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1. Hodgkin lymphoma

Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called B lymphocytes, although the exact reason why this happens ...SkiptomaincontentHomeHealthAtoZHodgkinlymphomaBacktoHodgkinlymphomaCauses-HodgkinlymphomaContentsOverviewSymptomsCausesDiagnosisTreatmentComplicationsHodgkinlymphomaiscausedbyachange(mutation)intheDNAofatypeofwhitebloodcellcalled Blymphocytes,althoughtheexactreasonwhythishappensisn'tknown.TheDNAgivesthecellsabasicsetofinstructions,suchaswhentogrowandreproduce.ThemutationintheDNAchangestheseinstructionssothecellskeepgrowing,causingthemtomultiplyuncontrollably.Theabnormallymphocytesusuallybegintomultiplyinoneormorelymphnodesinaparticularareaofthebody,suchasyourneckorgroin.Overtime,it'spossiblefortheabnormallymphocytestospreadintootherpartsofyourbody,suchasyour:bonemarrowspleenliverskinlungsWho'smostatrisk?Whilethe causeoftheinitialmutationthattriggersHodgkinlymphomaisunknown,anumberoffactorscanincreaseyourriskofdevelopingthecondition.Theseinclude:havingamedicalconditionthatweakensyourimmunesystem,suchasHIVhavingmedicaltreatmentthatweakensyourimmunesystem–forexample,takingmedicationtosuppressyourimmunesystemafteranorgantransplantbeingpreviouslyexposedtotheEpstein-Barrvirus(EBV)– acommonvirusthatcausesglandularfeverhavingpreviouslyhad non-Hodgkinlymphoma,possiblybecauseoftreatmentwith chemotherapy orradiotherapybeingveryoverweight(obese) – thismaybemoreofariskfactorinwomenthanmenHodgkinlymphomaisn'tinfectiousand isn'tthoughtto runinfamilies.Althoughyour riskis increasedifafirst-degreerelative(parent,siblingorchild)hashadlymphoma,it'snotclearifthisisbecauseofaninheritedgeneticfault or lifestylefactors.Hodgkinlymphomacanoccuratanyage,althoughmostcasesarediagnosedinpeopleintheirearly20sor70s.Theconditionisslightlymorecommoninmenthanwomen.Pagelastreviewed:20September2018Nextreviewdue:20September2021Previous:SymptomsNext:Diagnosis



2. Hodgkin's Disease: Symptoms, Diagnosis, and Treatment

Hodgkin's disease (HD) is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get ...Hodgkin’sDiseaseMedicallyreviewedbyYaminiRanchod,Ph.D.,M.S.—WrittenbyJaimeHerndon,MS,MPH,MFA—UpdatedonSeptember17,2018SymptomsDiagnosisTreatmentRisksOutlookWhatisHodgkin’sdisease?Hodgkin’sdisease(HD)isatypeoflymphoma,whichisabloodcancerthatstartsinthelymphaticsystem.Thelymphaticsystemhelpstheimmunesystemgetridofwasteandfightinfections.HDisalsocalledHodgkindisease,Hodgkinlymphoma,andHodgkin’slymphoma.HDoriginatesinwhitebloodcellsthathelpprotectyoufromgermsandinfections.Thesewhitebloodcellsarecalledlymphocytes.InpeoplewithHD,thesecellsgrowabnormallyandspreadbeyondthelymphaticsystem.Asthediseaseprogresses,itmakesitmoredifficultforyourbodytofightinfections.HDcanbeeitherclassicHodgkin’sdiseaseornodularlymphocyticpredominantHodgkin’slymphoma(NLPHL).ThetypeofHDisbasedonthetypesofcellsinvolvedinyourconditionandtheirbehavior.ThemaincauseofHDisn’tknown.ThediseasehasbeenlinkedtoDNAmutations,orchanges,aswellastotheEpstein-Barrvirus(EBV),whichcausesmononucleosis.HDcanoccuratanyage,butitmostcommonlyaffectspeoplebetweenages15and40andpeopleoverage55.WhatarethesymptomsofHodgkin’sdisease?ThemostcommonsymptomofHDisswellingofthelymphnodes,whichcausesalumptoformundertheskin.Thislumpusuallyisn’tpainful.Itmayforminoneormoreofthefollowingareas:onthesideoftheneckinthearmpitaroundthegroinOthersymptomsofHDinclude:nightsweatsitchyskinfeverfatigueunintendedweightlosspersistentcough,troublebreathing,chestpainpaininthelymphnodesafterconsumingalcoholenlargedspleenCallyourdoctorrightawayifyouhaveanyofthesesymptoms.Theycanbesignsofotherconditions,andit’simportanttogetanaccuratediagnosis.HowisHodgkin’sdiseasediagnosed?TodiagnoseHD,yourdoctorwillperformaphysicalexamandaskyouaboutyourmedicalhistory.Yourdoctorwillalsoordercertaintestssotheycanmakeaproperdiagnosis.Thefollowingtestsmaybedone:imagingtests,suchasX-raysorCTscanslymphnodebiopsy,whichinv



