Hodgkin lymphoma (HL) is a type of lymphoma, in which cancer originates from a specific type of white blood cells called lymphocytes, where multinucleated ...HodgkinlymphomaFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchTypeofbloodandimmune-systemcancerMedicalconditionHodgkinlymphomaOthernamesHodgkin'slymphoma,Hodgkin'sdisease[1]MicrographshowingHodgkinlymphoma(Fieldstain)SpecialtyHematologyandoncologySymptomsFever,nightsweats,weightloss,non-painfulenlargelymphnodes[2]RiskfactorsEpstein–Barrvirus,familyhistory,HIV/AIDS[2][3]DiagnosticmethodLymphnodebiopsy[2]TreatmentChemotherapy,radiationtherapy,stemcelltransplant,[4]immunotherapyPrognosisFive-yearsurvivalrate86%(USA)[5]Frequency574,000(affectedduring2015)[6]Deaths23,900(2015)[7]Hodgkinlymphoma(HL)isatypeoflymphoma,inwhichcanceroriginatesfromaspecifictypeofwhitebloodcellscalledlymphocytes,wheremultinucleatedReed–Sternbergcells(RScells)arepresentinthepatient'slymphnodes.[2][8]Symptomsmayincludefever,nightsweats,andweightloss.[2]Oftentherewillbenon-painfulenlargedlymphnodesintheneck,underthearm,orinthegroin.[2]Thoseaffectedmayfeeltiredorbeitchy.[2]TherearetwomajortypesofHodgkinlymphoma:classicHodgkinlymphomaandnodularlymphocyte-predominantHodgkinlymphoma.[5]AbouthalfofcasesofHodgkinlymphomaareduetoEpstein–Barrvirus(EBV)andthesearegenerallytheclassicform.[3][9]OtherriskfactorsincludeafamilyhistoryoftheconditionandhavingHIV/AIDS.[2][3]DiagnosisisconductedbyconfirmingthepresenceofcancerandidentifyingRScellsinlymphnodebiopsies.[2]Thevirus-positivecasesareclassifiedasaformoftheEpstein-Barrvirus-associatedlymphoproliferativediseases.[10]Hodgkinlymphomamaybetreatedwithchemotherapy,radiationtherapy,andstemcelltransplant.[4]Thechoiceoftreatmentoftendependsonhowadvancedthecancerhasbecomeandwhetherornotithasfavorablefeatures.[4]Inearlydisease,acureisoftenpossible.[11]IntheUnitedStates,86%ofpeoplediagnosedwithHodgkinLymphomasurvivefor5yearsorlonger.[5]Forthoseundertheageof20,ratesofsurvivalare97%.[12]Radiationandsom