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1. Epstein-Barr and Infectious Mononucleosis (Mono)

Epstein-Barr virus, or EBV, is one of the most common human viruses in the world. It spreads primarily through saliva. EBV can cause infectious mononucleosis, ...SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkEpstein-BarrVirusandInfectiousMononucleosisSectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateEpstein-BarrVirusandInfectiousMononucleosisMinusRelatedPagesEpstein-Barrvirus,orEBV,isoneofthemostcommonhumanvirusesintheworld.Itspreadsprimarilythroughsaliva.EBVcancauseinfectiousmononucleosis,alsocalledmono,andotherillnesses.MostpeoplewillgetinfectedwithEBVintheirlifetimeandwillnothaveanysymptoms.MonocausedbyEBVismostcommonamongteensandadults.MorelabiconAboutEpstein-BarrVirus(EBV)Describesthevirus,symptomsofEBVinfection,howEBVisspread,diagnosislabiconAboutInfectiousMononucleosisDescribestheillness,itssymptoms,howitspreads,treatmentandpreventionmedicaliconForHealthcareProvidersDescribesinfectiousmononucleosisandotherillnessesandcomplicationscausedbyEBVinfectionlabiconLaboratoryTestingExplainshowtouselaboratoryteststodiagnoseEBVinfectionbookiconReferences&ResourcesListsselectedscientificarticlesandbooksonEBVInfectiousMononucleosis(“Mono”)Typicalsymptomsofinfectiousmononucleosisinclude—extremefatiguefeversorethroatheadandbodyachesswollenlymphnodesintheneckandarmpitsswollenliverorspleenorbothrashMoreEBVSpreadsEasilyEBVisspreadbysalivathrough—kissingsharingdrinksandfoodusingthesamecups,eatingutensils,ortoothbrusheshavingcontactwithtoysthatchildrenhavedrooledonMoreElvirusdeEpstein-Barrylamononucleosisinfecciosa:LoquedebesaberSobreelvirusdeEpstein-Barr(VEB)QuéeslamononucleosisinfecciosaPagelastreviewed:September28,2020Contentsource:NationalCenterforImmunizationandRespiratoryDiseaseshomeEBVandMonoHomeAboutEpstein-BarrVirusAboutInfectiousMononucleosisForHealthcareProvidersLaboratoryTestingReferences&ResourcesFacebookTwitterLinkedInSASstatsExitNotification/DisclaimerPolicyCloseLinkswiththisiconindicatethatyouareleavingtheCDCwebsite.TheCentersforDis



2. 15 Epstein-Barr Virus Symptoms, Causes, Treatment ...

What Is an Epstein-Barr Virus Infection (EBV Infection)? · fever, · fatigue, · swollen tonsils, · headache, and · sweats, · sore throat, · swollen lymph nodes in the neck,​ ...homeinfectionscenterTopicGuideWhatAretheSymptomsofEpstein-BarrVirus?MedicalAuthor:JohnP.Cunha,DO,FACOEPMedicalEditor:JerryR.Balentine,DO,FACEPReviewedon10/7/2020DefinitionWhatIsanEpstein-BarrVirusInfection(EBVInfection)?Symptoms/SignsWhatAretheSymptomsandSignsEpstein-BarrVirus??IsItContagious?WhatCausesEpstein-BarrViralInfections?IsItContagious?CallaDoctorWhenShouldYouSeeaDoctorforEpstein-BarrVirus?Tests/DiagnosisWhatTestsDiagnoseEpstein-BarrViralInfections?TreatmentsWhatAretheTreatmentsforEpstein-BarrVirus?WhatNaturalandOver-the-CounterProductsHelpEpstein-BarrVirusSymptoms?PrognosisHowLongDoesItTakeforEpstein-BarrVirustoGoAway?WhatIsthePrognosisforMononucleosis?HowtoPreventHowCanYouPreventEpstein-BarrViralInfections?SpecialistsWhichTypesofDoctorsTreatEpstein-BarrVirus?MoreInfoWhereCanPeopleFindMoreInformationonEpstein-BarrVirusInfections?GuideEpstein-BarrVirus(EPV)TopicGuideDoctor'sNotesonEpstein-BarrVirusInfectionSymptomsWhatIsanEpstein-BarrVirusInfection(EBVInfection)?EBVisthecauseof infectiousmononucleosis (alsotermed"mono"),anillnessassociatedwith symptomsandsigns likefever,fatigue,swollentonsils,headache,andothersTheviruswasfirstdiscoveredin1964whenSirMichaelAnthonyEpsteinandMs.YvonneBarrfounditinaBurkittlymphomacellline.In1968,theviruswaslinkedtothediseaseofinfectiousmononucleosis(glandularfever).InfectionwithEpstein-Barrvirus(EBV)iscommonandusuallyoccursinchildhoodorearlyadulthood.EBVisthecauseofinfectiousmononucleosis(alsotermed"mono"),anillnessassociatedwithsymptomsandsignslike:fever,fatigue,swollentonsils,headache,andsweats,sorethroat,swollenlymphnodesintheneck,andsometimesanenlargedspleen(BPH,benignprostatichyperdysplasia),Itisalsoknownashumanherpesvirus4.AlthoughEBVcancausemononucleosis,noteveryoneinfectedwiththeviruswillgetmononucleosis.WhitebloodcellscalledBcellsaretheprimarytar