3. Hodgkin lymphoma

In Hodgkin lymphoma, B-lymphocytes (a particular type of lymphocyte) start to multiply in an abnormal way and begin to collect in certain parts of the lymphatic​ ...SkiptomaincontentHomeHealthAtoZBacktoHealthAtoZOverview-HodgkinlymphomaContentsOverviewSymptomsCausesDiagnosisTreatmentComplicationsHodgkinlymphomaisanuncommoncancerthatdevelopsinthelymphaticsystem,whichisanetworkofvesselsandglandsspreadthroughoutyourbody.Thelymphaticsystemispartofyourimmunesystem.Clearfluidcalledlymphflowsthroughthelymphaticvesselsandcontainsinfection-fightingwhitebloodcells,knownaslymphocytes.InHodgkinlymphoma,B-lymphocytes(aparticulartypeoflymphocyte)starttomultiplyinanabnormalwayandbegintocollectincertainpartsofthelymphaticsystem,suchasthelymphnodes(glands).Theaffectedlymphocyteslosetheirinfection-fightingproperties,makingyoumorevulnerabletoinfection.ThemostcommonsymptomofHodgkinlymphomaisapainlessswellinginalymphnode,usuallyintheneck,armpitorgroin.ReadmoreaboutthesymptomsofHodgkinlymphoma.Information:CoronavirusadviceGetadviceaboutcoronavirusandcancer:Macmillan:CoronavirusguidanceforpeoplewithcancerCancerResearchUK:CoronavirusandcancerWhoisaffected?Hodgkinlymphoma candevelopatanyage,butitmostlyaffectsyoungadultsintheirearly20sandolderadultsovertheageof70.Slightlymorementhanwomenareaffected.Around2,100peoplearediagnosedwithHodgkinlymphomaintheUKeachyear.WhatcausesHodgkinlymphoma?TheexactcauseofHodgkinlymphomaisunknown.However,yourriskofdevelopingtheconditionisincreasedif:you haveamedicalconditionthatweakensyourimmunesystemyoutakeimmunosuppressantmedicationyou'vepreviouslybeenexposedto acommonviruscalledtheEpstein-Barrvirus – whichcausesglandularfeverYoualsohaveanincreasedriskofdevelopingHodgkinlymphomaifafirst-degreerelative(parent,siblingorchild)hashadthecondition.ReadmoreaboutthecausesofHodgkinlymphoma.HowHodgkinlymphomaisdiagnosedTheonlywaytoconfirmadiagnosisofHodgkinlymphomaisbycarryingoutabiopsy.Thisisaminorsurgicalprocedurewhere asampleofaffectedlymphnodetissueisremovedandstudi



