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1. Wernicke encephalopathy
Wernicke encephalopathy, also referred as Wernicke-Korsakoff syndrome, is a form of thiamine (vitamin B1) deficiency, and is typically seen in alcoholics.×ArticlesLogInCasesSignUpCoursesQuizBlogDonateAbout×MenuSearchADVERTISEMENT:Radiopaediaisfreethankstooursupportersandadvertisers.BecomeaGoldSupporterandseenoads.ArticlesCasesCoursesLogInLoginSignup{"url":"/signup-modal-props.json?lang=us\u0026email="}ArticlesCasesCoursesQuizAboutBlogGoad-freeSearchWernickeencephalopathyDrHenryKnipe◉◈andAssocProfFrankGaillard◉◈etal.Wernickeencephalopathy, alsoreferredasWernicke-Korsakoffsyndrome,isaformofthiamine(vitaminB1)deficiency,andistypicallyseeninalcoholics.Onimaging,itiscommonlyseenonMRIasareasofsymmetricalincreasedT2/FLAIRsignalinvolvingthemammillarybodies,dorsomedialthalami,tectalplate,periaqueductalarea and/oraroundthethirdventricle.Onthispage:Article:ClinicalpresentationPathologyRadiographicfeaturesTreatmentandprognosisHistoryandetymologyDifferentialdiagnosisRelatedarticlesReferencesImages:CasesandfiguresClinicalpresentationItwasoriginallydescribedascharacterizedbythetriadof:acuteconfusionataxiaophthalmoplegia(mostcommonlyhorizontalnystagmusandconjugategazepalsies)WernickeencephalopathycanevolveintothechronicformofthiaminedeficiencyknownasKorsakoffpsychosis,characterizedby:memoryloss(globalamnesia)confabulationThetwotermsareoftenconcatenatedtoformWernicke-Korsakoffsyndrome.PathologyEtiologyThiaminedeficiencyresultsfrommalnutritionormalabsorption,whichcanoccurforanumberofreasons6,7:alcoholabuse(upto90%inindustrialisedcountries5)starvation/fastingprolongedtotalparenteralnutritionwithoutsupplementationpostbariatricsurgeryhyperemesisgravidarumgastrointestinalmalignancychronicdialysisRadiographicfeaturesInacutestages,hemorrhage,necrosis,andedemamaybepresent.Inchronicstages,atrophicchangesmaybepresentespeciallyinvolvingthemamillarybodies.CTUsuallynormal.MRIT2/FLAIR: symmetricallyincreasedsignalintensityinthemammillarybodiesdorsomedialthalamitectalplateperiaqueductalgreymattera
2. Wernicke Encephalopathy—Clinical Pearls
Wernicke encephalopathy is a medical emergency that is poorly understood and underrecognized. Although most prevalent in patients with alcohol ...
3. Neuro-ophthalmic Manifestations of Wernicke ...
Abstract: Wernicke encephalopathy (WE) is a life-threatening but reversible syndrome resulting from acute thiamine deficiency that is frequently ...JournalsWhyPublishWithUs?EditorialPoliciesAuthorGuidelinesPeerReviewGuidelinesOpenOutlookCOVID-19BlogReprintsSubmitNewManuscriptMenuAboutContactSustainabilityAwardsPressCenterTestimonialsBlogFavoredAuthorProgramPermissionsPre-SubmissionReprintsLoginopenaccesstoscientificandmedicalresearchAdvancedsearchHomeJournalsWhypublishwithus?EditorialPoliciesAuthorInformationPeerReviewGuidelinesOpenOutlookCOVID-19AverageArticleStatistics28Days*Fromsubmissiontofirsteditorialdecision.