3. Glandular fever

Read about glandular fever, which is a type of viral infection that mostly affects young adults. Find out what the symptoms are, what you can do to treat it yourself​ ...SkiptomaincontentHomeHealthAtoZBacktoHealthAtoZGlandularfeverGlandularfevermostlyaffectsteenagersandyoungadults.Itgetsbetterwithouttreatment,butitcanmakeyoufeelveryillandlastforweeks.Non-urgentadvice:SeeaGPifyouhave:averyhightemperatureoryoufeelhotandshiveryaseveresorethroatswellingeithersideofyourneck–swollenglandsextremetirednessorexhaustiontonsillitisthatisnotgettingbetterTheseareglandularfeversymptoms.Youdonotusuallygetglandularfevermorethanonce.Information:Coronavirus(COVID-19)update:howtocontactaGPIt'sstillimportanttogethelpfromaGPifyouneedit.TocontactyourGPsurgery:visittheirwebsiteusetheNHSAppcallthemFindoutaboutusingtheNHSduringCOVID-19WhathappensatyourappointmentTheGPmightorderabloodtesttoconfirmit'sglandularfeverandtoruleoutotherillnesses,liketonsillitis.ThiswilltestfortheEpstein-Barrvirus,whichcausesglandularfever.TheGPwillnotgiveyouantibiotics.Glandularfeveriscausedbyavirussoantibioticswillnotwork.Immediateactionrequired:GotoA&Eorcall999ifyouhave:difficultyswallowingdifficultybreathingseverestomachpainHowtotreatglandularfeveryourselfThere'snocureforglandularfever–itgetsbetterbyitself.Dorestandsleepdrinkplentyoffluids(toavoiddehydration)takepainkillerslikeparacetamoloribuprofen(donotgiveaspirintochildrenunder16)Don’tdonotdrinkalcohol–yourlivermightbeweakwhileyouhaveglandularfeverVideo:Self-careforglandularfeverThisvideoexplainshowtotreatglandularfeveryourself.Medialastreviewed:1June2020Mediareviewdue:1June2023HowlongglandularfeverlastsYoushouldfeelbetterwithin2to3weeks.Somepeoplemightfeelextremelytiredformonths.Trytograduallyincreaseyouractivitywhenyourenergystartstocomeback.Glandularfevercancauseyourspleentoswell.Forthefirstmonth,avoidheavyliftingandsportsoractivitiesthatmightincreaseyourriskoffalling,asthismaydamageyourspleen.HowtostopglandularfeverspreadingGlandularfeverisspreadthrough