4. Hodgkin Lymphoma

Hodgkin lymphoma is sometimes called Hodgkin's disease. The name Hodgkin comes from the doctor who first described this cancer. The disease usually starts in ...HomeHodgkinlymphomaDownloadorPrintPDFHodgkinlymphomaHodgkinlymphomaisabloodcancerthatbeginsinthewhitebloodcellscalledlymphocytes.Itisoneofthetwomaingroupsoflymphoma.Theothergroupisnon-Hodgkinlymphoma.HodgkinlymphomaissometimescalledHodgkin’sdisease.ThenameHodgkincomesfromthedoctorwhofirstdescribedthiscancer.Thediseaseusuallystartsinalymphnodeatoneormoreplacesinthebody.Itcanspreadthroughthelymphaticsystemtootherlymphtissue,particularlythespleenandbonemarrow.Becausethelymphaticsystemisanetworkthroughoutthebody,Hodgkinlymphomacanappearinseveralpartsofthebodyatthesametime.Sometimes,Hodgkinlymphomaspreadsoutsidethelymphaticsystemtoformatumourinotherorgans,suchastheliverorlung.Thisisknownasextranodaldisease.Learnmoreabout:Whatisbloodcancer?ThelymphaticsystemTheroleofbloodcellsTypesofHodgkinlymphomaWhogetsHodgkinlymphoma?WhatcausesHodgkinlymphoma?Whatisnon-Hodgkinlymphoma?Whatisbloodcancer?Cancerisadiseaseofthecells,andcellsarethebody’sbasicbuildingblocks–theymakeuptissuesandorgans.Thebodyconstantlymakesnewcellstohelpusgrow,replaceworn-outtissueandhealinjuries.Normally,cellsmultiplyanddieinanorderlyway,sothateachnewcellreplacesonelost.Cancerdevelopswhencellsbecomeabnormalandkeepgrowing.Whenacancerbeginsinabnormalbloodcells,itisknownasabloodcancer.Thethreemaingroupsofbloodcancersarelymphoma,leukaemiaandmyeloma.Lymphomaiscancerofthebody’slymphaticsystem. Inlymphoma,abnormalwhitebloodcellscalledlymphocytesgrowandmultiplyuncontrollablyandcanformalump(tumour),usuallyinalymphnode.Iftheseabnormallymphocytescontinuetobuildup,theycanspreadthroughthelymphandbloodvesselstoformatumourinanotherpartofthelymphaticsystemor,sometimes,inanorganoutsidethelymphaticsystem,suchastheliverorlung.Astheabnormallymphocytesreplacenormalcells,thebody’simmunesystemoftenbecomeslessabletoresistandfightinfections.Sometimesothertypesofcancerspreadt



5. Hodgkin Disease

YouAreHere:Home→HealthTopics→HodgkinDiseaseURLofthispage:https://medlineplus.gov/hodgkindisease.htmlHodgkinDiseaseAlsocalled:HodgkinlymphomaOnthispageBasicsSummaryStartHereDiagnosisandTestsPreventionandRiskFactorsTreatmentsandTherapiesLearnMoreLivingWithRelatedIssuesSee,PlayandLearnNolinksavailableResearchStatisticsandResearchClinicalTrialsJournalArticlesResourcesFindanExpertForYouChildrenTeenagersPatientHandoutsSummaryHodgkindiseaseisatypeoflymphoma.Lymphomaisacancerofapartoftheimmunesystemcalledthelymphsystem.ThefirstsignofHodgkindiseaseisoftenanenlargedlymphnode.Thediseasecanspreadtonearbylymphnodes.Lateritmayspreadtothelungs,liver,orbonemarrow.Theexactcauseisunknown.Hodgkindiseaseisrare.SymptomsincludePainlessswellingofthelymphnodesintheneck,armpits,orgroinFeverandchillsNightsweatsWeightlossLossofappetiteItchyskinTodiagnoseHodgkindisease,doctorsuseaphysicalexamandhistory,bloodtests,andabiopsy.Treatmentdependsonhowfarthediseasehasspread.Itoftenincludesradiationtherapyorchemotherapy.Theearlierthediseaseisdiagnosed,themoreeffectivethetreatment.Inmostcases,Hodgkindiseasecanbecured.NIH:NationalCancerInstituteStartHereGeneralInformationaboutAdultHodgkinLymphoma(NationalCancerInstitute)AlsoinSpanishHodgkin'sLymphoma(MayoFoundationforMedicalEducationandResearch)WhatIsHodgkinDisease?(AmericanCancerSociety)AlsoinSpanishDiagnosisandTestsBloodCountTests:MedlinePlusHealthTopic(NationalLibraryofMedicine)AlsoinSpanishBoneMarrowTest(NationalLibraryofMedicine)AlsoinSpanishHowIsHodgkinDiseaseDiagnosed?(AmericanCancerSociety)AlsoinSpanishNeedleBiopsy(MayoFoundationforMedicalEducationandResearch)AlsoinSpanishPDL1(Immunotherapy)Tests(NationalLibraryofMedicine)AlsoinSpanishStagesofAdultHodgkinLymphoma(NationalCancerInstitute)AlsoinSpanishStagesofChildhoodHodgkinLymphoma(NationalCancerInstitute)AlsoinSpanishPreventionandRiskFactorsWhatAretheRiskFactorsforHodgkinDisease?(AmericanCancerSociety)AlsoinSpanishTreatmentsandTherapiesBoneMarrowTransplantation:MedlinePlusHealthTopic(NationalLi



