Splenic marginal zone B-cell lymphoma: This disease is found in the spleen and bone marrow, and is most common in older men. In some cases, this ...We'reavailable24/7.Callusanytime.(888)552-6760B-celllymphomaT-celllymphomaWaldenstrommacroglobulinemiaTheinformationonthispagewasreviewedandapprovedbyMaurieMarkman,MD,President,Medicine&ScienceatCTCA.ThispagewasupdatedonSeptember21,2021.Non-HodgkinlymphomatypesNon-Hodgkinlymphomaisdividedintomorethan30types,classifiedbasedonthetypeoflymphocyteinvolved:Blymphocytes(Bcells)orTlymphocytes(Tcells).Non-Hodgkinlymphomaisfurtherclassifiedbyotherfactors,includingwhetheritisaggressive(fast-growing)orindolent(slow-growing).Aggressivelymphomasinclude:DiffuselargeB-celllymphomaAnaplasticlarge-celllymphomaBurkittlymphomaLymphoblasticlymphomaMantlecelllymphomaPeripheralT-celllymphomaIndolentlymphomasinclude:FollicularlymphomaCutaneousT-celllymphomaLymphoplasmacyticlymphomaMarginalzoneB-celllymphomaMALTlymphomaSmall-celllymphocyticlymphomaBurkittlymphomaBurkittlymphomaisconsideredthemostaggressiveformoflymphomaandisoneofthefastestgrowingofallcancers.Butitisveryrare,accountingforabout2percentofalllymphomadiagnoses.ThediseaseoriginatesinmatureB-lymphocytes,whicharecellsoftheacquiredimmunesystemthatproduceantibodiestohelpfightoffdisease.Burkittlymphoma,atypeofnon-Hodgkinlymphoma,ismostoftendiagnosed inyoungadultsandchildren,especiallymale.ButcertaintypesofBurkittlymphomahavebeendiagnosed inadults,especiallythosewithaweakenedimmunesystem.ThediseaseisnamedforDenisBurkitt,theBritishsurgeonwhofirstidentifiedthecancerinAfricanchildreninthelate1950s.ThesymptomsofBurkittlymphoma varygreatlyanddependonthedisease’stype.Symptomsmayspreadorworsenquicklyasthisaggressivecanceradvances.PatientswithendemicBurkittlymphomamayhaveswellingordisfigurementinthejaworface.PatientswithsporadicBurkittlymphomamayhaveswellingorpainintheabdomen.Thediseasemayalsospreadquicklytothecentralnervoussystemandbrain,causingsevereneurologicalsymptoms,includingparalysis.Others