4. Epstein-Barr Virus (EBV): Symptoms, Prevention, Diagnosis ...

In this Article ... Epstein-Barr is the virus that causes mononucleosis. You might know this disease better by its nickname, "mono." It's also called the ...MenuMedicalReferenceSlideshows&ImagesQuizzesNewsArchiveNewsReferenceSlideshowsQuizzesVideosQuestions&AnswersWebMDRxSavingsCardCoronavirus(COVID-19)CBDOilKetoDietHepatitisCDiabetesWarningSignsRheumatoidArthritisMorning-AfterPillBreastCancerScreeningPsoriaticArthritisSymptomsHeartFailureMultipleMyelomaTypesofCrohn'sDiseaseAtoZGuidesReferenceMenuMedicallyReviewedbyCarolDerSarkissian, MDonJuly08,2019InthisArticleSymptomsHowItSpreadsDiagnosisTreatmentWhatYouCanDoatHomePreventionWhentoSeeYourDoctorOtherDiseasesCausedbyEBVEpstein-Barristhevirusthatcausesmononucleosis.Youmightknowthisdiseasebetterbyitsnickname,"mono."It'salsocalledthe"kissingdisease"becauseofonewayyoucanspreadittosomeoneelse.EventhoughEpstein-Barrvirus(EBV)isn'tahouseholdname,you'veprobablybeeninfectedwithoutknowingit.Lotsofpeoplecarrythevirusbutdon'tgetsick.SymptomsOnceyou'reinfectedwithEBV,symptomscantake4to6weekstoshowup.Whentheydo,they'reoftenmild,especiallyinyoungchildren.Kids'symptomsmaybemorelikethoseofacoldorflu.Teensoftenhavemoreobvioussymptomsofmono.Ifyoudogetsymptoms,mostlikelyyou'llhave:FatigueFeverLackofappetiteRashSorethroatSwollenglandsintheneckWeaknessandsoremusclesAlthoughyoushouldstartfeelingbetterin2to4weeks,thefatiguecanstickaroundmuchlonger.Youmaystillfeeltiredacoupleofmonthslater.HowItSpreadsThevirusisfoundinsaliva,soyoucancatchmonofromkissingsomeonewho’sinfected.Youcanalsogetitfromdrinkingfromthesameglassorusinganinfectedperson'stoothbrush.It'salsofoundinbloodandsemen,soit'spossibletogetmonofromsex,abloodtransfusion,oranorgantransplant.Youdon'thavetobesicktopassthevirustosomeoneelse.EBVstaysinyourbodylongafteryougetovermono.Theviruscanbecomeactiveagainmonthsoryearslater,makingyoucontagiousoncemore.DiagnosisIt'shardtotellwhetheryouhavemononucleosisjustbyyoursymptoms.Fever,fatigue,andsorethroatcouldalsobesignsofotherillnesses,liketh