*Businessdays(Mon-Fri)RejectionRate56%Theabovepercentageofmanuscriptshavebeenrejectedinthelast12months.65386PapersPublishedSubmitNewManuscriptLogintoviewexistingmanuscriptstatusSignupforJournalalertsAboutDovePressOpenaccesspeer-reviewedscientificandmedicaljournals.LearnmoreOpenAccessDoveMedicalPressisamemberoftheOAI.LearnmoreReprintsBulkreprintsforthepharmaceuticalindustry.LearnmoreFavoredAuthorsWeofferrealbenefitstoourauthors,includingfast-trackprocessingofpapers.LearnmorePromotionalArticleMonitoringRegisteryourspecificdetailsandspecificdrugsofinterestandwewillmatchtheinformationyouprovidetoarticlesfromourextensivedatabaseandemailPDFcopiestoyoupromptly.LearnmoreSocialMedia BacktoJournals»EyeandBrain»Volume12ReviewNeuro-ophthalmicManifestationsofWernickeEncephalopathy FulltextMetricsGetPermissionCitethisarticleAuthorsIsenDR,KlineLBReceived1May2020Acceptedforpublication9June2020Published30June2020Volume2020:12Pages49—60DOIhttps://doi.org/10.2147/EB.S234078CheckedforplagiarismYesReviewbySingleanonymouspeerreviewPeerreviewercomments2Editorwhoapprovedpublication:ProfessorMargaretWong-RileyDownloadArticle[PDF] DanielleRIsen,1LanningBKline21DepartmentofNeurology,UniversityofSouthAlabamaSchoolofMedicine,Mobile,AL,USA;2DepartmentofOphthalmology,UniversityofAlabamaSchoolofMedicine,Birmingham,AL,USACorrespondence:LanningBKlineDepartmentofOphthal
4. Wernicke-Korsakoff Syndrome: Symptoms, Causes, Treatment
Wernicke encephalopathy typically comes on suddenly, and you'll need treatment right away. Symptoms include confusion, loss of muscle ...News&FeaturesReferenceSlideshowsQuizzesVideosQuestions&AnswersFindaNeurologistLivingBetterWithMSADHDAlzheimer'sDiseaseAutismConcussionCreutzfeldt-JakobDiseaseEpilepsyGuillain-BarréSyndromeLouGehrig’sDisease(ALS)MultipleSclerosisParkinson'sDiseaseRestlessLegsSyndromeSpinalMuscularAtrophyStrokeMoreRelatedTopicsBrain&NervousSystemReferenceReviewedbyHansaD.Bhargava, MDonJuly16,2020InthisArticleWhatIsWernicke-KorsakoffSyndrome?Wernicke-KorsakoffSyndromeSymptomsWernicke-KorsakoffSyndromeCausesandRiskFactorsWernicke-KorsakoffSyndromeDiagnosisWernicke-KorsakoffSyndromeTreatmentWernicke-KorsakoffSyndromeComplicationsWernicke-KorsakoffSyndromeOutlookWhatIsWernicke-KorsakoffSyndrome?Wernicke-Korsakoffsyndrome(WKS)isonenamefortwoconditionsthatoftenhappentogether--WernickeencephalopathyandKorsakoffsyndrome.Manydoctorsthinkofthemasdifferentstagesofthesamedisease.Theycanhappenifyoudon’tgetenoughvitaminB1,alsocalledthiamine.VitaminB1helpsyourbrainturnsugarintoenergy.Whenyourbrainandnervoussystemdon’tgettheamounttheyneed,theydon’tworkaswell.Wernickeencephalopathytypicallycomesonsuddenly,andyou’llneedtreatmentrightaway.Symptomsincludeconfusion,lossofmusclecoordination,andtroublewithyourvision.Korsakoffsyndromehappensmoreslowly.It’salong-term,ongoingproblemthatdamagesthepartofyourbrainthathandlesmemory.Wernicke-KorsakoffSyndromeSymptomsThemainsignsofWernickeencephalopathyare:Balanceandmovementissues.Youmighthavelegtremors,andyourwalkmightbecomeslowandunsteady,withawidestanceandshortsteps.Youmayneedhelpstandingandgettingaround,andyourarmsandlegsmightfeelweak.Confusion.Youmayfeeloutofitandloseinterestinwhat’shappeningaroundyou.Eyeproblems.Youmayhavedoublevision,youreyelidsmightdroop,oryoureyesmaymovearoundquickly.ContinuedYoualsomayhaveproblemswithyourheartandbloodvesselsthatcanleadto:DrowsinessFaintingAfasterheartbeatthannormalLowbloodpressurewhenyous
5. Wernicke encephalopathy
Wernicke encephalopathy (WE) is an acute syndrome requiring emergent treatment to prevent death and neurologic morbidity. Korsakoff ...