6. Hodgkin Lymphoma

Hodgkin lymphoma (Hodgkin disease) is a cancer that starts in white blood cells called lymphocytes. Lymphocytes are part of the body's immune system.Whatpatientsandcaregiversneedtoknowabout cancer,coronavirus,andCOVID-19.CloseCriticalAlertBannerSearchVerenespañolCancerA-ZHodgkinLymphomaHodgkinlymphoma(Hodgkindisease)isacancerthatstartsinwhitebloodcellscalledlymphocytes.Lymphocytesarepartofthebody’simmunesystem.AboutHodgkinLymphomaLearnaboutnewresearchandtreatments,keystatistics,andtypesofHodgkinlymphomahere.Causes,RiskFactors,andPreventionLearnmoreaboutthecauses,riskfactors&preventionofHodgkinLymphoma,includingwhatyoumightbeabletodotoloweryourrisk.EarlyDetection,Diagnosis,andStagingLearnmoreaboutdiagnosingandstagingHodgkinLymphoma,includinghowtodetectHodgkindiseaseearlyandrecognizingsignsandsymptomsofthedisease.TreatingHodgkinLymphomaReadabouttreatmentoptionsforHodgkinDiseaseincludingtreatmentinchildrenandduringpregnancy.Alsoreadaboutpossiblesideeffectsoftreatment.AfterTreatmentFindoutaboutlifeafterHodgkinlymphomacancertreatment,suchasfollow-upvisitsandtests,long-termsideeffects,andtheriskofsecondcancers.EasyReadingIfYouHaveHodgkinLymphomaThisshortsimpleguidetoHodgkinlymphomacanhelpanswerimportantquestionssuchaswhattestsareneeded,treatmentoptions,andpossiblesideeffects.Thisinformationispossiblethankstopeoplelikeyou.Wedependondonationstokeepourcancerinformationavailableforthepeoplewhoneeditmost.DonateTodayDownloadablePDFsDownloadfreePDFsofourHodgkindiseaseinformationAboutandKeyStatisticsCauses,Risks,PreventionDetection,Diagnosis,StagingTreatmentandSideEffectsNextStepsAfterTreatmentMoreResourcesReadmoreUnderstandingYourDiagnosisReadmoreTreatments&SideEffectsReadmoreSurvivorship:During&AfterTreatmentReadmorePrograms&ServicesNews&StoriesReadMoreLatestCancerNewsReadMoreStoriesofHopeReadMoreACSResearchNewsBackToTopClose*CloseImageofPreviousNextCloseCloseSelectAHopeLodge



