Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that recently emerged in East Asian countries.GotoTheJournalofClinicalInvestigationAboutEditorsConsultingEditorsForauthorsPublicationethicsTransfersAdvertising/recruitmentContactCurrentIssuePastIssuesByspecialtyCOVID-19CardiologyImmunologyMetabolismNephrologyOncologyPulmonologyAll...VideosCollectionsTechnicalAdvancesClinicalMedicineReviewsEditorialsPerspectivesTopreadarticlesJCIThisMonthCurrentissuePastissuesJCIInsightCurrentissuePastissuesSpecialtiesCollectionsIn-PressPreviewConciseCommunicationEditorialsViewpointTopreadarticlesJournalDetailsAboutEditorsConsultingEditorsForauthorsPublicationethicsTransfersAdvertising/recruitmentContactTopToolsViewPDFDownloadcitationinformationSendaletterSharethisarticleTermsofuseStandardabbreviationsNeedhelp?EmailthejournalGotoTopAbstractIntroductionResultsDiscussionMethodsAuthorcontributionsSupplementalmaterialAcknowledgmentsFootnotesReferencesVersionhistoryPDFMetricsArticleusageCitationstothisarticleAdvertisementResearchArticleInfectiousdiseaseTherapeuticsFreeaccess|10.1172/jci.insight.136855Asingle-domainantibodyinhibitsSFTSVandmitigatesvirus-inducedpathogenesisinvivoXilinWu,1YanleiLi,2BilianHuang,1XiaohuaMa,3LinjingZhu,4NanZheng,1ShijieXu,1WaqasNawaz,1ChangpingXu,1andZhiweiWu3,5,61CenterforPublicHealthResearch,MedicalSchool,NanjingUniversity,Nanjing,China.2Y-CloneMedicalScienceCo.Ltd.,Suzhou,China.3SchoolofLifeSciences,NingxiaUniversity,Yinchuan,China.4AbrevBiotechnologyCo.,Ltd.,Nanjing,China.5JiangsuKeyLaboratoryofMolecularMedicine,MedicalSchool,NanjingUniversity,Nanjing,China.6StateKeyLaboratoryofAnalyticalChemistryforLifeScience,NanjingUniversity,Nanjing,China.Addresscorrespondenceto:ZhiweiWu,SchoolofLifeSciences,NingxiaUniversity,539HelanshanRoadWest,Yinchuan750021,China.Phone:86.25.8368.6092;Email:[email protected]:XWandYLcontributedequallytothiswork.FindarticlesbyWu,X.in:JCI|PubMed|GoogleScholar1CenterforPublicHealthRes