5. About Epstein-Barr Virus (EBV)

SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkEpstein-BarrVirusandInfectiousMononucleosisSectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateAboutEpstein-BarrVirus(EBV)Español(Spanish)MinusRelatedPagesOnThisPageSymptomsTransmissionDiagnosisPrevention&TreatmentEpstein-Barrvirus(EBV),alsoknownashumanherpesvirus4,isamemberoftheherpesvirusfamily.Itisoneofthemostcommonhumanviruses.EBVisfoundallovertheworld.MostpeoplegetinfectedwithEBVatsomepointintheirlives.EBVspreadsmostcommonlythroughbodilyfluids,primarilysaliva.EBVcancauseinfectiousmononucleosis,alsocalledmono,andotherillnesses.SymptomsSymptomsofEBVinfectioncanincludefatiguefeverinflamedthroatswollenlymphnodesintheneckenlargedspleenswollenliverrashManypeoplebecomeinfectedwithEBVinchildhood.EBVinfectionsinchildrenusuallydonotcausesymptoms,orthesymptomsarenotdistinguishablefromothermild,briefchildhoodillnesses.PeoplewhogetsymptomsfromEBVinfection,usuallyteenagersoradults,getbetterintwotofourweeks.However,somepeoplemayfeelfatiguedforseveralweeksorevenmonths.AfteryougetanEBVinfection,thevirusbecomeslatent(inactive)inyourbody.Insomecases,thevirusmayreactivate.Thisdoesnotalwayscausesymptoms,butpeoplewithweakenedimmunesystemsaremorelikelytodevelopsymptomsifEBVreactivates.EBVSpreadsEasilyEBVisspreadbysalivathrough:kissingsharingdrinksandfoodusingthesamecups,eatingutensils,ortoothbrusheshavingcontactwithtoysthatchildrenhavedrooledonTransmissionEBVspreadsmostcommonlythroughbodilyfluids,especiallysaliva.However,EBVcanalsospreadthroughbloodandsemenduringsexualcontact,bloodtransfusions,andorgantransplantations.EBVcanbespreadbyusingobjects,suchasatoothbrushordrinkingglass,thataninfectedpersonrecentlyused.Thevirusprobablysurvivesonanobjectatleastaslongastheobjectremainsmoist.ThefirsttimeyougetinfectedwithEBV(primaryEBVinfection)youcanspreadthevirusforweeksandevenbeforeyouhavesymptoms.Oncethevirusisinyourbody,itstaysthereinalatent(inactive)state.Ifthevirusreactivates,youcanpotentiallyspreadEBVtoothersnoma



6. Epstein-Barr Virus: What to Know, From Mono to Cancer

What is it? ... Epstein-Barr virus (EBV) is a member of the herpesvirus family that can infect humans. EBV infections are very common — you've ...EverythingYouNeedtoKnowAboutEpstein-BarrVirusMedicallyreviewedbyKarenGill,M.D.—WrittenbyJillSeladi-Schulman,Ph.D.onMarch27,2019SymptomsReactivationsymptomsTransmissionTestTreatmentComplicationsCancerOtherconditionsWhatisit?Epstein-Barrvirus(EBV)isamemberoftheherpesvirusfamilythatcaninfecthumans.EBVinfectionsareverycommon—you’veprobablyalreadycontractedtheviruswithoutevenknowingit.TheconditionthatyoumayassociateEBVinfectionwithisinfectiousmononucleosis,ormono.However,expertsareresearchingpotentiallinksbetweenEBVandotherconditions,includingcancerandautoimmunediseases.ReadontolearnmoreaboutEBV,includingcommonsymptomsofaninfectionandhowthevirusspreads.Whatarethesymptoms?EBVinfectionsdon’talwayscausesymptoms.Thisisespeciallytrueforchildren.Teensandadultsaremorelikelytoexperiencesymptoms,whichcaninclude:feverfeelingtiredorfatiguedheadachesorethroatswollenlymphnodesinyourneckorunderyourarmsswollentonsilsenlargedspleen(splenomegaly)skinrashThesesymptomscanlastfortwotofourweeks,thoughfeelingsoffatiguemaylingerforweeksormonths.Whataboutsymptomsofreactivation?Onceyou’vebeeninfectedwithEBV,thevirusremainsinactivewithinyourbodyfortherestofyourlife.Thisiscalledlatency.Insomecases,theviruscanreactivate.Butthisusuallydoesn’tcauseanysymptoms.However,reactivatedEBVmaycausesymptomssimilartothoseofaninitialEBVinfectioninpeoplewhohaveaweakenedimmunesystem.Howdoesthevirusspread?EBVspreadsfrompersontopersonthroughbodilyfluids,particularlysaliva.Thisiswhymononucleosis,oneofthemostwell-knownEBVinfections,iscasuallyknownasthe“kissingdisease.”Butyoucanalsogetthevirusbysharingpersonalitems,suchastoothbrushesoreatingutensils,withsomeonewhohasanactiveEBVinfection.EBVcanalsobespreadthroughbloodandsemen.YoucanstartspreadingEBVtoothersassoonasyoucontractit.Thismeansyoucanpassitontoothersbeforeyouevenstarttohavesymptomsofanactiveinfection.You’llbeabletopas



