Persistent infections with Chlamydia pneumoniae have been implicated in the development of chronic diseases, such as atherosclerosis and asthma.NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutTryoutPMCLabsandtelluswhatyouthink.LearnMore.JournalListAntimicrobAgentsChemotherv.46(2);2002FebPMC127037AntimicrobAgentsChemother.2002Feb;46(2):409–412.doi: 10.1128/AAC.46.2.409-412.2002PMCID:PMC127037PMID:11796350EffectofProlongedTreatmentwithAzithromycin,Clarithromycin,orLevofloxacinonChlamydiapneumoniaeinaContinuous-InfectionModelAndreiKutlin,PatriciaM.Roblin,andMargaretR.Hammerschlag*AndreiKutlinDepartmentofPediatrics,StateUniversityofNewYorkHealthScienceCenteratBrooklyn,Brooklyn,NewYorkFindarticlesbyAndreiKutlinPatriciaM.RoblinDepartmentofPediatrics,StateUniversityofNewYorkHealthScienceCenteratBrooklyn,Brooklyn,NewYorkFindarticlesbyPatriciaM.RoblinMargaretR.HammerschlagDepartmentofPediatrics,StateUniversityofNewYorkHealthScienceCenteratBrooklyn,Brooklyn,NewYorkFindarticlesbyMargaretR.HammerschlagAuthorinformationArticlenotesCopyrightandLicenseinformationDisclaimerDepartmentofPediatrics,StateUniversityofNewYorkHealthScienceCenteratBrooklyn,Brooklyn,NewYork*Correspondingauthor.Mailingaddress:DepartmentofPediatrics,Box49,SUNYDownstateMedicalCenteratBrooklyn,450ClarksonAve.,Brooklyn,NY11203-2098.Phone:(718)245-4075.Fax:(718)245-2118.E-mail:[email protected];Revised2001Aug14;Accepted2001Nov4.Copyright©2002,AmericanSocietyforMicrobiologyThisarticlehasbeencitedbyotherarticlesinPMC.PersistentinfectionswithChlamydiapneumoniaehavebeenimplicatedinthedevelopmentofchronicdiseases,suchasatherosclerosisandasthma.Althoughazithromycin,clarithromycin,andlevofloxacinarefrequentlyusedforthetreatmentofrespiratoryC.pneumoniaeinfections,littleisknownaboutthedoseanddurationoftherapyneededtotreataputativechronicC.pneumoniaeinfection.Inthisstudy,weinvestigatedtheeffectofprolongedtreatmentwithazithromycin,clarithromycin,orlevoflox