Rare soft tissue tumor, morphologically indistinguishable from Ewing sarcoma of bone, may represent extension of bone tumor into soft tissue ...AuthorsBlogBoardReviewCommentContactUsNewslettersStatisticsTestimonialsSeeElsevier'snewvideoabouttheirClinicReviewArticlesonourhomepageorclickhere.JobsFellowshipsConferences/WebinarsBooksCMECasesAdvertiseGrantsMedicalNewsLibrariesRocheCompanionDiagnosticLibraryRocheNTRKIHCDiagnosticLibraryCOVID-19LibraryPandemicreliefmusicawardHome>Softtissue>Ewingsarcoma/PNETSofttissueExtraskeletalbonetumorsEwingsarcoma/PNETAuthor: VijayShankar,M.D.TopicCompleted:1November2012Minorchanges:20November2020Copyright:2002-2021,PathologyOutlines.com,Inc.PubMedSearch:ExtraskeletalEwingsarcoma/PNETPageviewsin2020:8,076Pageviewsin2021todate:2,408TableofContentsDefinition/general|Radiologyimages|Casereports|Clinicalimages|Grossimages|Microscopic(histologic)description|Microscopic(histologic)images|Positivestains|Negativestains|Electronmicroscopydescription|Molecular/cytogeneticsdescription|DifferentialdiagnosisCitethispage:ShankarV.Ewingsarcoma/PNET.PathologyOutlines.comwebsite.https://www.pathologyoutlines.com/topic/softtissuePNET.html.AccessedApril13th,2021.Definition/generalRaresofttissuetumor,morphologicallyindistinguishablefromEwingsarcomaofbone,mayrepresentextensionofbonetumorintosofttissueUsuallyage30orless,occasionallyage50+,usuallymalepreponderanceOftenchestwall,lowerextremities,paravertebralregion;alsopelvis,hipregion,retroperitoneum,upperextremities(Cancer2011;117:3027)Aggressive;commonmetastasestolung,bonesRadiologyimagesContributedbyMarkR.Wick,M.D.ChestwallCasereports29yearoldmanwithnecktumorexhibitingfocalsquamousdifferentiation(AmJSurgPathol2008;32:1742)35yearoldwomanwithabdominalwallmass(CancerImaging2008;8:156)77yearoldwomanwithinguinalmass(ArchPatholLabMed2001;125:1358)ClinicalimagesContributedbyMarkR.Wick,M.D.HandGrossimagesContributedbyMarkR.Wick,M.D. Superficial(left)andsubcuticular(right)ContributedbySemirVranić,M.D.,Ph.D.Lowgra