7. Epstein–Barr virus

The Epstein–Barr virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of ...Epstein–BarrvirusFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchVirusoftheherpesfamilyHumangammaherpesvirus4ElectronmicrographoftwoEpstein–Barrvirions(viralparticles)showingroundcapsidslooselysurroundedbythemembraneenvelopeVirusclassification(unranked):VirusRealm:DuplodnaviriaKingdom:HeunggongviraePhylum:PeploviricotaClass:HerviviricetesOrder:HerpesviralesFamily:HerpesviridaeGenus:LymphocryptovirusSpecies:Humangammaherpesvirus4Synonyms[1]Epstein-BarrvirusHumanherpesvirus4HHV-4EBVTheEpstein–Barrvirus(EBV),formallycalledHumangammaherpesvirus4,isoneofthenineknownhumanherpesvirustypesintheherpesfamily,andisoneofthemostcommonvirusesinhumans.EBVisadouble-strandedDNAvirus.[2]Itisbestknownasthecauseofinfectiousmononucleosis("mono"or"glandularfever").Itisalsoassociatedwithvariousnon-malignant,premalignant,andmalignantEpstein–Barrvirus-associatedlymphoproliferativediseasessuchasBurkittlymphoma,hemophagocyticlymphohistiocytosis,[3]andHodgkin'slymphoma;non-lymphoidmalignanciessuchasgastriccancerandnasopharyngealcarcinoma;andconditionsassociatedwithhumanimmunodeficiencyvirussuchashairyleukoplakiaandcentralnervoussystemlymphomas.[4][5]ThevirusisalsoassociatedwiththechildhooddisordersofAliceinWonderlandsyndrome[6]andacutecerebellarataxia[7]and,basedonsomeevidence,higherrisksofdevelopingcertainautoimmunediseases,[8]especiallydermatomyositis,systemiclupuserythematosus,rheumatoidarthritis,Sjögren'ssyndrome,[9][10]andmultiplesclerosis.[11][12][13]About200,000cancercasesperyeararethoughttobeattributabletoEBV.[14][15]InfectionwithEBVoccursbytheoraltransferofsaliva[16]andgenitalsecretions.MostpeoplebecomeinfectedwithEBVandgainadaptiveimmunity.IntheUnitedStates,abouthalfofallfive-year-oldchildrenandabout90%ofadultshaveevidenceofpreviousinfection.[17]InfantsbecomesusceptibletoEBVassoonasmaternalantibodyprotectiondisapp



8. Mononucleosis (Mono): Symptoms, Treatment & Diagnosis

NowschedulingCOVID-19vaccineappointmentsforages12+ScheduleavaccineappointmentCOVID-19vaccineFAQsGoingtoaClevelandCliniclocation?NewvisitationhoursMasksarerequiredforpatientsandvisitors(evenifyou'revaccinated)Home/HealthLibrary/Disease&ConditionsMononucleosisMononucleosis(mono)isacontagiousinfectioncausedbyaherpesviruscalledEpstein-Barr.Othervirusescanalsocausemono.Theinfectioniscommonamongteenagersandyoungadults.Peoplewithmonoexperienceextremefatigue,feverandbodyaches.Treatmentscaneasesymptomsuntiltheillnessgoesawayonitsown.Appointments&AccessContactUsOverviewSymptomsandCausesDiagnosisandTestsManagementandTreatmentPreventionOutlook/PrognosisLivingWithMononucleosisOverviewSymptomsandCausesDiagnosisandTestsManagementandTreatmentPreventionOutlook/PrognosisLivingWithBackToTopOverviewWhatismononucleosis(mono)?Mononucleosisisanillnessthatcommonlyaffectsteenagersandyoungadults,butcanaffectchildrenaswell.Viruses,mostcommonlyEpstein-BarrVirus(EBV),andcertaininfectionscausetheillness.Monoissometimescalled“thekissingdisease”becauseitspreadseasilythroughbodilyfluidslikesaliva.Formostpeople,monoisn’tserious,anditimproveswithouttreatment.Still,extremefatigue,bodyachesandothersymptomscaninterferewithschool,workanddailylife.Withmono,youmightfeelsickforaboutamonth.Howcommonismononucleosis(mono)?TheEpstein-Barrvirus(EBV)thatcausesmonoisextremelycommon.Around90%ofAmericansareinfectedwithitbyage35.Noteveryonewhohasthevirusdevelopsmonosymptoms—somepeopleonlycarrythevirus.Whomightgetmononucleosis(mono)?ThereareoftentwopeakswhenpeopleacquireEBV:earlyschoolagechildrenandagainaroundadolescence/youngadulthood.Youngchildrenareoftenasymptomatic,whereasteenagersandpeopleintheir20saremostlikelytogetmono.AboutoneinfourpeopleinthisagegroupwhogetEBVcomedownwithmono,butanyonecangetit,nomattertheirage.Ismonoasexuallytransmittedinfection?Epstein-Barrisatypeofherpesvirus.It’sdifferentthantheherpessimplexvirus(HSV)thatcausesgenitalandoralherpes.Bothvirusescanbesexuallytransmitted.However,EBVismorelikely



