Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever caused by a tick-borne banyangvirus and is ...GotoJCIInsightAboutEditorsConsultingEditorsForauthorsAlertsAdvertising/recruitmentSubscribeContactCurrentIssuePastIssuesByspecialtyCOVID-19CardiologyGastroenterologyImmunologyMetabolismNephrologyNeuroscienceOncologyPulmonologyVascularbiologyAll...VideosConversationswithGiantsinMedicineAuthor'sTakesReviewsReviewsViewallreviews...ReviewSeriesTumorMicroenvironment(Mar2021)100thAnniversaryofInsulin'sDiscovery(Jan2021)Hypoxia-induciblefactorsindiseasepathophysiologyandtherapeutics(Oct2020)LatencyinInfectiousDisease(Jul2020)ImmunotherapyinHematologicalCancers(Apr2020)BigData'sFutureinMedicine(Feb2020)MechanismsUnderlyingtheMetabolicSyndrome(Oct2019)Viewallreviewseries...ViewpointCollectionsIn-PressPreviewCommentariesConciseCommunicationEditorialsViewpointTopreadarticlesClinicalMedicineJCIThisMonthCurrentissuePastissuesTheJournalofClinicalInvestigationCurrentissuePastissuesSpecialtiesReviewsReviewseriesVideosConversationswithGiantsinMedicineAuthor'sTakesCollectionsIn-PressPreviewCommentariesConciseCommunicationEditorialsViewpointTopreadarticlesJournalDetailsAboutEditorsConsultingEditorsForauthorsAlertsAdvertising/recruitmentSubscribeContactTopToolsViewPDFDownloadcitationinformationSendaletterSharethisarticleTermsofuseStandardabbreviationsNeedhelp?EmailthejournalGotoTopAbstractIntroductionResultsDiscussionMethodsAuthorcontributionsSupplementalmaterialAcknowledgmentsFootnotesReferencesVersionhistoryPDFMetricsArticleusageCitationstothisarticleAdvertisementResearchArticleInfectiousdiseaseVirologyFreeaccess|10.1172/JCI129171SeverefeverwiththrombocytopeniasyndromevirustargetsBcellsinlethalhumaninfectionsTadakiSuzuki,1YukoSato,1KaoriSano,1,2TakeshiArashiro,1HarutakaKatano,1NorikoNakajima,1MasayukiShimojima,3MichiyoKataoka,1KentaTakahashi,1YujiWada,1ShigeruMorikawa,4ShuetsuFukushi,3TomokiYoshikawa,3MasayukiSaijo,3andHidekiHasegawa1,2,51DepartmentofPatho