Once clinical signs have been controlled, the cats should be vaccinated. Vaccination should be considered for cats at risk of exposure to infection. Vaccination ...ArticlePDFAvailableLiteratureReviewChlamydophilaFelisInfection:ABCDGuidelinesonPreventionandManagementAugust2009JournalofFelineMedicine&Surgery11(7):605-9DOI:10.1016/j.jfms.2009.05.009SourcePubMedAuthors:TimothyJohnGruffydd-JonesUniversityofBristolDianeDAddieUniversityofGlasgowSándorBelákSwedishUniversityofAgriculturalSciencesCorineBoucrautScanelisShowall16authorsHideDownloadfull-textPDFReadfull-textDownloadfull-textPDFReadfull-textDownloadcitationCopylinkLinkcopiedReadfull-textDownloadcitationCopylinkLinkcopiedCitations(40)References(21)AbstractChlamydophilafelisisaGram-negativebacteriumanditsprimarytargetistheconjunctiva.Thebacteriumdoesnotsurviveoutsidethehost.INFECTION:Transmissionrequiresclosecontactbetweencats;ocularsecretionsareprobablythemostimportantbodyfluidforinfection.Mostcasesoccurincatsunder1yearofage.Chlamydophilafelisistheinfectiousorganismmostfrequentlyassociatedwithconjunctivitis.Unilateraloculardiseasegenerallyprogressestobecomebilateral.Therecanbeintenseconjunctivitiswithextremehyperaemiaofthenictitatingmembrane,blepharospasmandoculardiscomfort.Transientfever,inappetenceandweightlossmayoccurshortlyafterinfection,althoughmostcatsremainwellandcontinuetoeat.PCRtechniquesarenowpreferredfordiagnosingCfelisinfection.Ocularswabsaregenerallyused.Inunvaccinatedcats,antibodydetectioncanbeusedtoindicateinfection.Tetracyclinesaregenerallyregardedastheantibioticsofchoice.Doxycyclinehastheadvantageofrequiringonlysingledailyadministrationandisgivenatadoseof10mg/kgorally.Vaccinationshouldbeconsideredifthereisahistoryofconfirmedchlamydialdiseaseinashelter.Singlehousingandroutinehygienemeasuresshouldsufficetoavoidcross-infection.Catsmaintainedtogetherforlongertermsshouldbevaccinatedregularly.InbreedingcatterieswhereCfelisinfectionisendemic,thefirststepshouldbetotreatallcatswithdoxycyclineforatleast4week