7. What Is Hodgkin Lymphoma?

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) accounts for about 5% of cases. The cancer cells in NLPHL are large cells called popcorn ...Whatpatientsandcaregiversneedtoknowabout cancer,coronavirus,andCOVID-19.CloseCriticalAlertBannerSearchVerenespañol|Downloadthistopic[PDF]AboutHodgkinLymphomaWhatIsHodgkinLymphoma?KeyStatisticsforHodgkinLymphomaWhat’sNewinHodgkinLymphomaResearchandTreatment?CancerA-ZHodgkinLymphomaAboutHodgkinLymphomaWhatIsHodgkinLymphoma?Cancerstartswhencellsstarttogrowoutofcontrol.Cellsinnearlyanypartofthebodycanbecomecancer,andcanthenspreadtootherpartsofthebody.Tolearnmoreabouthowcancersstartandspread,seeWhatIsCancer?Lymphomasarecancersthatstartinwhitebloodcellscalledlymphocytes.Thereare2maintypesoflymphoma:Hodgkinlymphoma(HL)Non-Hodgkinlymphoma(NHL)Theybehave,spread,andrespondtotreatmentdifferently,soit'simportantforyoutoknowwhichoneyouhave.ThisinformationisaboutHodgkinlymphoma.Tolearnabouttheothertype,seeNon-HodgkinLymphoma.ThelymphsystemTounderstandwhatHodgkinlymphomais,ithelpstoknowaboutthelymphsystem(alsoknownasthelymphaticsystem).Thelymphsystemispartoftheimmunesystem,whichhelpsfightinfectionsandsomeotherdiseases.Thelymphsystemalsohelpscontroltheflowoffluidsinthebody.Thelymphsystemismadeupmainlyofcellscalledlymphocytes,atypeofwhitebloodcell.Thereare2maintypesoflymphocytes:Blymphocytes(Bcells):Bcellsmakeproteinscalledantibodiestohelpprotectthebodyfromgerms(bacteriaandviruses).Tlymphocytes(Tcells):TherearemanytypesofTcells.SomeTcellsdestroygermsorabnormalcellsinthebody.OtherTcellshelpboostorslowtheactivityofotherimmunesystemcells.HodgkinlymphomausuallystartsinBlymphocytes.StartandspreadofHodgkinlymphomaLymphtissueisinmanypartsofyourbody,soHodgkinlymphomacanstartalmostanywhere. Themajorsitesoflymphoidtissueare:Lymphnodes:Lymphnodesarebean-sizedcollectionsoflymphocytesandotherimmunesystemcells.They'refoundthroughoutthebody,includinginsidethechest,abdomen(belly),andpelvis.They'reconnectedtoeachotherbyasystemoflymphaticvessels.Lymphvess



8. Hodgkin lymphoma

Hodgkin lymphoma (HL) is a type of lymphoma, in which cancer originates from a specific type of white blood cells called lymphocytes, where multinucleated ...HodgkinlymphomaFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchTypeofbloodandimmune-systemcancerMedicalconditionHodgkinlymphomaOthernamesHodgkin'slymphoma,Hodgkin'sdisease[1]MicrographshowingHodgkinlymphoma(Fieldstain)SpecialtyHematologyandoncologySymptomsFever,nightsweats,weightloss,non-painfulenlargelymphnodes[2]RiskfactorsEpstein–Barrvirus,familyhistory,HIV/AIDS[2][3]DiagnosticmethodLymphnodebiopsy[2]TreatmentChemotherapy,radiationtherapy,stemcelltransplant,[4]immunotherapyPrognosisFive-yearsurvivalrate86%(USA)[5]Frequency574,000(affectedduring2015)[6]Deaths23,900(2015)[7]Hodgkinlymphoma(HL)isatypeoflymphoma,inwhichcanceroriginatesfromaspecifictypeofwhitebloodcellscalledlymphocytes,wheremultinucleatedReed–Sternbergcells(RScells)arepresentinthepatient'slymphnodes.[2][8]Symptomsmayincludefever,nightsweats,andweightloss.[2]Oftentherewillbenon-painfulenlargedlymphnodesintheneck,underthearm,orinthegroin.[2]Thoseaffectedmayfeeltiredorbeitchy.[2]TherearetwomajortypesofHodgkinlymphoma:classicHodgkinlymphomaandnodularlymphocyte-predominantHodgkinlymphoma.[5]AbouthalfofcasesofHodgkinlymphomaareduetoEpstein–Barrvirus(EBV)andthesearegenerallytheclassicform.[3][9]OtherriskfactorsincludeafamilyhistoryoftheconditionandhavingHIV/AIDS.[2][3]DiagnosisisconductedbyconfirmingthepresenceofcancerandidentifyingRScellsinlymphnodebiopsies.[2]Thevirus-positivecasesareclassifiedasaformoftheEpstein-Barrvirus-associatedlymphoproliferativediseases.[10]Hodgkinlymphomamaybetreatedwithchemotherapy,radiationtherapy,andstemcelltransplant.[4]Thechoiceoftreatmentoftendependsonhowadvancedthecancerhasbecomeandwhetherornotithasfavorablefeatures.[4]Inearlydisease,acureisoftenpossible.[11]IntheUnitedStates,86%ofpeoplediagnosedwithHodgkinLymphomasurvivefor5yearsorlonger.[5]Forthoseundertheageof20,ratesofsurvivalare97%.[12]Radiationandsom



