a Series of 22 Patients and Treatment Strategy Review | 淋巴上皮癌
目的：原發性肺淋巴上皮瘤樣癌（LELC）是非小細胞肺癌的一種罕見亞型。
一系列有限的文獻提示原發性肺淋巴上皮瘤樣癌可能會比一般非小細胞肺癌的生存率高。
本文回顧 ...TreatmentOutcomesofPrimaryPulmonaryLymphoepithelioma-likeCarcinoma:aSeriesof22PatientsandTreatmentStrategyReviewFullArticleFSTMok,OSHChan,ATYChang,LLKChan,ISSoong,WTNg,FYCheung,RMWYeungHongKongJRadiol2013;16:270-7DOI:10.12809/hkjr1313176Objectives:Primarypulmonarylymphoepithelioma-likecarcinoma(LELC)isararesubgroupofnon–small-celllungcancer.Limitedpublishedseriessuggestedthatitmightbeassociatedwithmorefavourablesurvivalthanordinarynon–small-celllungcancer.WesetouttoreviewthetreatmentoutcomesofpatientswithprimarypulmonaryLELCtreatedinourinstitutionsince1994.Methods:AllpatientswithpathologicallyconfirmedprimarypulmonaryLELCtreatedbetween1994and2012wereretrospectivelyreviewed.Treatmentmodalitiesandoutcomes—includinglocalcontrolrate,disease-freeandoverallsurvival—wereanalysed.Results:Twenty-twopatientswithprimarypulmonaryLELCwereidentified.Theirmedianfollow-updurationwas33months(range,1dayto106months).SurgerywasthemainstayoftreatmentforpatientswithstageItoIIdiseases.Thosewithadvancednon-metastaticdisease(n=5)treatedwithhigh-doseradiotherapy(EQD260Gy)withorwithoutplatinum-basedchemotherapyhadalocalcontrolrateof100%afteramedianfollow-upof68months.The5-yearprogression-freesurvival(PFS)andoverallsurvival(OS)were53%and80%,respectively.TheirmedianPFSandOShadnotreachedatthetimeofpublication.ForpatientswithstagesIIIandIVdiseasebeyondradicalradiotherapyportals,palliativeplatinumdoubletsgaveamediandisease-freesurvivalof10monthsin12patients.The5-yearOSofstageI-II,III,andIVpatientswere41%,38%,and25%,respectively(p=0.61).TheirmedianOSdurationswere58,30,and19months,respectively.Conclusion:OurseriesechoedpriorsuggestionsthatprimarypulmonaryLELCachievesfavourableoutcomes. 中文摘要原發性肺淋巴上皮瘤樣癌的治療效果：22個病例以及其治療策略回顧莫小婷、陳少康、張天怡、陳麗君、宋崧、吳偉棠、張寬耀、楊美雲目的：原發性肺淋巴上皮瘤樣癌（LELC）是非小細胞肺癌的一種罕見亞型。
一系列有限的文獻提示原發性肺淋巴上皮瘤樣癌可能會比一般非小細胞肺癌的生存率高。
本文回顧自1994年以來，於我們醫院診治的原發性肺LELC患者的治療效果。
方法：回顧性分析所有1994至2012年期
一系列有限的文獻提示原發性肺淋巴上皮瘤樣癌可能會比一般非小細胞肺癌的生存率高。
本文回顧 ...TreatmentOutcomesofPrimaryPulmonaryLymphoepithelioma-likeCarcinoma:aSeriesof22PatientsandTreatmentStrategyReviewFullArticleFSTMok,OSHChan,ATYChang,LLKChan,ISSoong,WTNg,FYCheung,RMWYeungHongKongJRadiol2013;16:270-7DOI:10.12809/hkjr1313176Objectives:Primarypulmonarylymphoepithelioma-likecarcinoma(LELC)isararesubgroupofnon–small-celllungcancer.Limitedpublishedseriessuggestedthatitmightbeassociatedwithmorefavourablesurvivalthanordinarynon–small-celllungcancer.WesetouttoreviewthetreatmentoutcomesofpatientswithprimarypulmonaryLELCtreatedinourinstitutionsince1994.Methods:AllpatientswithpathologicallyconfirmedprimarypulmonaryLELCtreatedbetween1994and2012wereretrospectivelyreviewed.Treatmentmodalitiesandoutcomes—includinglocalcontrolrate,disease-freeandoverallsurvival—wereanalysed.Results:Twenty-twopatientswithprimarypulmonaryLELCwereidentified.Theirmedianfollow-updurationwas33months(range,1dayto106months).SurgerywasthemainstayoftreatmentforpatientswithstageItoIIdiseases.Thosewithadvancednon-metastaticdisease(n=5)treatedwithhigh-doseradiotherapy(EQD260Gy)withorwithoutplatinum-basedchemotherapyhadalocalcontrolrateof100%afteramedianfollow-upof68months.The5-yearprogression-freesurvival(PFS)andoverallsurvival(OS)were53%and80%,respectively.TheirmedianPFSandOShadnotreachedatthetimeofpublication.ForpatientswithstagesIIIandIVdiseasebeyondradicalradiotherapyportals,palliativeplatinumdoubletsgaveamediandisease-freesurvivalof10monthsin12patients.The5-yearOSofstageI-II,III,andIVpatientswere41%,38%,and25%,respectively(p=0.61).TheirmedianOSdurationswere58,30,and19months,respectively.Conclusion:OurseriesechoedpriorsuggestionsthatprimarypulmonaryLELCachievesfavourableoutcomes. 中文摘要原發性肺淋巴上皮瘤樣癌的治療效果：22個病例以及其治療策略回顧莫小婷、陳少康、張天怡、陳麗君、宋崧、吳偉棠、張寬耀、楊美雲目的：原發性肺淋巴上皮瘤樣癌（LELC）是非小細胞肺癌的一種罕見亞型。
一系列有限的文獻提示原發性肺淋巴上皮瘤樣癌可能會比一般非小細胞肺癌的生存率高。
本文回顧自1994年以來，於我們醫院診治的原發性肺LELC患者的治療效果。
方法：回顧性分析所有1994至2012年期