9. About Epstein-Barr Virus (EBV)

Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpes virus family. It is one of the most common human viruses. EBV is found ...SkipdirectlytositecontentSkipdirectlytopageoptionsSkipdirectlytoA-ZlinkEpstein-BarrVirusandInfectiousMononucleosisSectionNavigationCDCHomeFacebookTwitterLinkedInSyndicateAboutEpstein-BarrVirus(EBV)Español(Spanish)MinusRelatedPagesOnThisPageSymptomsTransmissionDiagnosisPrevention&TreatmentEpstein-Barrvirus(EBV),alsoknownashumanherpesvirus4,isamemberoftheherpesvirusfamily.Itisoneofthemostcommonhumanviruses.EBVisfoundallovertheworld.MostpeoplegetinfectedwithEBVatsomepointintheirlives.EBVspreadsmostcommonlythroughbodilyfluids,primarilysaliva.EBVcancauseinfectiousmononucleosis,alsocalledmono,andotherillnesses.SymptomsSymptomsofEBVinfectioncanincludefatiguefeverinflamedthroatswollenlymphnodesintheneckenlargedspleenswollenliverrashManypeoplebecomeinfectedwithEBVinchildhood.EBVinfectionsinchildrenusuallydonotcausesymptoms,orthesymptomsarenotdistinguishablefromothermild,briefchildhoodillnesses.PeoplewhogetsymptomsfromEBVinfection,usuallyteenagersoradults,getbetterintwotofourweeks.However,somepeoplemayfeelfatiguedforseveralweeksorevenmonths.AfteryougetanEBVinfection,thevirusbecomeslatent(inactive)inyourbody.Insomecases,thevirusmayreactivate.Thisdoesnotalwayscausesymptoms,butpeoplewithweakenedimmunesystemsaremorelikelytodevelopsymptomsifEBVreactivates.EBVSpreadsEasilyEBVisspreadbysalivathrough:kissingsharingdrinksandfoodusingthesamecups,eatingutensils,ortoothbrusheshavingcontactwithtoysthatchildrenhavedrooledonTransmissionEBVspreadsmostcommonlythroughbodilyfluids,especiallysaliva.However,EBVcanalsospreadthroughbloodandsemenduringsexualcontact,bloodtransfusions,andorgantransplantations.EBVcanbespreadbyusingobjects,suchasatoothbrushordrinkingglass,thataninfectedpersonrecentlyused.Thevirusprobablysurvivesonanobjectatleastaslongastheobjectremainsmoist.ThefirsttimeyougetinfectedwithEBV(primaryEBVinfection)youcanspreadthevir



10. Clinical manifestations and treatment of Epstein-Barr virus ...

EBV is the primary agent of infectious mononucleosis (IM), persists asymptomatically for life in nearly all adults, and is associated with the ...



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