9. Hodgkin's lymphoma (Hodgkin's disease)

Lymph node clusters ... Hodgkin's lymphoma — formerly known as Hodgkin's disease — is a cancer of the lymphatic system, which is part of your ...COVID-19:Advice,updatesandvaccineoptionsWeareopenforsafein-personcare.Learnmore:MayoClinicfactsaboutcoronavirusdisease2019(COVID-19)OurCOVID-19patientandvisitorguidelines,plustrustedhealthinformationLateston COVID-19vaccination bysite:ArizonapatientvaccinationupdatesArizona,FloridapatientvaccinationupdatesFlorida,RochesterpatientvaccinationupdatesRochesterandMayoClinicHealthSystempatientvaccinationupdatesMCHSSkiptositenavigationSkiptoContentThiscontentdoesnothaveanEnglishversion.ThiscontentdoesnothaveanArabicversion.SectionsforHodgkin'slymphoma(Hodgkin'sdisease)Symptoms&causesDiagnosis&treatmentDoctors&departmentsCareatMayoClinicPrintOverviewLymphaticsystemOpenpop-updialogboxCloseLymphaticsystemLymphaticsystemYourbody'slymphaticsystemispartofyourimmunesystem,whichprotectsyouagainstinfectionanddisease.Thelymphaticsystemincludesyourspleen,thymus,lymphnodesandlymphchannels,aswellasyourtonsilsandadenoids.LymphnodeclustersOpenpop-updialogboxCloseLymphnodeclustersLymphnodeclustersLymphnodesarebean-sizedcollectionsoflymphocytes.About600ofthesenodesclusterthroughoutthelymphaticsystem,forexample,neartheknee,groin,neckandarmpits.Thenodesareconnectedbyanetworkoflymphaticvessels.Hodgkin'slymphoma—formerlyknownasHodgkin'sdisease—isacancerofthelymphaticsystem,whichispartofyourimmunesystem.Itmayaffectpeopleofanyage,butismostcommoninpeoplebetween20and40yearsoldandthoseover55.InHodgkin'slymphoma,cellsinthelymphaticsystemgrowabnormallyandmayspreadbeyondit.Hodgkin'slymphomaisoneoftwocommontypesofcancersofthelymphaticsystem.Theothertype,non-Hodgkin'slymphoma,isfarmorecommon.AdvancesindiagnosisandtreatmentofHodgkin'slymphomahavehelpedgivepeoplewiththisdiseasethechanceforafullrecovery.TheprognosiscontinuestoimproveforpeoplewithHodgkin'slymphoma.Hodgkin'slymphomacareatMayoClinicProducts&ServicesBook:MayoClinicFamilyHealthBook,5thEditionMayoClinic



10. 霍奇金淋巴瘤

霍奇金氏淋巴瘤(英語:Hodgkin lymphoma (HL))又稱霍奇金氏病、何杰金氏病,或何杰金氏淋巴瘤,為淋巴瘤的一型,是一種淋巴細胞的癌變,症狀包含發燒、夜間盜汗( ...霍奇金淋巴瘤維基百科,自由的百科全書跳至導覽跳至搜尋此條目的引用需要進行清理,使其符合格式。

