ThisarticleispartoftheResearchTopicAntiviralsforEmergingViruses:VaccinesandTherapeuticsViewall26ArticlesArticlesLijunRongUniversityofIllinoisatChicago,UnitedStatesYechielShaiWeizmannInstituteofScience,IsraelJinsongLiuGuangzhouInstitutesofBiomedicineandHealth,ChineseAcademyofSciences(CAS),ChinaTheeditorandreviewers'affiliationsarethelatestprovidedontheirLoopresearchprofilesandmaynotreflecttheirsituationatthetimeofreview.AbstractIntroductionMaterialsandMethodsResultsDiscussionDataAvailabilityAuthorContributionsFundingConflictofInterestStatementAcknowledgmentsReferencesSuggestaResearchTopic>DownloadArticleDownloadPDFReadCubeEPUBXML(NLM)SupplementaryMaterialExportcitationEndNoteReferenceManagerSimpleTEXTfileBibTextotalviewsViewArticleImpactSuggestaResearchTopic>SHAREONOriginalResearchARTICLEFront.Microbiol.,13August2019|https://doi.org/10.3389/fmicb.2019.01829CrystalStructureofRefoldingFusionCoreofLassaVirusGP2andDesignofLassaVirusFusionInhibitorsXuejiaoZhang1,2†,CongWang3†,BaohuaChen1†,QianWang3,WeiXu3,ShengYe1,4,ShiboJiang3,5*,YunZhu1*andRongguangZhang1,6*1NationalLaboratoryofBiomacromolecules,InstituteofBiophysics,ChineseAcademyofSciences,Beijing,China2CollegeofLifeSciences,UniversityofChineseAcademyofSciences,Beijing,China3KeyLaboratoryofMedicalMolecularVirologyofMOE/MOH/CAMS,SchoolofBasicMedicalSciencesandShanghaiPublicHealthClinicalCenter,Fudan-JinboJointResearchCenter,FudanUniversity,Shanghai,China4InterdisciplinaryInnovationInstituteofMedicineandEngineering,BeijingAdvancedInnovationCenterforBigData-BasedPrecisionMedicine,SchoolofBiologicalScienceandMedicalEngineering,BeihangUniversity,Beijing,China5LindsleyF.KimballResearchInstitute,NewYorkBloodCenter,NewYork,NY,UnitedStates6NationalCenterforProteinScienceShanghai,ShanghaiInstituteofBiochemistryandCellBiology,ShanghaiInstitutesforBiologicalSciences,ChineseAcademyofSciences,Shanghai,ChinaTheenvelopeglycoproteinsGP1andGP2ofLassavirus(LASV)bindtothehostcellreceptorstomediateviralinfection.Sofar,noapprovedvaccinesan