolutionoftheconditioninbothmotherandfetus.ConclusionsOurcaseseriesaddnewevidencetosupportthatearlydiagnosisofMSfollowedbyfetaltherapyandclinicalmaternalsupportarecriticalforagoodoutcome.PeerReviewreportsBackgroundMirrorsyndrome(MS)isararecomplicationoffetalhydropsappearingasatripleedema(fetal,placentalaswellasmaternal)[1],inwhichthemother“mirrors”thehydropicfetus.Thissyndromewasfirstdescribedin1892bytheScottishobstetricianJohnWilliamBallantyne[2].Therehavebeenmultiplefeto-placentaldiseasesrelatedtoMS,thatcanbeclassifiedintodiversegroupsbasedondifferentetiologies[3]:cardiacfailureassociatedwithfetalanemia(e.g.ParvovirusB19[4],erytroblastosis[5],fetalalloimmunethrombocytopenia[6],hemoglobinBart’sdisease[7]);high-outputcardiacfailureassociatedwithshunting(e.g.chorioangioma[8],twintotwintransfusionsyndrome[9,10,11,12,13]);andfetalanomalies(e.g.fetalarrhythmias[14],CHAOSsyndrome[15]).MSmaternalclinicalpictureincludesperipheraledema,uterinedistensionandrapidweightgain[3].Thosenonspecificclinicalfeaturesmayleadtoamisdiagnosisofpre-eclampsia,delayingdiagnosis