Lymph node clusters ... Hodgkin's lymphoma — formerly known as Hodgkin's disease — is a cancer of the lymphatic system, which is part of your ...COVID-19:Advice,updatesandvaccineoptionsWeareopenforsafein-personcare.Learnmore:MayoClinicfactsaboutcoronavirusdisease2019(COVID-19)OurCOVID-19patientandvisitorguidelines,plustrustedhealthinformationLateston COVID-19vaccination bysite:ArizonapatientvaccinationupdatesArizona,FloridapatientvaccinationupdatesFlorida,RochesterpatientvaccinationupdatesRochesterandMayoClinicHealthSystempatientvaccinationupdatesMCHSSkiptositenavigationSkiptoContentThiscontentdoesnothaveanEnglishversion.ThiscontentdoesnothaveanArabicversion.SectionsforHodgkin'slymphoma(Hodgkin'sdisease)Symptoms&causesDiagnosis&treatmentDoctors&departmentsCareatMayoClinicPrintOverviewLymphaticsystemOpenpop-updialogboxCloseLymphaticsystemLymphaticsystemYourbody'slymphaticsystemispartofyourimmunesystem,whichprotectsyouagainstinfectionanddisease.Thelymphaticsystemincludesyourspleen,thymus,lymphnodesandlymphchannels,aswellasyourtonsilsandadenoids.LymphnodeclustersOpenpop-updialogboxCloseLymphnodeclustersLymphnodeclustersLymphnodesarebean-sizedcollectionsoflymphocytes.About600ofthesenodesclusterthroughoutthelymphaticsystem,forexample,neartheknee,groin,neckandarmpits.Thenodesareconnectedbyanetworkoflymphaticvessels.Hodgkin'slymphoma—formerlyknownasHodgkin'sdisease—isacancerofthelymphaticsystem,whichispartofyourimmunesystem.Itmayaffectpeopleofanyage,butismostcommoninpeoplebetween20and40yearsoldandthoseover55.InHodgkin'slymphoma,cellsinthelymphaticsystemgrowabnormallyandmayspreadbeyondit.Hodgkin'slymphomaisoneoftwocommontypesofcancersofthelymphaticsystem.Theothertype,non-Hodgkin'slymphoma,isfarmorecommon.AdvancesindiagnosisandtreatmentofHodgkin'slymphomahavehelpedgivepeoplewiththisdiseasethechanceforafullrecovery.TheprognosiscontinuestoimproveforpeoplewithHodgkin'slymphoma.Hodgkin'slymphomacareatMayoClinicProducts&ServicesBook:MayoClinicFamilyHealthBook,5thEditionMayoClinic