(2012年5月15日)參考文獻應符合正確的引用、腳註及外部連結格式。

維基百科中的醫療相關內容僅供參考,詳見醫學聲明。

如需醫療服務或可靠意見,請諮詢專業人士。

Hodgkin'slymphoma中東呼吸綜合症的顯微鏡照片(血樣已被染色).類型淋巴瘤肇因人類皰疹病毒感染[*]分類和外部資源醫學專科腫瘤學ICD-10C81ICD-9-CM201ICD-O(英語:InternationalClassificationofDiseasesforOncology)9650/3-9667/3OMIM[1]DiseasesDB5973MedlinePlus000580eMedicinemed/1022PatientUK(英語:PatientUK)hodgkins-lymphoma-pro霍奇金淋巴瘤MeSHD006689Orphanet98293[編輯此條目的維基數據]霍奇金氏淋巴瘤(英語:Hodgkinlymphoma(HL))又稱霍奇金氏病、何杰金氏病,或何杰金氏淋巴瘤[1],為淋巴瘤的一型,是一種淋巴細胞的癌變[2],症狀包含發燒、夜間盜汗(英語:Nightsweats),以及體重減輕[3],常見頸部、上臂,以及鼠蹊部淋巴結無痛腫大[3],患者同時也可能會感到疲憊或搔癢[3]。

約半數的何杰金氏淋巴瘤是因EB病毒引起[4],其他危險因子包含家族有相關病史,或是個人曾受HIV感染[3][4]。

何杰金氏淋巴瘤主要分為典型(classicalHodgkinlymphoma)及結節樣淋巴細胞為主型(英語:nodularlymphocyte-predominantHodgkinlymphoma)兩種[5],可以藉由尋找淋巴結中的何杰金氏淋巴細胞協助診斷,例如RS細胞(英語:Reed–Sternbergcells)[3]。

何杰金氏淋巴瘤可以藉由化學療法、放射線療法,以及骨髓移植治療[6],治療的選擇一般藉由疾病的進展程度,以及其特性進行判斷[6]。

在疾病初期,治癒率通常較高[7],在美國,此疾病的五年存活率約為86%[5],20歲以下的患者存活率更高達97%[8]。

但放療及化療藥物可能增加日後罹患其他癌症、心血管疾病,以及肺部疾病的風險[7]。

2015年,全球約有57.4萬人罹患何杰金氏淋巴瘤,其中約2.39萬人死於此病[9][10],在美國,0.2%的人在一生中的某一時間點有罹患過此一疾病[5]此疾病最常於20至40歲之間診斷出來[5]。

何杰金氏淋巴瘤命名自英國醫師湯瑪士·何杰金(英語:ThomasHodgkin),他於1832年首次描述了此一疾病[7][11][12][13]。

目錄1成因2療法3在淋巴瘤分類中的地位4患此病的名人5信息來源6延伸閱讀7外部連結成因[編輯]霍奇金淋巴瘤病因至今不明,約50%患者的RS細胞中可檢出EB病毒的基因組片段,但兩者是否有相關和詳細機制學界還有爭議。

已知具有免疫缺陷和自體免疫性疾病的患者霍奇金淋巴瘤發病機率較高。

療法[編輯]不論病人在疾病的哪一階段被發現並得到治療,5年生存率都在85%以上。

早期治療(第一期或第二期)效果可能更好。

年輕病人往往能在治療後生存40年甚至更久。

放療、化療會使患者在治療40年後增加患心臟病、二次癌症和肺病的風險。

[14]目前有三種流行的療法:ABVD化療法:1970年代誕生於義大利,是目前在美國醫療界最流行的療法。

典型的療程長度是6-8個月,但也可能更長。

命名的四個字母來自於療法的四個用藥阿黴素、博來黴素、敏畢瘤凍晶、達卡巴仁。

斯坦福五療法:1988年誕生。

它的化療療程通常是ABVD的一半,但是用藥劑量更大。

通常放療也是療程的一部分。

義大利研究人員發現,該療法效果不及ABVD。

BEACOPP化療法:由德國霍普金斯研究組發明,流行於歐洲。

這種療法主要針對第2期以後的患者。

用藥包括:阿黴素、博來黴素、長春花新鹼、癌德星/丙卡巴肼、依託泊甙、強的松。

研究表明,此療法對非早期患者的治癒



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