What Is an Epstein-Barr Virus Infection (EBV Infection)? · fever, · fatigue, · swollen tonsils, · headache, and · sweats, · sore throat, · swollen lymph nodes in the neck,​ ...homeinfectionscenterTopicGuideWhatAretheSymptomsofEpstein-BarrVirus?MedicalAuthor:JohnP.Cunha,DO,FACOEPMedicalEditor:JerryR.Balentine,DO,FACEPReviewedon10/7/2020DefinitionWhatIsanEpstein-BarrVirusInfection(EBVInfection)?Symptoms/SignsWhatAretheSymptomsandSignsEpstein-BarrVirus??IsItContagious?WhatCausesEpstein-BarrViralInfections?IsItContagious?CallaDoctorWhenShouldYouSeeaDoctorforEpstein-BarrVirus?Tests/DiagnosisWhatTestsDiagnoseEpstein-BarrViralInfections?TreatmentsWhatAretheTreatmentsforEpstein-BarrVirus?WhatNaturalandOver-the-CounterProductsHelpEpstein-BarrVirusSymptoms?PrognosisHowLongDoesItTakeforEpstein-BarrVirustoGoAway?WhatIsthePrognosisforMononucleosis?HowtoPreventHowCanYouPreventEpstein-BarrViralInfections?SpecialistsWhichTypesofDoctorsTreatEpstein-BarrVirus?MoreInfoWhereCanPeopleFindMoreInformationonEpstein-BarrVirusInfections?GuideEpstein-BarrVirus(EPV)TopicGuideDoctor'sNotesonEpstein-BarrVirusInfectionSymptomsWhatIsanEpstein-BarrVirusInfection(EBVInfection)?EBVisthecauseof infectiousmononucleosis (alsotermed"mono"),anillnessassociatedwith symptomsandsigns likefever,fatigue,swollentonsils,headache,andothersTheviruswasfirstdiscoveredin1964whenSirMichaelAnthonyEpsteinandMs.YvonneBarrfounditinaBurkittlymphomacellline.In1968,theviruswaslinkedtothediseaseofinfectiousmononucleosis(glandularfever).InfectionwithEpstein-Barrvirus(EBV)iscommonandusuallyoccursinchildhoodorearlyadulthood.EBVisthecauseofinfectiousmononucleosis(alsotermed"mono"),anillnessassociatedwithsymptomsandsignslike:fever,fatigue,swollentonsils,headache,andsweats,sorethroat,swollenlymphnodesintheneck,andsometimesanenlargedspleen(BPH,benignprostatichyperdysplasia),Itisalsoknownashumanherpesvirus4.AlthoughEBVcancausemononucleosis,noteveryoneinfectedwiththeviruswillgetmononucleosis.WhitebloodcellscalledBcellsaretheprimarytar