How Is Gestational Trophoblastic Disease Diagnosed? | Gestational trophoblastic disease

Whatpatientsandcaregiversneedtoknowabout cancer,coronavirus,andCOVID-19.CloseCriticalAlertBannerSearch|Downloadthistopic[PDF]EarlyDetection,Diagnosis,andStagingCanGestationalTrophoblasticDiseaseBeFoundEarly?SignsandSymptomsofGestationalTrophoblasticDiseaseHowIsGestationalTrophoblasticDiseaseDiagnosed?HowIsGestationalTrophoblasticDiseaseStaged?WhatShouldYouAskYourDoctorAboutGestationalTrophoblasticDisease?CancerA-ZGestationalTrophoblasticDiseaseEarlyDetection,Diagnosis,andStagingHowIsGestationalTrophoblasticDiseaseDiagnosed?Gestationaltrophoblasticdisease(GTD)ismostoftenfoundeitherasaresultofabnormalsignsorsymptomsduringpregnancyorfromtheresultsofcertaintestsduringroutineprenatalcare.Thesemayleadthedoctortoorderothertests.BloodandurinetestsBloodandurinetestscanbeusedtohelpdiagnoseGTD.Humanchorionicgonadotropin(HCG)TrophoblasticcellsofbothnormalplacentasandGTDmakeahormonecalledhumanchorionicgonadotropinorHCG,whichisvitalinsupportingapregnancy.HCGisreleasedintotheblood,andsomeofitisexcretedintheurine.Thishormonehas2chemicalcomponents,andthecommonlyusedbloodandurinetestsmeasureoneofthese,calledbeta-HCG(βHCG).HCGisnormallyfoundonlyinthebloodorurineofpregnantwomen.Infact,findingHCGinurineisthebasisofmostpregnancytests.AcompletemoleusuallyreleasesmoreHCGthananormalplacenta,sofindinghigherthanexpectedHCGlevelsinthebloodcanbeasignthatacompletemoleispresent.However,notallwomenwithGTDhaveHCGlevelsthatarehigherthanthoseseeninanormalpregnancy.Forexample,mostwomenwithpartialmoles,placentalsitetrophoblastictumors,andepithelioidtrophoblastictumorshavenormaloronlyslightlyincreasedHCGlevels.HCGtestscanalsohelptellifGTDmaybepresentafterapregnancyormiscarriage,asthelevelofHCGshouldnormallyfalltoanundetectablelevelsoonafterward.AlongwithhelpingtodiagnoseGTD,bloodHCGlevelsarealsoveryusefulinwomenalreadyknowntohaveGTD.Theycanbeusedto:HelpestimatetheamountofGTDpresentinapatient'sbody.HigherlevelsofHCGmight meanthattherearemoretumorcellsinthebody.Determineiftreatmentisworking.HCGlevelsshoul


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